Menu
Home
People
Places
Arts
History
Plants & Animals
Science
Life & Culture
Technology
Reference.org
Bisphenol AF
open-in-new
<h2 id="biological-and-chemical-action">Biological and Chemical Action</h2> <p class="note">Further information: <a href="/facts/Endocrine_disruptor/Yk2hfnTj">endocrine disruptor</a></p> <p>Bisphenol AF is an endocrine disrupting chemical.<a class="footnote-ref" id="fnref:1" href="#fn:1"><sup>1</sup></a> Whereas BPA binds with human <a href="/facts/Estrogen-related_receptor_gamma/NjN0UUsw">estrogen-related receptor gamma</a> (ERR-γ), BPAF all but ignores ERR-γ. Instead, BPAF activates <a href="/facts/Estrogen-related_receptor_alpha/IAP9T85A">ERR-α</a> and binds to and disables <a href="/facts/Estrogen-related_receptor_beta/hAIquxLm">ERR-β</a>.<a class="footnote-ref" id="fnref:2" href="#fn:2"><sup>2</sup></a> </p><p>The chemical shifts in <a href="/facts/Proton_nuclear_magnetic_resonance/g9AGxvSP">1H</a>, <a href="/facts/Carbon-13_nuclear_magnetic_resonance/0RlV1ajq">13C</a> and 19F <a href="/facts/NMR_spectroscopy/SFKgdthI">NMR spectroscopy</a> are given in the literature.<a class="footnote-ref" id="fnref:3" href="#fn:3"><sup>3</sup></a> </p> <h2 id="applications">Applications</h2> <p>Bisphenol AF is used as a crosslinking agent for certain <a href="/facts/Fluoroelastomers/5PNRV20t">fluoroelastomers</a> and as a monomer for polyimides, polyamides, polyesters, polycarbonate copolymers and other specialty polymers. Polymers containing Bisphenol AF are useful in specialties such as high-temperature composites and electronic materials. Industries include cosmetics, chemical manufacturing, production of metals and rubber. It can also be a plastic additive.<a class="footnote-ref" id="fnref:4" href="#fn:4"><sup>4</sup></a> </p> <h2 id="see-also">See also</h2> <ul><li><a href="/facts/Bisphenol_A/8AAPhAh0">Bisphenol A</a></li> <li><a href="/facts/Bisphenol_S/r2n2MphA">Bisphenol S</a></li></ul> <h2 id="references">References</h2> <ol> <li id="fn:1"><p>Escrivá, Laura; Hanberg, Annika; Zilliacus, Johanna; Beronius, Anna (September 2019). "Assessment of the endocrine disrupting properties of Bisphenol AF according to the EU criteria and ECHA/EFSA guidance". EFSA Journal. 17 (EU‐FORA: Series 2): e170914. doi:10.2903/j.efsa.2019.e170914. PMC 7015508. PMID 32626472. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015508" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015508</a> <a href="#fnref:1" class="footnote-back-ref">↩</a></p></li> <li id="fn:2"><p>"Janet Raloff: Another plastics ingredient raises safety concerns, Science News, June 5th, 2010; Vol.177 #12 (p. 14)". Archived from the original on 2012-09-27. Retrieved 2010-06-11. <a href="https://web.archive.org/web/20120927005453/http://www.sciencenews.org/view/generic/id/59113" target="_blank">https://web.archive.org/web/20120927005453/http://www.sciencenews.org/view/generic/id/59113</a> <a href="#fnref:2" class="footnote-back-ref">↩</a></p></li> <li id="fn:3"><p>Hayasaka, Tatsuya; Katsuhara, Yutaka; Kume, Takashi; Yamazaki, Takashi (2011). "HF-mediated equilibrium between fluorinated ketones and the corresponding α-fluoroalcohols". Tetrahedron. 67 (12): 2215–2219. doi:10.1016/j.tet.2011.01.087. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:3" class="footnote-back-ref">↩</a></p></li> <li id="fn:4"><p>"Bisphenol AF". PubChem. National Library of Medicine. Retrieved 20 January 2021. <a href="https://pubchem.ncbi.nlm.nih.gov/compound/Bisphenol-AF" target="_blank">https://pubchem.ncbi.nlm.nih.gov/compound/Bisphenol-AF</a> <a href="#fnref:4" class="footnote-back-ref">↩</a></p></li> </ol>