Kringle domain

<h2 id="human-proteins-containing-this-domain">Human proteins containing this domain</h2>
<p><a href="/facts/Activating_transcription_factor_2/kvue3G39">ATF</a>; <a href="/facts/Factor_XII/kH2139lU">F12</a>; <a href="/facts/Thrombin/sU9x3MeH">F2</a>; <a href="/facts/HABP2/wgfJNkQF">HABP2</a>; <a href="/facts/Hepatocyte_growth_factor/7WLEIPn4">HGF</a>; <a href="/facts/HGFAC/sgEQ57gm">HGFAC</a>; <a href="/facts/KREMEN1/ADpk5pzT">KREMEN1</a>; KREMEN2;
<a href="/facts/Lipoprotein(a)/fFJ84589">LPA</a>; LPAL2; <a href="/facts/MST1/cv7IySj7">MST1</a>; <a href="/facts/PIK3IP1/G2nPAoxp">PIK3IP1</a>; <a href="/facts/Tissue_plasminogen_activator/CQ94BqkJ">PLAT</a>; <a href="/facts/PLAU/KLw2T4lV">PLAU</a>; <a href="/facts/Plasminogen/bfLCyyPt">PLG</a>; PRSS12; <a href="/facts/ROR1/j9nVdEC7">ROR1</a>; <a href="/facts/ROR2/vBsm1Esr">ROR2</a>;
</p>

<h2 id="external-links">External links</h2>
<ul><li><a href="http://www.expasy.org/cgi-bin/nicedoc.pl?PDOC00020">Kringle domain</a> <a href="https://web.archive.org/web/20200528132412/https://web.expasy.org/cgi-bin/unavailable.cgi?type=redirect&query=nicedoc.pl">Archived</a> 28 May 2020 at the <a href="/facts/Wayback_Machine/nmQ3a6JC">Wayback Machine</a> in <a href="/facts/PROSITE/TcqJLVBc">PROSITE</a></li>
<li><a href="http://smart.embl-heidelberg.de/smart/do_annotation.pl?DOMAIN=KR">KR domain entry in the SMART database</a></li>
<li><a href="http://sbi.imim.es/web/files/projects/master/2010/Coagulation_serine_proteases/Prothrombin.html">Kringle domain cartoon, under Prothrombin Structure</a></li></ul>

<h2 id="references">References</h2>

<ol>
<li id="fn:1"><p>Fujikawa K, McMullen BA (1985). "Amino acid sequence of the heavy chain of human alpha-factor XIIa (activated Hageman factor)". J. Biol. Chem. 260 (9): 5328–5341. doi:10.1016/S0021-9258(18)89026-3. PMID 3886654. <a href="https://doi.org/10.1016%2FS0021-9258%2818%2989026-3" target="_blank">https://doi.org/10.1016%2FS0021-9258%2818%2989026-3</a> <a href="#fnref:1" class="footnote-back-ref">↩</a></p></li>
<li id="fn:2"><p>Patthy L, Trexler M, Banyai L, Varadi A, Vali Z (1984). "Kringles: modules specialized for protein binding. Homology of the gelatin-binding region of fibronectin with the kringle structures of proteases". FEBS Lett. 171 (1): 131–136. doi:10.1016/0014-5793(84)80473-1. PMID 6373375. S2CID 12669742. <a href="https://doi.org/10.1016%2F0014-5793%2884%2980473-1" target="_blank">https://doi.org/10.1016%2F0014-5793%2884%2980473-1</a> <a href="#fnref:2" class="footnote-back-ref">↩</a></p></li>
<li id="fn:3"><p>Atkinson RA, Williams RJ (1990). "Solution structure of the kringle 4 domain from human plasminogen by 1H nuclear magnetic resonance spectroscopy and distance geometry". J. Mol. Biol. 212 (3): 541–552. doi:10.1016/0022-2836(90)90330-O. PMID 2157850. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:3" class="footnote-back-ref">↩</a></p></li>
<li id="fn:4"><p>Castellino FJ, Beals JM (1987). "The genetic relationships between the kringle domains of human plasminogen, prothrombin, tissue plasminogen activator, urokinase, and coagulation factor XII". J. Mol. Evol. 26 (4): 358–369. Bibcode:1987JMolE..26..358C. doi:10.1007/BF02101155. PMID 3131537. S2CID 22249781. <a href="/wiki/Bibcode_(identifier)" target="_blank">/wiki/Bibcode_(identifier)</a> <a href="#fnref:4" class="footnote-back-ref">↩</a></p></li>
<li id="fn:5"><p>Patthy L (1985). "Evolution of the proteases of blood coagulation and fibrinolysis by assembly from modules". Cell. 41 (3): 657–663. doi:10.1016/S0092-8674(85)80046-5. PMID 3891096. S2CID 32104232. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:5" class="footnote-back-ref">↩</a></p></li>
<li id="fn:6"><p>Takahashi K, Ikeo K, Gojobori T (1991). "Evolutionary origin of numerous kringles in human and simian apolipoprotein(a)". FEBS Lett. 287 (1): 146–148. doi:10.1016/0014-5793(91)80036-3. PMID 1879523. S2CID 13366195. <a href="https://doi.org/10.1016%2F0014-5793%2891%2980036-3" target="_blank">https://doi.org/10.1016%2F0014-5793%2891%2980036-3</a> <a href="#fnref:6" class="footnote-back-ref">↩</a></p></li>
</ol>

Kringle domain open-in-new

Kringle domain