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Rabbitpox
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<h2 id="history">History</h2> <p>Rabbitpox has not been recognised in wild rabbits, however a few outbreaks have been reported in the USA since 1930.<a class="footnote-ref" id="fnref:5" href="#fn:5"><sup>5</sup></a> </p> <h2 id="symptoms">Symptoms</h2> <ul><li>Pox lesions may or may not be present on the skin.</li> <li>Most rabbits develop a fever and nasal discharge.</li> <li>The mortality varies but is always high.</li> <li>The most characteristic lesions seen at <a href="/facts/Necropsy/GzSXuCH2">necropsy</a> are a skin rash, <a href="/facts/Subcutis/EPYjXN3G">subcutaneous</a> <a href="/facts/Edema/Q6MI3KdH">edema</a>, and edema of the mouth and other body openings.</li></ul> <h2 id="infection">Infection</h2> <p>Rabbitpox virus is a highly infectious airborne agent, which spreads very rapidly through laboratories which contain rabbits causing a high rate of mortality. Because of the edematous condition, “poxless” rabbitpox may be confused with <a href="/facts/Myxomatosis/whdRexmF">myxomatosis</a>. The virus may be isolated or the infection diagnosed serologically by methods appropriate to <a href="/facts/Vaccinia/jSgHWq2k">vaccinia</a>. Rabbitpox virus is closely related immunologically to vaccinia virus, consequently rabbits that have been inoculated with the <a href="/facts/Smallpox/cxNeetP4">smallpox</a> (vaccinia virus) vaccine have immunity against rabbitpox. </p> <h2 id="danger-to-humans">Danger to humans</h2> <p>Rabbitpox virus does not infect humans. </p> <h2 id="references">References</h2> <ol> <li id="fn:1"><p>"Medical Dictionary - 'rabbitpox virus'". mediLexicon. Retrieved 2007-04-03. <a href="http://www.medilexicon.com/medicaldictionary.php?t=99011" target="_blank">http://www.medilexicon.com/medicaldictionary.php?t=99011</a> <a href="#fnref:1" class="footnote-back-ref">↩</a></p></li> <li id="fn:2"><p>Adams MM, Rice AD, Moyer RW (October 2007). "Rabbitpox virus and vaccinia virus infection of rabbits as a model for human smallpox". Journal of Virology. 81 (20): 11084–95. doi:10.1128/JVI.00423-07. PMC 2045566. PMID 17686856. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2045566" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2045566</a> <a href="#fnref:2" class="footnote-back-ref">↩</a></p></li> <li id="fn:3"><p>C. Upton; Chen, N; Roper, RL; Feng, Z; Hunter, A; Danila, M; Lefkowitz, EJ; Buller, RM; Upton, C (August 12, 2005). "Complete coding sequences of the rabbitpox virus genome" (PDF). Journal of General Virology. 86 (Pt 11): 2969–2977. doi:10.1099/vir.0.81331-0. PMID 16227218. Retrieved 2007-04-03. <a href="http://vir.sgmjournals.org/cgi/reprint/86/11/2969.pdf" target="_blank">http://vir.sgmjournals.org/cgi/reprint/86/11/2969.pdf</a> <a href="#fnref:3" class="footnote-back-ref">↩</a></p></li> <li id="fn:4"><p>"Rabbitpox". The Merck Veterinary Manual. Archived from the original on 2007-04-16. Retrieved 2007-04-03. <a href="https://web.archive.org/web/20070416030732if_/http://www.merckvetmanual.com:80/mvm/index.jsp?cfile=htm/bc/171327.htm" target="_blank">https://web.archive.org/web/20070416030732if_/http://www.merckvetmanual.com:80/mvm/index.jsp?cfile=htm/bc/171327.htm</a> <a href="#fnref:4" class="footnote-back-ref">↩</a></p></li> <li id="fn:5"><p>Merck Veterinary Manual <a href="http://www.merckvetmanual.com/mvm/index.jsp?cfile=htm/bc/171327.htm" target="_blank">http://www.merckvetmanual.com/mvm/index.jsp?cfile=htm/bc/171327.htm</a> <a href="#fnref:5" class="footnote-back-ref">↩</a></p></li> </ol>