Menu
Home
People
Places
Arts
History
Plants & Animals
Science
Life & Culture
Technology
Reference.org
RYBP
open-in-new
<h2 id="interactions">Interactions</h2> <p>RYBP has been shown to <a href="/facts/Protein-protein_interaction/etvm9Wmg">interact</a> with: </p> <ul><li><a href="/facts/Abl_gene/h9pJd4jf">Abl gene</a>,<a class="footnote-ref" id="fnref:3" href="#fn:3"><sup>3</sup></a></li> <li><a href="/facts/CBX2_(gene)/SCqcaWPN"> CBX2</a>,<a class="footnote-ref" id="fnref:4" href="#fn:4"><sup>4</sup></a></li> <li><a href="/facts/Caspase_10/U9MKqQd3">Caspase 10</a>,<a class="footnote-ref" id="fnref:5" href="#fn:5"><sup>5</sup></a></li> <li><a href="/facts/E2F2/7FL75opB">E2F2</a>,<a class="footnote-ref" id="fnref:6" href="#fn:6"><sup>6</sup></a></li> <li><a href="/facts/E2F3/CCyp2Pog">E2F3</a>,<a class="footnote-ref" id="fnref:7" href="#fn:7"><sup>7</sup></a></li> <li><a href="/facts/Mdm2/9YmWxSF0">Mdm2</a>,<a class="footnote-ref" id="fnref:8" href="#fn:8"><sup>8</sup></a></li> <li><a href="/facts/RING1/6USechGc">RING1</a>,<a class="footnote-ref" id="fnref:9" href="#fn:9"><sup>9</sup></a><a class="footnote-ref" id="fnref:10" href="#fn:10"><sup>10</sup></a> and</li> <li><a href="/facts/YY1/Ec4E5UXR">YY1</a>.<a class="footnote-ref" id="fnref:11" href="#fn:11"><sup>11</sup></a></li></ul> <h2 id="further-reading">Further reading</h2> <ul><li>Zhu J, Shore SK (Dec 1996). <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC231708">"c-ABL tyrosine kinase activity is regulated by association with a novel SH3-domain-binding protein"</a>. <i>Molecular and Cellular Biology</i>. 16 (12): 7054–62. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1128%2Fmcb.16.12.7054">10.1128/mcb.16.12.7054</a>. <a href="/facts/PMC_(identifier)/dX1zMt71">PMC</a> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC231708">231708</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/8943360">8943360</a>.</li> <li>Trimarchi JM, Fairchild B, Wen J, Lees JA (Feb 2001). <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC29289">"The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex"</a>. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. 98 (4): 1519–24. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1073%2Fpnas.041597698">10.1073/pnas.041597698</a>. <a href="/facts/PMC_(identifier)/dX1zMt71">PMC</a> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC29289">29289</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/11171983">11171983</a>.</li> <li>Zheng L, Schickling O, Peter ME, Lenardo MJ (Aug 2001). <a href="https://doi.org/10.1074%2Fjbc.M102799200">"The death effector domain-associated factor plays distinct regulatory roles in the nucleus and cytoplasm"</a>. <i>The Journal of Biological Chemistry</i>. 276 (34): 31945–52. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1074%2Fjbc.M102799200">10.1074/jbc.M102799200</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/11395500">11395500</a>.</li> <li>Sawa C, Yoshikawa T, Matsuda-Suzuki F, Deléhouzée S, Goto M, Watanabe H, Sawada J, Kataoka K, Handa H (Jun 2002). <a href="https://doi.org/10.1074%2Fjbc.M203060200">"YEAF1/RYBP and YAF-2 are functionally distinct members of a cofactor family for the YY1 and E4TF1/hGABP transcription factors"</a>. <i>The Journal of Biological Chemistry</i>. 277 (25): 22484–90. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1074%2Fjbc.M203060200">10.1074/jbc.M203060200</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/11953439">11953439</a>.</li> <li>Schlisio S, Halperin T, Vidal M, Nevins JR (Nov 2002). <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC131074">"Interaction of YY1 with E2Fs, mediated by RYBP, provides a mechanism for specificity of E2F function"</a>. <i>The EMBO Journal</i>. 21 (21): 5775–86. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1093%2Femboj%2Fcdf577">10.1093/emboj/cdf577</a>. <a href="/facts/PMC_(identifier)/dX1zMt71">PMC</a> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC131074">131074</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/12411495">12411495</a>.</li> <li>Guelen L, Paterson H, Gäken J, Meyers M, Farzaneh F, Tavassoli M (Feb 2004). <a href="https://doi.org/10.1038%2Fsj.onc.1207224">"TAT-apoptin is efficiently delivered and induces apoptosis in cancer cells"</a>. <i>Oncogene</i>. 23 (5): 1153–65. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1038%2Fsj.onc.1207224">10.1038/sj.onc.1207224</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/14691460">14691460</a>.</li> <li>Danen-van Oorschot AA, Voskamp P, Seelen MC, van Miltenburg MH, Bolk MW, Tait SW, Boesen-de Cock JG, Rohn JL, Borst J, Noteborn MH (May 2004). <a href="https://doi.org/10.1038%2Fsj.cdd.4401391">"Human death effector domain-associated factor interacts with the viral apoptosis agonist Apoptin and exerts tumor-preferential cell killing"</a>. <i>Cell Death and Differentiation</i>. 11 (5): 564–73. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1038%2Fsj.cdd.4401391">10.1038/sj.cdd.4401391</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/14765135">14765135</a>.</li> <li>Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". <i>Nature</i>. 437 (7062): 1173–8. <a href="/facts/Bibcode_(identifier)/9HtdQSGB">Bibcode</a>:<a href="https://ui.adsabs.harvard.edu/abs/2005Natur.437.1173R">2005Natur.437.1173R</a>. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1038%2Fnature04209">10.1038/nature04209</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/16189514">16189514</a>. <a href="/facts/S2CID_(identifier)/ldJsHa2Y">S2CID</a> <a href="https://api.semanticscholar.org/CorpusID:4427026">4427026</a>.</li></ul> <h2 id="references">References</h2> <ol> <li id="fn:1"><p>García E, Marcos-Gutiérrez C, del Mar Lorente M, Moreno JC, Vidal M (Jun 1999). "RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex, and with the transcription factor YY1". The EMBO Journal. 18 (12): 3404–18. doi:10.1093/emboj/18.12.3404. PMC 1171420. PMID 10369680. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1171420" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1171420</a> <a href="#fnref:1" class="footnote-back-ref">↩</a></p></li> <li id="fn:2"><p>"Entrez Gene: RYBP RING1 and YY1 binding protein". <a href="https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23429" target="_blank">https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23429</a> <a href="#fnref:2" class="footnote-back-ref">↩</a></p></li> <li id="fn:3"><p>Zhu J, Shore SK (Dec 1996). "c-ABL tyrosine kinase activity is regulated by association with a novel SH3-domain-binding protein". Molecular and Cellular Biology. 16 (12): 7054–62. doi:10.1128/mcb.16.12.7054. PMC 231708. PMID 8943360. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC231708" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC231708</a> <a href="#fnref:3" class="footnote-back-ref">↩</a></p></li> <li id="fn:4"><p>García E, Marcos-Gutiérrez C, del Mar Lorente M, Moreno JC, Vidal M (Jun 1999). "RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex, and with the transcription factor YY1". The EMBO Journal. 18 (12): 3404–18. doi:10.1093/emboj/18.12.3404. PMC 1171420. PMID 10369680. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1171420" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1171420</a> <a href="#fnref:4" class="footnote-back-ref">↩</a></p></li> <li id="fn:5"><p>Zheng L, Schickling O, Peter ME, Lenardo MJ (Aug 2001). "The death effector domain-associated factor plays distinct regulatory roles in the nucleus and cytoplasm". The Journal of Biological Chemistry. 276 (34): 31945–52. doi:10.1074/jbc.M102799200. PMID 11395500. <a href="https://doi.org/10.1074%2Fjbc.M102799200" target="_blank">https://doi.org/10.1074%2Fjbc.M102799200</a> <a href="#fnref:5" class="footnote-back-ref">↩</a></p></li> <li id="fn:6"><p>Schlisio S, Halperin T, Vidal M, Nevins JR (Nov 2002). "Interaction of YY1 with E2Fs, mediated by RYBP, provides a mechanism for specificity of E2F function". The EMBO Journal. 21 (21): 5775–86. doi:10.1093/emboj/cdf577. PMC 131074. PMID 12411495. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC131074" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC131074</a> <a href="#fnref:6" class="footnote-back-ref">↩</a></p></li> <li id="fn:7"><p>Schlisio S, Halperin T, Vidal M, Nevins JR (Nov 2002). "Interaction of YY1 with E2Fs, mediated by RYBP, provides a mechanism for specificity of E2F function". The EMBO Journal. 21 (21): 5775–86. doi:10.1093/emboj/cdf577. PMC 131074. PMID 12411495. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC131074" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC131074</a> <a href="#fnref:7" class="footnote-back-ref">↩</a></p></li> <li id="fn:8"><p>Chen D, Zhang J, Li M, Rayburn ER, Wang H, Zhang R (Feb 2009). "RYBP stabilizes p53 by modulating MDM2". EMBO Reports. 10 (2): 166–72. doi:10.1038/embor.2008.231. PMC 2637313. PMID 19098711. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637313" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637313</a> <a href="#fnref:8" class="footnote-back-ref">↩</a></p></li> <li id="fn:9"><p>García E, Marcos-Gutiérrez C, del Mar Lorente M, Moreno JC, Vidal M (Jun 1999). "RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex, and with the transcription factor YY1". The EMBO Journal. 18 (12): 3404–18. doi:10.1093/emboj/18.12.3404. PMC 1171420. PMID 10369680. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1171420" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1171420</a> <a href="#fnref:9" class="footnote-back-ref">↩</a></p></li> <li id="fn:10"><p>Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026. <a href="/wiki/Huda_Zoghbi" target="_blank">/wiki/Huda_Zoghbi</a> <a href="#fnref:10" class="footnote-back-ref">↩</a></p></li> <li id="fn:11"><p>García E, Marcos-Gutiérrez C, del Mar Lorente M, Moreno JC, Vidal M (Jun 1999). "RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex, and with the transcription factor YY1". The EMBO Journal. 18 (12): 3404–18. doi:10.1093/emboj/18.12.3404. PMC 1171420. PMID 10369680. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1171420" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1171420</a> <a href="#fnref:11" class="footnote-back-ref">↩</a></p></li> </ol>