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Bombesin
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<h2 id="receptors">Receptors</h2> <p>The <a href="/facts/Anuran/IxYhbeda">anuran</a> BB4 receptor <a href="/facts/Sequence_homology/mCIVStrA">homologue</a> is termed frog BB4 (fBB4).<a class="footnote-ref" id="fnref:7" href="#fn:7"><sup>7</sup></a> Iwabuchi <i>et al.</i> 2003 discovered a <a href="/facts/Chicken/RD2eTd83">chicken</a> (<i>Gallus domesticus</i>) receptor which is homologous to both the mammalian BB3 and fBB4 and so they named it chBRS-3.5.<a class="footnote-ref" id="fnref:8" href="#fn:8"><sup>8</sup></a> </p> <h2 id="effects">Effects</h2> <p>Erspamer 1988 finds bombesin has a similar effect on the chicken to ranatensin, unreliably increasing or decreasing blood pressure.<a class="footnote-ref" id="fnref:9" href="#fn:9"><sup>9</sup></a> </p> <h2 id="see-also">See also</h2> <ul><li><a href="/facts/Gastrin-releasing_peptide/TKJssgWn">Gastrin-releasing peptide</a></li> <li><a href="/facts/Neuromedin_B/MNQQc4sW">Neuromedin B</a></li> <li><a href="/facts/Neuromedin_U/HKyRaEpE">Neuromedin U</a></li></ul> <h2 id="references">References</h2> <ol> <li id="fn:1"><p>Gonzalez N, Moody TW, Igarashi H, Ito T, Jensen RT (February 2008). "Bombesin-related peptides and their receptors: recent advances in their role in physiology and disease states". Current Opinion in Endocrinology, Diabetes and Obesity. 15 (1): 58–64. doi:10.1097/MED.0b013e3282f3709b. PMC 2631407. PMID 18185064. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631407" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631407</a> <a href="#fnref:1" class="footnote-back-ref">↩</a></p></li> <li id="fn:2"><p>Anastasi, A.; Erspamer, Vittorio; Bucci, M. (1971). "Isolation and structure of bombesin and alytesin, two analogous active peptides from the skin of the european amphibians Bombina and Alytes". Experientia. 27 (2). Springer: 166–167. doi:10.1007/bf02145873. ISSN 0014-4754. PMID 5544731. S2CID 30779940.Verkhratsky, Alexei; Nedergaard, Maiken (2018-01-01). "Physiology of Astroglia". Physiological Reviews. 98 (1). American Physiological Society: 239–389. doi:10.1152/physrev.00042.2016. ISSN 0031-9333. PMC 6050349. PMID 29351512.M., H. (1972). "Toxicon Reviews". Toxicon. 10 (2). International Society on Toxinology + Brazilian Society of Toxinology + North American Society of Toxinology (Elsevier): 189. doi:10.1016/0041-0101(72)90248-6. ISSN 0041-0101. PMID 5544731. S2CID 32711539.Daniel, Edwin E., ed. (2019-08-15). Neuropeptide Function in the Gastrointestinal Tract. CRC Press. ISBN 978-0-429-28576-9. OCLC 1112671803. <a href="978-0-429-28576-9" target="_blank">978-0-429-28576-9</a> <a href="#fnref:2" class="footnote-back-ref">↩</a></p></li> <li id="fn:3"><p>Jensen, R. T.; Battey, J. F.; Spindel, E. R.; Benya, R. V. (2007-11-30). "International Union of Pharmacology. LXVIII. Mammalian Bombesin Receptors: Nomenclature, Distribution, Pharmacology, Signaling, and Functions in Normal and Disease States". Pharmacological Reviews. 60 (1). American Society for Pharmacology & Experimental Therapeutics (ASPET): 1–42. doi:10.1124/pr.107.07108. ISSN 0031-6997. PMC 2517428. PMID 18055507. NIHMSID 45053. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2517428" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2517428</a> <a href="#fnref:3" class="footnote-back-ref">↩</a></p></li> <li id="fn:4"><p>Weber HC (February 2009). "Regulation and signaling of human bombesin receptors and their biological effects". Current Opinion in Endocrinology, Diabetes and Obesity. 16 (1): 66–71. doi:10.1097/med.0b013e32831cf5aa. PMID 19115523. S2CID 45482442. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:4" class="footnote-back-ref">↩</a></p></li> <li id="fn:5"><p>Yamada K, Wada E, Wada K (November 2000). "Bombesin-like peptides: studies on food intake and social behaviour with receptor knock-out mice". Annals of Medicine. 32 (8): 519–29. doi:10.3109/07853890008998831. PMID 11127929. S2CID 24431961. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:5" class="footnote-back-ref">↩</a></p></li> <li id="fn:6"><p>Ohlsson B, Fredäng N, Axelson J (December 1999). "The effect of bombesin, cholecystokinin, gastrin, and their antagonists on proliferation of pancreatic cancer cell lines". Scandinavian Journal of Gastroenterology. 34 (12): 1224–9. doi:10.1080/003655299750024742. PMID 10636070. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:6" class="footnote-back-ref">↩</a></p></li> <li id="fn:7"><p>Jensen, R. T.; Battey, J. F.; Spindel, E. R.; Benya, R. V. (2007-11-30). "International Union of Pharmacology. LXVIII. Mammalian Bombesin Receptors: Nomenclature, Distribution, Pharmacology, Signaling, and Functions in Normal and Disease States". Pharmacological Reviews. 60 (1). American Society for Pharmacology & Experimental Therapeutics (ASPET): 1–42. doi:10.1124/pr.107.07108. ISSN 0031-6997. PMC 2517428. PMID 18055507. NIHMSID 45053. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2517428" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2517428</a> <a href="#fnref:7" class="footnote-back-ref">↩</a></p></li> <li id="fn:8"><p>Jensen, R. T.; Battey, J. F.; Spindel, E. R.; Benya, R. V. (2007-11-30). "International Union of Pharmacology. LXVIII. Mammalian Bombesin Receptors: Nomenclature, Distribution, Pharmacology, Signaling, and Functions in Normal and Disease States". Pharmacological Reviews. 60 (1). American Society for Pharmacology & Experimental Therapeutics (ASPET): 1–42. doi:10.1124/pr.107.07108. ISSN 0031-6997. PMC 2517428. PMID 18055507. NIHMSID 45053. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2517428" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2517428</a> <a href="#fnref:8" class="footnote-back-ref">↩</a></p></li> <li id="fn:9"><p>Erspamer, Vittorio (1988). "Discovery, Isolation, and Characterization of Bombesin-like Peptides". Part I. Chemistry and Molecular Biology of Bombesin-like Peptides. Annals of the New York Academy of Sciences. 547 (1 Bombesin-Like). NYAS (WB): 3–9. Bibcode:1988NYASA.547....3E. doi:10.1111/j.1749-6632.1988.tb23870.x. ISSN 0077-8923. PMID 3071223. S2CID 83974453.Moreno, Paola; Mantey, Samuel A.; Nakamura, Taichi; Nuche-Berenguer, Bernardo; Moody, Terry W.; Coy, David H.; Jensen, Robert T. (2001-09-06). "Insights into Bombesin receptors and ligands: Highlighting recent advances". Peptides. 72. Elsevier: 128–144. doi:10.1016/j.peptides.2015.04.026. PMC 4641779. PMID 25976083. NIHMSID 697823.Daniel, Edwin E., ed. (2019-08-15). Neuropeptide Function in the Gastrointestinal Tract. CRC Press. ISBN 978-0-429-28576-9. OCLC 1112671803.Jensen, R. T.; Battey, J. F.; Spindel, E. R.; Benya, R. V. (2007-11-30). "International Union of Pharmacology. LXVIII. Mammalian Bombesin Receptors: Nomenclature, Distribution, Pharmacology, Signaling, and Functions in Normal and Disease States". Pharmacological Reviews. 60 (1). American Society for Pharmacology & Experimental Therapeutics (ASPET): 1–42. doi:10.1124/pr.107.07108. ISSN 0031-6997. PMC 2517428. PMID 18055507. NIHMSID 45053. <a href="978-0-429-28576-9" target="_blank">978-0-429-28576-9</a> <a href="#fnref:9" class="footnote-back-ref">↩</a></p></li> </ol>