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Plaque reduction neutralization test
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<h2 id="see-also">See also</h2> <ul><li><a href="/facts/ELISA/8yvpYDtH">ELISA</a> – Method to detect an antigen using an antibody and enzyme</li> <li><a href="/facts/Immune_complex/s4kKT3lc">Immune complex</a> – Molecule formed binding antigens to antibodies</li> <li><a href="/facts/Virus_quantification/lyyPqroe">Viral quantification using the plaque assay</a></li></ul> <h2 id="references">References</h2> <ol> <li id="fn:1"><p>Schmidt, N J; Dennis, J; Lennette, E H (July 1976). "Plaque reduction neutralization test for human cytomegalovirus based upon enhanced uptake of neutral red by virus-infected cells". Journal of Clinical Microbiology. 4 (1): 61–66. doi:10.1128/jcm.4.1.61-66.1976. ISSN 0095-1137. PMC 274391. PMID 182716. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC274391" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC274391</a> <a href="#fnref:1" class="footnote-back-ref">↩</a></p></li> <li id="fn:2"><p>Klasse, P. J. (2014-09-09). "Neutralization of Virus Infectivity by Antibodies: Old Problems in New Perspectives". Advances in Biology. 2014: 1–24. doi:10.1155/2014/157895. PMC 4835181. PMID 27099867. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835181" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835181</a> <a href="#fnref:2" class="footnote-back-ref">↩</a></p></li> <li id="fn:3"><p>Schmidt, N J; J Dennis; E H Lennette (July 1976). "Plaque reduction neutralization test for human cytomegalovirus based upon enhanced uptake of neutral red by virus-infected cells" (PDF). Journal of Clinical Microbiology. 4 (1): 61–66. doi:10.1128/jcm.4.1.61-66.1976. ISSN 0095-1137. PMC 274391. PMID 182716. <a href="http://jcm.asm.org/cgi/reprint/4/1/61.pdf" target="_blank">http://jcm.asm.org/cgi/reprint/4/1/61.pdf</a> <a href="#fnref:3" class="footnote-back-ref">↩</a></p></li> <li id="fn:4"><p>Thomas, Stephen J.; Ananda Nisalak; Kathryn B. Anderson; Daniel H. Libraty; Siripen Kalayanarooj; David W. Vaughn; Robert Putnak; Robert V. Gibbons; Richard Jarman; Timothy P. Endy (November 2009). "Dengue Plaque Reduction Neutralization Test (PRNT) in Primary and Secondary Dengue Virus Infections: How Alterations in Assay Conditions Impact Performance". The American Journal of Tropical Medicine and Hygiene. 81 (5): 825–833. doi:10.4269/ajtmh.2009.08-0625. ISSN 0002-9637. PMC 2835862. PMID 19861618. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835862" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835862</a> <a href="#fnref:4" class="footnote-back-ref">↩</a></p></li> <li id="fn:5"><p>Ratnam, S; V Gadag; R West; J Burris; E Oates; F Stead; N Bouilianne (1995-04-01). "Comparison of commercial enzyme immunoassay kits with plaque reduction neutralization test for detection of measles virus antibody". J. Clin. Microbiol. 33 (4): 811–815. doi:10.1128/JCM.33.4.811-815.1995. PMC 228046. PMID 7790442. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC228046" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC228046</a> <a href="#fnref:5" class="footnote-back-ref">↩</a></p></li> <li id="fn:6"><p>Mukherjee, S.; Dowd, K. A.; Manhart, C. J.; Ledgerwood, J. E.; Durbin, A. P.; Whitehead, S. S.; Pierson, T. C. (2014). "Mechanism and Significance of Cell Type-Dependent Neutralization of Flaviviruses". Journal of Virology. 88 (13): 7210–7220. doi:10.1128/JVI.03690-13. ISSN 0022-538X. PMC 4054442. PMID 24741083. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054442" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054442</a> <a href="#fnref:6" class="footnote-back-ref">↩</a></p></li> </ol>