Locsin's breakthrough role came as the avian-human hybrid protagonist in the fantasy action series Mulawin (2004). GMA Network executive Redgie Magno initially approached Maxene Magalona for the part, but offered Locsin the role at Magalona's suggestion. Dominic Zapata, the show's director, intended the concept of mythology to be a "break from Tagalized soaps", but also kept its "novelty" focused on the lead characters. The following year, Locsin starred as the titular superhero in the Ravelo Komiks Universe series Darna (2005), based on Mars Ravelo's comics superheroine of the same name. Locsin was initially hesitant about the part because it required her to drop out of Mulawin, and she felt the series would end prematurely if she left. Locsin agreed to the project after network executives convinced her to take the part. She trained in karate, wushu, and street fighting to prepare. The series garnered positive reviews, with praise for Locsin's portrayal; Nestor Torre Jr. of the Philippine Daily Inquirer described the production as modern and trailblazing, and commended Locsin's "strong presence". Similarly, Pepe Diokno, also from the Philippine Daily Inquirer, wrote that "the [show's] success can be attributed to [Locsin], as she attracts every block and wing of Pinoy society." During its premiere, Darna received the highest Nielsen ratings for a Filipino television series pilot episode with a reported 47.1 percent viewership. Later that year, Locsin reprised the role of Alwina in Mulawin's film adaptation.
Locsin portrayed the role of Lia Ortega, the daughter of her lycan character in the second installment of the Lobo series, Imortal (2010). In a review of the show, Bayani San Diego of the Philippine Daily Inquirer drew similarities between Imortal's vampire and werewolf fiction and that of The Twilight Saga, he added that "creatures of the dark are all the rage today, given the popularity of True Blood and The Vampire Diaries." Journalist Earl Villanueva, however, commended Locsin's character and storyline for its "easy transition into a logical sequel", and said the series "seems to be on the right track". Locsin's only film appearance in 2011 was in the star-crossed romantic drama In the Name of Love with director Olivia Lamasan, whose collaboration she found gratifying: "I've learned a lot, especially as to how film acting should be done ... How you use your eyes, your position, and how you maximize camera angles ... I didn't know those things before." To prepare for the role of a courtesan, she learned different styles of ballroom dances and trained in pole dance for three months. Critic Julia Allende praised her portrayal, and pairing with Aga Muhlach, describing it as "the most daring she [Locsin] has ever played" and deemed it a "beautifully nuanced performance". Locsin won the Star Award for Best Actress and the Box Office Entertainment Award for Film Actress of the Year for her role. Later that year, Locsin co-starred with Vhong Navarro in the sitcom Toda Max.
After a one-year absence on screen, Locsin appeared in three productions in 2016. Her first release was Joyce Bernal's Everything About Her, a comedy drama co-starring Vilma Santos. Stephanie Mayo of the Daily Tribune termed Locsin's and Santos's portrayals as "effortless, natural, and searing"; The Philippine Star lauded the cast's acting as "compelling" and called the film a "finely-crafted family drama". At the Asia-Pacific Film Festival, Locsin won Best Supporting Actress for her performance in the film. She then served as a judge on the fifth season of the reality talent competition show Pilipinas Got Talent, based on the original British show franchise. Her final appearance that year was in The Third Party, a comedy that depicts the complex relationship in a throuple. Asilo dismissed the film as "more derivative than inventive" and stated that Locsin is "weighed down by her pushed, staccato delivery, and relies too much on knee-jerk realizations". Philbert Dy of ClickTheCity.com wrote, "[The film] seems to make its characters cry in lieu of telling their stories, or letting them hash out the complexity of what they're feeling."
Locsin has advocated for children's education. She has funded scholarships and personally contributed over US$300,000 to the cause. A vocal supporter of women's rights and gender equality, she has spoken about the stigma women face, "We're still in that stage. It is upsetting that, for me, we still lack efforts to prevent that [stigma] especially in our workplace, to have a comfortable and safe place for women." She also actively supports LGBT rights and describes herself as a "proud ally". In June 2015, she voiced her approval of same-sex marriage, stating, "We should show respect, sensitivity, & compassion to one another ... I'm not going to deny my LGBT friends the protection that straight people get ... think of insurances, healthcare". Locsin has participated in a campaign against domestic violence. In 2020, she partnered with the United States Agency for International Development (USAID) and Lunas Collective, a hotline for survivors and victims of domestic abuse, to raise awareness and promote international cooperation.
Locsin has received wide recognition for her humanitarian work. In December 2019, Forbes magazine named her one of Asia's Heroes of Philanthropy for a decade of contributions to various philanthropic causes, and she was appointed an Ambassador for Peace and a Humanitarian Advocate by the Gawad Filipino Awards. She was recognized by Tatler magazine as one of Asia's Leaders of Tomorrow in the publication's annual Gen T list in October 2020. The following year, Locsin received the inaugural Spirit of Philanthropy Award from the Philippine Red Cross.
Locsin is often regarded by critics as one of the "most sought after leading ladies" on film and television in the Philippines, and has been cited as one of the "greatest movie actresses" in the last decade by Yes! magazine. She has appeared in a range of film genres, but generally played roles in mainstream productions. Media critic James Anarcon praised her for being the rare actress who "allowed herself to be deglamorized". Metro magazine noted that as a young actress on the teen series Click, Locsin plays the "boyish but charming girl-next-door, which is not unlike the star's real down-to-earth persona". Locsin has said she bases her acting approach on her observations of people around her: "I guess part of being an actor is learning how to be sensitive to the needs of people ... I always do research before taking on a role. As a result, I become more aware of what people outside my line of work are going through."
Early in her career, Locsin specialized in portraying heroines and mythological characters in fantasy and supernatural genres. Nathalie Tomada of The Philippine Star wrote, "No other actress but [Locsin], who first shot to fame through fantaseryes, can claim a record of strong and kickass female roles as extensive as hers." An interest in portraying an "action figure that departs from the sexy stereotype" has led Locsin to these roles. Locsin asserted, "You should not be limited to certain things". Meanwhile, writer Rommel Llanes dispelled the perception that portraying superheroes could hurt an actor's career, stating that Locsin is one of those exceptions. Her Darna co-star Celia Rodriguez called her "the best ... bar none", saying, "She is perfect for the role. She had the figure for it. She was fearless. She refused to have a double even when portions of her body were badly hurt by the harness." Similarly, The Philippine Star considered Locsin as the "most fitting actress to have slipped on the iconic red suit and crest". Cathy Garcia-Molina, who directed Locsin in La Luna Sangre, and Robin Padilla, her co-star in Asian Treasures, commended her for doing her own stunts.
The media has described Locsin as the "real-life Darna" and an "angel in disguise" for her volunteerism and charitable work. Writing for Mega magazine, Rose Estellas lauded her for having the "heart to serve others" and for using her "influence and platform to continuously help and change the lives of Filipinos". Commenting on her off-screen persona, journalist Gerry Plaza wrote that she is "simple, unfiltered, unassuming". Locsin said, "I have no hero complex. I just believe that when there's a will there's a way. I will continue to help in different ways. Helping doesn't always have to involve giving away money."
At the end of March 2022, Locsin opened up that she and husband were not planning on having a baby yet as she was still treating a health problem with her thyroid.
Locsin has been named Best Supporting Actress at the Asia-Pacific Film Festival for Everything About Her. For her role in One More Try, she was awarded the Box Office Entertainment, FAMAS, Luna and Star Award for Best Actress. She received a Box Office Entertainment and Star Award for In the Name of Love. In addition, for her role in the television series The General's Daughter, she received a Star Award for Best Actress, and won TV Actress of the Year and Best Acting Ensemble in a Drama Series at the Box Office Entertainment Awards.
Locsin went into hiatus since 2022.
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Ravelo Komiks Universe is a Filipino media franchise and shared universe centered on a series of superhero films and television shows based on characters that appear in Philippine comic books published by Mars Ravelo.[19] /wiki/Media_franchise
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Baldono, Krista (April 23, 2019). "Kapamilya Spotlight: Angel Locsin and her highly acclaimed TV journey". ABS-CBN Entertainment. Archived from the original on September 21, 2021. Retrieved May 21, 2022. https://ent.abs-cbn.com/thegeneralsdaughter/videos/kapamilya-spotlight-angel-locsin-and-her-highly-a-158
Maglipon, Jo-An (May 2, 2021). "15 Greatest Movie Actresses in Leading Roles, 2000-2020" (in Tagalog). Philippine Entertainment Portal. Archived from the original on May 21, 2022. Retrieved May 21, 2022. https://www.pep.ph/guide/movies/157987/15-greatest-movie-actresses-in-leading-roles-no-6-10-a3898-a710-20210502-lfrm4
Maglipon, Jo-An (May 2, 2021). "15 Greatest Movie Actresses in Leading Roles, 2000-2020" (in Tagalog). Philippine Entertainment Portal. Archived from the original on May 21, 2022. Retrieved May 21, 2022. https://www.pep.ph/guide/movies/157987/15-greatest-movie-actresses-in-leading-roles-no-6-10-a3898-a710-20210502-lfrm4
Maglipon, Jo-An (May 2, 2021). "15 Greatest Movie Actresses in Leading Roles, 2000-2020" (in Tagalog). Philippine Entertainment Portal. Archived from the original on May 21, 2022. Retrieved May 21, 2022. https://www.pep.ph/guide/movies/157987/15-greatest-movie-actresses-in-leading-roles-no-6-10-a3898-a710-20210502-lfrm4
Maglipon, Jo-An (May 2, 2021). "15 Greatest Movie Actresses in Leading Roles, 2000-2020" (in Tagalog). Philippine Entertainment Portal. Archived from the original on May 21, 2022. Retrieved May 21, 2022. https://www.pep.ph/guide/movies/157987/15-greatest-movie-actresses-in-leading-roles-no-6-10-a3898-a710-20210502-lfrm4
"Metro Society Most Influential: Online Sensations (Angel Locsin)". Metro. March 3, 2018. Archived from the original on October 19, 2020. Retrieved May 21, 2022. https://metro.style/people/society-personalities/metrosocietymostinfluential-angel-locsin/8605
Cruz, Marinel (August 29, 2020). "Angel on motive for helping others: Not politics, but obligation as a human being and as a Filipino". Philippine Daily Inquirer. Archived from the original on December 21, 2020. Retrieved May 21, 2022. https://entertainment.inquirer.net/388823/angel-on-motive-for-helping-others-not-politics-but-obligation-as-a-human-being-and-as-a-filipino
Tomada, Nathalie (January 13, 2019). "Angel back in fighting form". The Philippine Star. Archived from the original on July 10, 2022. Retrieved May 19, 2022. https://www.philstar.com/entertainment/2019/01/13/1884502/angel-back-fighting-form
"Metro Society Most Influential: Online Sensations (Angel Locsin)". Metro. March 3, 2018. Archived from the original on October 19, 2020. Retrieved May 21, 2022. https://metro.style/people/society-personalities/metrosocietymostinfluential-angel-locsin/8605
Tomada, Nathalie (January 13, 2019). "Angel back in fighting form". The Philippine Star. Archived from the original on July 10, 2022. Retrieved May 19, 2022. https://www.philstar.com/entertainment/2019/01/13/1884502/angel-back-fighting-form
Tomada, Nathalie (January 13, 2019). "Angel back in fighting form". The Philippine Star. Archived from the original on July 10, 2022. Retrieved May 19, 2022. https://www.philstar.com/entertainment/2019/01/13/1884502/angel-back-fighting-form
Tomada, Nathalie (January 13, 2019). "Angel back in fighting form". The Philippine Star. Archived from the original on July 10, 2022. Retrieved May 19, 2022. https://www.philstar.com/entertainment/2019/01/13/1884502/angel-back-fighting-form
Maglipon, Jo-An (May 2, 2021). "15 Greatest Movie Actresses in Leading Roles, 2000-2020" (in Tagalog). Philippine Entertainment Portal. Archived from the original on May 21, 2022. Retrieved May 21, 2022. https://www.pep.ph/guide/movies/157987/15-greatest-movie-actresses-in-leading-roles-no-6-10-a3898-a710-20210502-lfrm4
Lo, Ricky (June 20, 2017). "Celia: Angel Locsin is the best Darna". The Philippine Star. Archived from the original on August 27, 2019. Retrieved May 21, 2022. https://www.philstar.com/entertainment/2017/06/20/1711943/celia-angel-locsin-best-darna
Tomada, Nathalie (April 3, 2006). "Angel's beauty secrets". The Philippine Star. Archived from the original on May 22, 2022. Retrieved May 21, 2022. https://www.philstar.com/cebu-entertainment/2006/04/03/329653/angels-beauty-secrets
"Direk Cathy, inaming pinigilan si Angel na gawin ang stunts sa 'La Luna Sangre'" (in Tagalog). ABS-CBN Entertainment. June 14, 2017. Archived from the original on May 22, 2022. Retrieved May 21, 2022. https://ent.abs-cbn.com/videos/03061417-direk-cathy-inaming-pinigilan-si-angel-na-gawin-ang-stunts-sa-la-luna-sangre-233481
Valera, Nini (September 19, 2006). "Too young for love? No one is, says Robin Padilla, not even Angel". Philippine Daily Inquirer. Archived from the original on July 10, 2022. Retrieved May 21, 2022. https://books.google.com/books?id=4KVjAAAAIBAJ&dq=angel+locsin+praise+robin+padilla&pg=PA38&article_id=1800,21697859
Cruz, Marinel (June 18, 2020). "Angel Locsin balks at 'real-life Darna' title: I have no hero complex". Philippine Daily Inquirer. Archived from the original on February 25, 2022. Retrieved May 21, 2022. https://entertainment.inquirer.net/379621/angel-locsin-balks-at-real-life-darna-title-i-have-no-hero-complex
Villanueva, Brooke (April 19, 2022). "'Real-life Darna' Angel Locsin flies to Leyte to personally help Agaton evacuees". The Philippine Star. Archived from the original on April 19, 2022. Retrieved May 21, 2022. https://philstarlife.com/news-and-views/823718-angel-locsin-leyte-typhoon-agaton-evacuees
Parel, Fatima (March 22, 2009). "Angel Locsin: Angel in disguise". The Philippine Star. Archived from the original on May 3, 2022. Retrieved May 21, 2022. https://www.philstar.com/lifestyle/allure/2009/03/22/450301/angel-locsin-angel-disguise
Estella, Rose Anne (May 28, 2021). "Angel Locsin Is Real Super Hero". Mega. Archived from the original on May 28, 2021. Retrieved May 21, 2022. https://mega.onemega.com/angel-locsin-is-real-super-hero/
Plaza, Gerry (July 20, 2020). "Real-life 'Darna': Photos of Angel Locsin showing act of kindness over the years". ABS-CBN Entertainment. Archived from the original on January 24, 2021. Retrieved May 21, 2022. https://ent.abs-cbn.com/thegeneralsdaughter/articles-photos/real-life-darna-photos-angel-locsin-showing-act-of-kindness-over-the-years-14699
Cruz, Marinel (June 18, 2020). "Angel Locsin balks at 'real-life Darna' title: I have no hero complex". Philippine Daily Inquirer. Archived from the original on February 25, 2022. Retrieved May 21, 2022. https://entertainment.inquirer.net/379621/angel-locsin-balks-at-real-life-darna-title-i-have-no-hero-complex
"Angel Locsin channels Monroe in ad campaign". ABS-CBN Entertainment. September 27, 2012. Archived from the original on May 22, 2022. Retrieved May 21, 2022. https://news.abs-cbn.com/lifestyle/09/27/12/angel-locsin-channels-monroe-ad-campaign
Matalog, Patricia (March 17, 2020). "Angel Locsin's sexiest magazine covers through the years!". Star Cinema. Archived from the original on December 3, 2020. Retrieved May 21, 2022. https://starcinema.abs-cbn.com/2020/3/17/photos/angel-locsin-sexiest-magazine-covers-through-the-y-58708
"Angel Locsin is 2010 FHM sexiest woman". ABS-CBN Entertainment. June 29, 2010. Archived from the original on August 11, 2021. Retrieved May 20, 2022. https://news.abs-cbn.com/entertainment/06/29/10/angel-locsin-2010-fhm-sexiest-woman
Sources for accolades from Yes! magazine's annual beauty list:
In 2009: "One hundred stars featured in YES! Most Beautiful issue". Yes!. June 20, 2009. Archived from the original on July 10, 2022. Retrieved May 21, 2022.
In 2014: "60 Kapamilya stars in 'Most Beautiful' list". ABS-CBN Entertainment. July 30, 2014. Archived from the original on January 22, 2022. Retrieved May 21, 2022.
In 2016: "Alden Richards and Maine Mendoza lead this year's list of A-listers, box-office stars, love teams, and more". Yes!. July 13, 2016. Archived from the original on January 22, 2022. Retrieved May 21, 2022.
In 2018: Abellon, Bam (June 21, 2018). "YES! 100 Most Beautiful: New Generation A-Listers". Philippine Entertainment Portal. Archived from the original on January 22, 2022. Retrieved May 21, 2022.
/wiki/Yes!_(Philippine_magazine)
"Eastwood Walk of Fame gets new stars". ABS-CBN Entertainment. December 2, 2011. Archived from the original on January 25, 2020. Retrieved May 21, 2022. https://news.abs-cbn.com/entertainment/12/01/11/eastwood-walk-fame-gets-33-new-stars
Valle, Jocelyn (January 21, 2005). "Angel Locsin cried herself to sleep grieving at the memorial park". Philippine Daily Inquirer. Archived from the original on May 22, 2022. Retrieved May 21, 2022. https://books.google.com/books?id=P1g1AAAAIBAJ&dq=angel+locsin+miko+sotto&pg=PA32&article_id=1427,8665111
Lo, Ricky (February 17, 2004). "Angel: Life without Miko". The Philippine Star. Archived from the original on March 6, 2022. Retrieved May 21, 2022. https://www.philstar.com/entertainment/2004/02/17/239292/angel-life-without-miko
Lo, Ricky (October 15, 2006). "Oyo Sotto & Angel Locsin: Love Actually". The Philippine Star. Archived from the original on May 22, 2022. Retrieved May 21, 2022. https://www.philstar.com/entertainment/2006/10/15/363035/oyo-sotto-amp-angel-locsin-love-actually
Cruz, Marinel (April 20, 2005). "Angel dated Dennis". Philippine Daily Inquirer. Archived from the original on April 29, 2022. Retrieved April 29, 2022. https://books.google.com/books?id=BK41AAAAIBAJ&dq=angel+locsin+prepare+role+darna&pg=PA31&article_id=3572,2555318
"Angel Locsin confirms break-up with Phil". ABS-CBN Entertainment. October 25, 2013. Archived from the original on February 1, 2020. Retrieved May 21, 2022. https://news.abs-cbn.com/entertainment/10/24/13/angel-locsin-confirms-break-phil-report
"Angel Locsin denies breakup with Luis Manzano: 'We are fixing things'". Philippine Daily Inquirer. January 30, 2016. Archived from the original on September 28, 2020. Retrieved May 21, 2022. https://entertainment.inquirer.net/189066/angel-locsin-denies-breakup-with-luis-manzano-we-are-fixing-things
Grana, Rhia (August 9, 2021). "Meet Neil Arce, the man who got Angel Locsin to say 'I do'". ABS-CBN News Channel. Archived from the original on August 15, 2021. Retrieved May 21, 2022. https://news.abs-cbn.com/ancx/culture/spotlight/08/09/21/meet-neil-arce-the-man-who-got-angel-locsin-to-say-i-do
Matalog, Patricia (July 1, 2019). "The complete timeline of Angel Locsin and Neil Arce's relationship". Star Cinema. Archived from the original on January 16, 2021. Retrieved May 21, 2022. https://starcinema.abs-cbn.com/2019/7/1/photos/the-complete-timeline-of-angel-locsin-and-neil-arc-50509
Matalog, Patricia (July 1, 2019). "The complete timeline of Angel Locsin and Neil Arce's relationship". Star Cinema. Archived from the original on January 16, 2021. Retrieved May 21, 2022. https://starcinema.abs-cbn.com/2019/7/1/photos/the-complete-timeline-of-angel-locsin-and-neil-arc-50509
Basco, Karl Cedrick (August 14, 2021). "From casual outfits to kikiam, fishball in reception: Angel, Neil share story behind simple wedding". ABS-CBN Entertainment. Archived from the original on August 22, 2021. Retrieved May 21, 2022. https://news.abs-cbn.com/entertainment/08/14/21/angel-neil-share-story-behind-simple-wedding-ceremony
Pasajol, Anne (March 31, 2022). "Angel Locsin no plans on having baby yet due to thyroid problem". INQUIRER.net. Retrieved January 1, 2025. https://entertainment.inquirer.net/443472/angel-locsin-no-plans-on-having-baby-yet-due-to-thyroid-problem
"Angel Locsin Movie Box Office Results". Box Office Mojo. Archived from the original on May 22, 2022. Retrieved May 21, 2022. https://www.boxofficemojo.com/name/nm1246742/
Abanilla, Clarizel (July 31, 2017). "Angel Locsin wins Best Supporting Actress at 57th Asia-Pacific Film Festival". Philippine Daily Inquirer. Archived from the original on May 8, 2022. Retrieved May 8, 2022. https://entertainment.inquirer.net/236791/angel-locsin-wins-best-supporting-actress-57th-asia-pacific-film-festival
Calderon, Nora (April 11, 2013). "Vice Ganda, Kris Aquino, and Ai-Ai delas Alas named Phenomenal Box-Office Stars at 44th Box-Office Entertainment Awards" (in Tagalog). Philippine Entertainment Portal. Archived from the original on August 11, 2021. Retrieved May 21, 2022. https://www.pep.ph/news/local/38215/vice-ganda-kris-aquino-and-ai-ai-delas-alas-named-phenomenal-box-office-stars-at-44th-box-office-ent
"Angel, 'El Presidente' win at FAMAS Awards". ABS-CBN Entertainment. April 22, 2013. Archived from the original on May 7, 2022. Retrieved May 7, 2022. https://news.abs-cbn.com/entertainment/04/22/13/angel-el-presidente-win-famas-awards
Dimaculangan, Jocelyn (June 2, 2013). "Angel Locsin and John Lloyd Cruz win top acting awards in 31st Luna Awards". Philippine Entertainment Portal. Archived from the original on August 11, 2021. Retrieved May 21, 2022. https://www.pep.ph/news/local/38916/angel-locsin-and-john-lloyd-cruz-win-top-acting-awards-in-31st-luna-awards
"'El Presidente,' Angel Locsin win at Star Awards". ABS-CBN Entertainment. March 11, 2013. Archived from the original on May 7, 2022. Retrieved May 7, 2022. https://news.abs-cbn.com/entertainment/03/11/13/el-presidente-angel-locsin-win-star-awards
"Kapamilya stars, wagi sa 43rd Box-Office Entertainment Awards" [Kapamilya stars, win big at the 43rd Box-Office Entertainment Awards] (in Tagalog). ABS-CBN Entertainment. April 17, 2012. Archived from the original on November 26, 2013. Retrieved May 7, 2022. https://web.archive.org/web/20131126071439/http://dzmm.abs-cbnnews.com/news/Entertainment/Kapamilya_stars,_wagi_sa_43rd_Box-Office_Entertainment_Awards_.html
"In the Name of Love wins big at PMPC Star Awards". ABS-CBN Entertainment. March 15, 2012. Archived from the original on May 7, 2022. Retrieved May 7, 2022. https://news.abs-cbn.com/entertainment/03/14/12/name-love-wins-big-pmpc-star-awards
"ABS-CBN shows, stars win big at the 33rd Star Awards for TV". ABS-CBN Entertainment. October 14, 2019. Archived from the original on January 25, 2020. Retrieved May 19, 2022. https://news.abs-cbn.com/entertainment/10/14/19/abs-cbn-shows-stars-win-big-at-the-33rd-star-awards-for-tv
"ABS-CBN shines in 51st Box Office Entertainment Awards". ABS-CBN Entertainment. October 23, 2020. Archived from the original on May 19, 2022. Retrieved May 19, 2022. https://www.abs-cbn.com/newsroom/news-releases/2020/10/23/abscbn-awards-guillermo?lang=en