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Bad trip
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<h2 id="signs-and-symptoms">Signs and symptoms</h2> <p class="note">See also: <a href="/facts/Psychosis/cVGd7MKK">Psychosis</a> and <a href="/facts/Substance-induced_psychosis/qyQH1Ay3">Substance-induced psychosis</a></p> <p>With proper screening, preparation, and support in a regulated setting these are usually benign.<a class="footnote-ref" id="fnref:8" href="#fn:8"><sup>8</sup></a> A bad trip on <a href="/facts/Psilocybin/0jGynLUX">psilocybin</a>, for instance, often features intense anxiety, confusion, agitation, and <a href="/facts/Psychosis/cVGd7MKK">psychosis</a>.<a class="footnote-ref" id="fnref:9" href="#fn:9"><sup>9</sup></a> They manifest as a range of feelings, such as anxiety, paranoia, the unshakeable sense of one's inevitable and imminent personal demise or states of unrelieved terror that they believe will persist after the substance's <a href="/facts/Pharmacokinetics/x4CUUnle">effects</a> have worn off. As of 2011, exact data on the frequency of bad trips are not available.<a class="footnote-ref" id="fnref:10" href="#fn:10"><sup>10</sup></a> </p> <h2 id="treatment">Treatment</h2> <p>Medical treatment consists of supportive therapy and minimization of external stimuli. In some cases, <a href="/facts/Sedation/wFWEChs8">sedation</a> is used when necessary to control self-destructive behavior, or when <a href="/facts/Hyperthermia/WMHlf9j7">hyperthermia</a> occurs. <a href="/facts/Diazepam/h7lIGqkM">Diazepam</a> is the most frequently used sedative for such treatment, but other <a href="/facts/Benzodiazepines/IgbJr4jy">benzodiazepines</a> such as <a href="/facts/Lorazepam/59gNSrMN">lorazepam</a> are also effective. Such sedatives will only decrease fear and anxiety, but will not subdue hallucinations. In severe cases, antipsychotics such as <a href="/facts/Haloperidol/ue4TJKmu">haloperidol</a> can reduce or stop hallucinations. Haloperidol is effective against acute intoxication caused by LSD and other <a href="/facts/Tryptamine/5G31m4BT">tryptamines</a>, <a href="/facts/Amphetamine/yKIpLJ9E">amphetamines</a>, <a href="/facts/Ketamine/BtNSoqvh">ketamine</a>, and <a href="/facts/Phencyclidine/4LaNo5Cl">phencyclidine</a>.<a class="footnote-ref" id="fnref:11" href="#fn:11"><sup>11</sup></a><a class="footnote-ref" id="fnref:12" href="#fn:12"><sup>12</sup></a> </p> <h2 id="pathophysiology">Pathophysiology</h2> <p>Bad trips may cause range of conditions such as <a href="/facts/Psychosis/cVGd7MKK">psychosis</a> and <a href="/facts/Hallucinogen_persisting_perception_disorder/nbGkyhfJ">hallucinogen persisting perception disorder</a> (HPPD).<a class="footnote-ref" id="fnref:13" href="#fn:13"><sup>13</sup></a> </p> <h2 id="perspectives">Perspectives</h2> <h3>Stanislav Grof</h3> <p>Psychiatrist <a href="/facts/Stanislav_Grof/6uLFvQ8u">Stanislav Grof</a> once said in an interview: </p> <blockquote><p>There is a tremendous danger of confusing the inner world with the outer world, so you'll be dealing with your inner realities but at the same time you are not even aware of what's happening, You perceive a sort of distortion of the world out there. So you can end up in a situation where you're weakening the resistances, your conscious is becoming more aware, but you're not really in touch with it properly, you're not really fully experiencing what's there, not seeing it for what it is. You get kind of deluded and caught into this.<a class="footnote-ref" id="fnref:14" href="#fn:14"><sup>14</sup></a></p></blockquote> <p>In a 1975 book, Grof suggested that painful and difficult experiences during a trip could be a result of the mind reliving experiences associated with birth, and that experiences of imprisonment, <a href="/facts/Eschatological/yRyvUt8B">eschatological</a> terror, or suffering far beyond anything imaginable in a normal state, if seen through to conclusion, often resolve into emotional, intellectual and spiritual breakthroughs. From this perspective, Grof suggests that interrupting a bad trip, while initially seen as beneficial, could potentially trap the tripper in unresolved psychological states. Grof also suggests that many cathartic experiences within psychedelic states, while not necessarily crises, may be the effects of consciousness entering a perinatal space.<a class="footnote-ref" id="fnref:15" href="#fn:15"><sup>15</sup></a> </p> <h3>Rick Strassman</h3> <p>Professor of psychiatry <a href="/facts/Rick_Strassman/FIPTKBYM">Rick Strassman</a> is critical of reframing the experience of bad trips as one of "challenging experiences".<a class="footnote-ref" id="fnref:16" href="#fn:16"><sup>16</sup></a> </p> <h2 id="see-also">See also</h2> <ul><li><a href="/facts/Altered_state_of_consciousness/97vjsHXF">Altered state of consciousness</a></li> <li><a href="/facts/Ego_death/UuU2H9cs">Ego death</a></li> <li><a href="/facts/Existential_crisis/yp5GkbdE">Existential crisis</a></li> <li><a href="/facts/Hard_and_soft_drugs/NynGY88V">Hard and soft drugs</a></li> <li><a href="/facts/Harm_reduction/2cAHgTu7">Harm reduction</a></li> <li><a href="/facts/Lucid_dreaming/gBM42ISY">Lucid dreaming</a></li> <li><a href="/facts/Near-death_experience/q8Lv6fyK">Near-death experience</a></li> <li><a href="/facts/Out-of-body_experience/Pp5uSzUj">Out-of-body experience</a></li> <li><a href="/facts/Overdose/Jlo2AX3Y">Overdose</a></li> <li><a href="/facts/Posttraumatic_growth/tk9NEmyV">Posttraumatic growth</a></li> <li><a href="/facts/Posttraumatic_stress_disorder/9etKu7bX">Posttraumatic stress disorder</a></li> <li><a href="/facts/Psychedelic_experience/8uJ4ce7r">Psychedelic experience</a></li> <li><a href="/facts/Psychedelic_therapy/mokV4INC">Psychedelic therapy</a></li> <li><a href="/facts/Psychedelics%2c_dissociatives_and_deliriants/gn35weCu">Psychedelics, dissociatives and deliriants</a></li> <li><a href="/facts/Psychonautics/Aq8cjJzx">Psychonautics</a></li> <li><a href="/facts/Psychosis/cVGd7MKK">Psychosis</a></li> <li><a href="/facts/Recreational_drug_use/eoBD3vKn">Recreational drug use</a></li> <li><a href="/facts/Responsible_drug_use/LNorRq1o">Responsible drug use</a></li> <li><a href="/facts/Sensory_deprivation/63aP6VXn">Sensory deprivation</a></li> <li><a href="/facts/Set_and_setting/egeTaDDo">Set and setting</a></li> <li><a href="/facts/Spiritual_crisis/0MYGtW1n">Spiritual crisis</a></li></ul> <h2 id="external-links">External links</h2> <ul><li><a href="http://www.psychedelic-library.org/grof2.htm">Crisis Intervention in Situations Related to Unsupervised Use of Psychedelics</a></li> <li><a href="http://www.erowid.org/psychoactives/faqs/psychedelic_crisis_faq.shtml">Psychedelic Crisis FAQ: Helping someone through a bad trip, psychic crisis, or spiritual crisis</a></li> <li><a href="http://www.maps.org/resources/responding_to_difficult_psychedelic_experiences/">Psychedelic Harm Reduction</a> <a href="https://web.archive.org/web/20140604020401/http://www.maps.org/resources/responding_to_difficult_psychedelic_experiences/">Archived</a> 2014-06-04 at the <a href="/facts/Wayback_Machine/nmQ3a6JC">Wayback Machine</a></li> <li><a href="https://vimeo.com/15960576">Psychedelic Harm Reduction and Policy</a> lecture in the Psychedelic Science in the 21st Century conference in 2010.</li> <li><a href="https://vimeo.com/16702478">Psychedelics in the Psychiatric ER - Julie Holland, M.D.</a> lecture in the Psychedelic Science in the 21st Century conference in 2010.</li> <li><a href="https://archive.today/20130122013826/http://www.drugs-wiki.com/forum/showwiki.php?title=The_psychedelic_crisis:_bad_trip">The Psychedelic crisis (bad trip) entry at Drugs-Wiki</a></li></ul> <h2 id="references">References</h2> <ol> <li id="fn:1"><p>Gashi, Liridona; Sandberg, Sveinung; Pedersen, Willy (2021). "Making "bad trips" good: How users of psychedelics narratively transform challenging trips into valuable experiences". International Journal of Drug Policy. 87: 102997. doi:10.1016/j.drugpo.2020.102997. hdl:10852/81144. ISSN 0955-3959. PMID 33080454. <a href="https://doi.org/10.1016/j.drugpo.2020.102997" target="_blank">https://doi.org/10.1016/j.drugpo.2020.102997</a> <a href="#fnref:1" class="footnote-back-ref">↩</a></p></li> <li id="fn:2"><p>Grof, Stanislav (2008). LSD Psychotherapy. Multidisciplinary Association for Psychedelic Studies. ISBN 978-0-9798622-0-5. <a href="978-0-9798622-0-5" target="_blank">978-0-9798622-0-5</a> <a href="#fnref:2" class="footnote-back-ref">↩</a></p></li> <li id="fn:3"><p>Johnson, Matthew W.; Richards, William A.; Griffiths, Roland R. (2008). "Human Hallucinogen Research: Guidelines for Safety". Journal of Psychopharmacology. 22 (6): 603–620. doi:10.1177/0269881108093587. PMC 3056407. PMID 18593734. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056407" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056407</a> <a href="#fnref:3" class="footnote-back-ref">↩</a></p></li> <li id="fn:4"><p>Gashi, Liridona; Sandberg, Sveinung; Pederson, Willy (2021). "Making "bad trips" good: How users of psychedelics narratively transform challenging trips into valuable experiences". International Journal of Drug Policy. 87: 102997. doi:10.1016/j.drugpo.2020.102997. hdl:10852/81144. PMID 33080454. S2CID 224821288. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:4" class="footnote-back-ref">↩</a></p></li> <li id="fn:5"><p>Johnson, Matthew W.; Richards, William A.; Griffiths, Roland R. (2008). "Human Hallucinogen Research: Guidelines for Safety". Journal of Psychopharmacology. 22 (6): 603–620. doi:10.1177/0269881108093587. PMC 3056407. PMID 18593734. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056407" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056407</a> <a href="#fnref:5" class="footnote-back-ref">↩</a></p></li> <li id="fn:6"><p>Grof, Stanislav (2008). LSD Psychotherapy. Multidisciplinary Association for Psychedelic Studies. ISBN 978-0-9798622-0-5. <a href="978-0-9798622-0-5" target="_blank">978-0-9798622-0-5</a> <a href="#fnref:6" class="footnote-back-ref">↩</a></p></li> <li id="fn:7"><p>Gashi, Liridona; Sandberg, Sveinung; Pederson, Willy (2021). "Making "bad trips" good: How users of psychedelics narratively transform challenging trips into valuable experiences". International Journal of Drug Policy. 87: 102997. doi:10.1016/j.drugpo.2020.102997. hdl:10852/81144. PMID 33080454. S2CID 224821288. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:7" class="footnote-back-ref">↩</a></p></li> <li id="fn:8"><p>Barrett, FS; Bradstreet, MP; Leoutsakos, JS; Johnson, MW; Griffiths, RR (December 2016). "The Challenging Experience Questionnaire: Characterization of challenging experiences with psilocybin mushrooms". Journal of Psychopharmacology. 30 (12): 1279–1295. doi:10.1177/0269881116678781. PMC 5549781. PMID 27856683. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549781" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549781</a> <a href="#fnref:8" class="footnote-back-ref">↩</a></p></li> <li id="fn:9"><p>van Amsterdam, Jan; Opperhuizen, Antoon; van den Brink, Wim (2011). "Harm potential of magic mushroom use: A review". Regulatory Toxicology and Pharmacology. 59 (3): 423–429. doi:10.1016/j.yrtph.2011.01.006. PMID 21256914. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:9" class="footnote-back-ref">↩</a></p></li> <li id="fn:10"><p>van Amsterdam, Jan; Opperhuizen, Antoon; van den Brink, Wim (2011). "Harm potential of magic mushroom use: A review". Regulatory Toxicology and Pharmacology. 59 (3): 423–429. doi:10.1016/j.yrtph.2011.01.006. PMID 21256914. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:10" class="footnote-back-ref">↩</a></p></li> <li id="fn:11"><p>Giannini, A. James; Underwood, Ned A.; Condon, Maggie (2000). "Acute Ketamine Intoxication Treated by Haloperidol". American Journal of Therapeutics. 7 (6): 389–91. doi:10.1097/00045391-200007060-00008. PMID 11304647. <a href="/wiki/American_Journal_of_Therapeutics" target="_blank">/wiki/American_Journal_of_Therapeutics</a> <a href="#fnref:11" class="footnote-back-ref">↩</a></p></li> <li id="fn:12"><p>"Sage Journals". Archived from the original on 2014-08-24. Retrieved 2018-03-27. <a href="https://web.archive.org/web/20140824075401/http://online.sagepub.com/site/moved?view=long&pmid=6725621" target="_blank">https://web.archive.org/web/20140824075401/http://online.sagepub.com/site/moved?view=long&pmid=6725621</a> <a href="#fnref:12" class="footnote-back-ref">↩</a></p></li> <li id="fn:13"><p>Bracco, Jessica (May 2019). "The United States Print Media and its War on Psychedelic Research in the 1960s". The Exposition. 5 (1): 9–10. <a href="https://digitalcommons.buffalostate.edu/exposition/vol5/iss1/2/" target="_blank">https://digitalcommons.buffalostate.edu/exposition/vol5/iss1/2/</a> <a href="#fnref:13" class="footnote-back-ref">↩</a></p></li> <li id="fn:14"><p>"Beyond Psychotic Experience - Stan Grof interviewed by Jon Atkinson". Archived from the original on 2011-09-27. Retrieved 2011-04-12. <a href="https://web.archive.org/web/20110927122540/http://www.lycaeum.org/leda/docs/16869.shtml?ID=16869" target="_blank">https://web.archive.org/web/20110927122540/http://www.lycaeum.org/leda/docs/16869.shtml?ID=16869</a> <a href="#fnref:14" class="footnote-back-ref">↩</a></p></li> <li id="fn:15"><p>Grof, Stanislav (1975). realms of the human unconscious - Observations from LSD research. souvenir press. pp. 95–153. ISBN 0-285-64882-9. <a href="0-285-64882-9" target="_blank">0-285-64882-9</a> <a href="#fnref:15" class="footnote-back-ref">↩</a></p></li> <li id="fn:16"><p>"Misguided Mainstreaming of Psychedelic Drugs: Challenging Experiences". Rick Strassman MD. 25 October 2017. <a href="https://www.rickstrassman.com/misguided-mainstreaming-of-psychedelic-drugs-challenging-experiences/" target="_blank">https://www.rickstrassman.com/misguided-mainstreaming-of-psychedelic-drugs-challenging-experiences/</a> <a href="#fnref:16" class="footnote-back-ref">↩</a></p></li> </ol>