Pirimiphos methyl is manufactured in a two-step process in which N,N-diethylguanidine is reacted with ethyl acetoacetate to form a pyrimidine ring and its hydroxy group is combined with dimethyl chlorothiophosphate to form the insecticide.8
Pyrimiphos-ethyl is a related insecticide in which the methoxy groups are replaced with ethoxy groups.
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