Seidel test

<h2 id="name">Name</h2>
<p>The Seidel test was first described by German <a href="/facts/Ophthalmologist/024hdTWF">ophthalmologist</a> <a href="/facts/Erich_Seidel_(ophthalmologist)/JS2VY9QV">Erich Seidel</a> in 1921.<a class="footnote-ref" id="fnref:4" href="#fn:4"><sup>4</sup></a>
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<h2 id="procedure">Procedure</h2>
<p>A <a href="/facts/Fluorescein/8E4xH5at">fluorescein</a> strip containing 10% fluorescein is applied topically to the affected area, without applying pressure on the eye due to the risk of tissue extrusion.<a class="footnote-ref" id="fnref:5" href="#fn:5"><sup>5</sup></a> The fluorescein is examined with a <a href="/facts/Cobalt_blue/rVImlMf3">cobalt blue</a> filter.  At this point, the fluorescein appears green in color.  Any changes in color or surface of the fluorescence area indicate the presence of corneal leakage. The test is contraindicated in obvious globe rupture, Full-thickness eye laceration, and fluorescein hypersensitivity.<a class="footnote-ref" id="fnref:6" href="#fn:6"><sup>6</sup></a>
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<h2 id="results-of-the-test">Results of the test</h2>
<p>If the <a href="/facts/Fluorescein/8E4xH5at">fluorescein</a> strip turns pale upon application to the corneal surface, the person tests positive for the corneal deformity they are being tested for.  The change in the color of the fluorescein strip is due to dilution of fluorescein caused by the aqueous leakage in the cornea.
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<h2 id="external-links">External links</h2>
<ul><li><a href="http://www.fpnotebook.com/Eye/Exam/SdlTst.htm">Family Practice Notebook</a></li>
<li><a href="http://www.whonamedit.com/doctor.cfm/3382.html">Who Named It?</a></li>
<li><a href="http://emedicine.medscape.com/article/1230457-diagnosis">WebMD</a></li>
<li><a href="https://www.ncbi.nlm.nih.gov/pubmed/550919">US National Library of Medicine, PubMed</a></li>
<li><a href="http://www.patient.co.uk/showdoc/40000854/">Patient UK</a></li></ul>

<h2 id="references">References</h2>

<ol>
<li id="fn:1"><p>Campbell, Taylor D.; Gnugnoli, David M. (2021). "Seidel Test". StatPearls. StatPearls Publishing. PMID 31082063. <a href="https://www.ncbi.nlm.nih.gov/books/NBK541019/" target="_blank">https://www.ncbi.nlm.nih.gov/books/NBK541019/</a> <a href="#fnref:1" class="footnote-back-ref">↩</a></p></li>
<li id="fn:2"><p>Campbell, Taylor D.; Gnugnoli, David M. (2021). "Seidel Test". StatPearls. StatPearls Publishing. PMID 31082063. <a href="https://www.ncbi.nlm.nih.gov/books/NBK541019/" target="_blank">https://www.ncbi.nlm.nih.gov/books/NBK541019/</a> <a href="#fnref:2" class="footnote-back-ref">↩</a></p></li>
<li id="fn:3"><p>Campbell, Taylor D.; Gnugnoli, David M. (2021). "Seidel Test". StatPearls. StatPearls Publishing. PMID 31082063. <a href="https://www.ncbi.nlm.nih.gov/books/NBK541019/" target="_blank">https://www.ncbi.nlm.nih.gov/books/NBK541019/</a> <a href="#fnref:3" class="footnote-back-ref">↩</a></p></li>
<li id="fn:4"><p>Campbell, Taylor D.; Gnugnoli, David M. (2021). "Seidel Test". StatPearls. StatPearls Publishing. PMID 31082063. <a href="https://www.ncbi.nlm.nih.gov/books/NBK541019/" target="_blank">https://www.ncbi.nlm.nih.gov/books/NBK541019/</a> <a href="#fnref:4" class="footnote-back-ref">↩</a></p></li>
<li id="fn:5"><p>"Seidel Test - EyeWiki". eyewiki.aao.org. <a href="https://eyewiki.aao.org/Seidel_Test" target="_blank">https://eyewiki.aao.org/Seidel_Test</a> <a href="#fnref:5" class="footnote-back-ref">↩</a></p></li>
<li id="fn:6"><p>Campbell, Taylor D.; Gnugnoli, David M. (2021). "Seidel Test". StatPearls. StatPearls Publishing. PMID 31082063. <a href="https://www.ncbi.nlm.nih.gov/books/NBK541019/" target="_blank">https://www.ncbi.nlm.nih.gov/books/NBK541019/</a> <a href="#fnref:6" class="footnote-back-ref">↩</a></p></li>
</ol>

Seidel test open-in-new

Seidel test