Tinctures are often made of a combination of ethyl alcohol and water as solvents, each dissolving constituents the other is unable to, or weaker at. Varying their proportions can also produce different levels of constituents in the final extraction. As an antimicrobial, alcohol also acts as a preservative.
A downside of using alcohol as a solvent is that ethanol has a tendency to denature some organic compounds, reducing or destroying their effectiveness. This tendency can also have undesirable effects when extracting botanical constituents, such as polysaccharides. Certain other constituents, common among them proteins, can become irreversibly denatured, or "pickled" by the alcohol. Alcohol can also have damaging effects on some aromatic compounds.
Ether and propylene glycol based tinctures are not suitable for internal consumption, although they are used in preparations for external use, such as personal care creams and ointments.
Some examples that were formerly common in medicine4 include:
Examples of spirits include:
Groot Handboek Geneeskrachtige Planten by Geert Verhelst ↩
Ullian, Naomi (2016-09-19). "How To Make A Medicinal Mushroom Double-Extraction Tincture". Herbal Academy. Retrieved 2021-01-12. https://theherbalacademy.com/make-medicinal-mushroom-double-extraction-tincture/ ↩
The Pharmacopoeia of the United States, 1850 ed. ↩