The database uses a "tiered approach — comprising multiple, redundant tiers of transaction engines (TE) and storage managers (SM)." This approach helps scale the data predictably in the cloud. NuoDB domains consist of several redundant TEs and SMs that can run on the same platform. Adding database capacity can be done by adding more TEs or SMs. The NuoDB 2.6 release added support for active-active database deployments across multiple Amazon Web Services (AWS) availability zones. Unlike other database systems, NuoDB makes it possible to expand its databases by adding more servers rather than simply replacing hardware.
The system was designed to align with – and expand upon – IBM computer scientist Edgar F. Codd's 12 rules for relational databases. It adds the ability to run anywhere; elastic scalability; nonstop availability; a single, logical database; and distributed security. It is available in a free developer version ("Community Edition") and an enterprise version. The Community Edition was expanded on January 31, 2017 to enable scale-out across multiple hosts.
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