It has become widely used in the testing of patients with multiple sclerosis as patients with this disease frequently have an impaired performance on this test. The PASAT was included in the Multiple Sclerosis Functional Composite 3 as a cognitive measure. However, the use of the PASAT in clinical trials in MS it has shown to be problematic as there are significant practice effects over repeated measures; typically the effect of treatment is reflected by a larger improvement on the test compared to the control group.
Spreen O., Strauss E.: A Compendium of Neuropsychological Tests; ²1998; New York, Oxford University press ↩
Gronwall DM. Paced auditory serial-addition task: a measure of recovery from concussion. Perceptual and Motor Skills. 1977 Apr;44(2):367–373 ↩
Fischer S. et al. (2001) Multiple Sclerosis Functional Composite, New York; The National Multiple Sclerosis Society http://pasat.us/PDF/MSFC_Manual.pdf seen Oct 26, 2010 http://pasat.us/PDF/MSFC_Manual.pdf ↩