Menu
Home
People
Places
Arts
History
Plants & Animals
Science
Life & Culture
Technology
Reference.org
Tipepidine
open-in-new
<h2 id="see-also">See also</h2> <ul><li><a href="/facts/Cough_syrup/2Qe0AjMx">Cough syrup</a></li> <li><a href="/facts/Noscapine/lK1dEsPG">Noscapine</a></li> <li><a href="/facts/Codeine/lr7WHXmX">Codeine</a>; <a href="/facts/Pholcodine/nkAYktJm">Pholcodine</a></li> <li><a href="/facts/Dextromethorphan/Jq9UgD4M">Dextromethorphan</a>; <a href="/facts/Dimemorfan/rCPzh2zy">Dimemorfan</a></li> <li><a href="/facts/Racemorphan/LN9r8Mku">Racemorphan</a>; <a href="/facts/Dextrorphan/9M93zQRe">Dextrorphan</a>; <a href="/facts/Levorphanol/PRz3R6G6">Levorphanol</a></li> <li><a href="/facts/Butamirate/EWHzQJtu">Butamirate</a></li> <li><a href="/facts/Pentoxyverine/KUeXtpoR">Pentoxyverine</a></li> <li><a href="/facts/Cloperastine/cYKKk2lj">Cloperastine</a>; Levocloperastine</li> <li><a href="/facts/Guaifenesin/6M5ShWzC">Guaifenesin</a></li> <li><a href="/facts/Timepidium_bromide/fof0mNrK">Timepidium bromide</a></li></ul> <h2 id="references">References</h2> <ol> <li id="fn:1"><p>Ganellin CR, Triggle DJ (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. pp. 1988–. ISBN 978-0-412-46630-4. <a href="978-0-412-46630-4" target="_blank">978-0-412-46630-4</a> <a href="#fnref:1" class="footnote-back-ref">↩</a></p></li> <li id="fn:2"><p>Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 1649–. ISBN 978-3-88763-075-1. <a href="978-3-88763-075-1" target="_blank">978-3-88763-075-1</a> <a href="#fnref:2" class="footnote-back-ref">↩</a></p></li> <li id="fn:3"><p>Kawaura K, Ogata Y, Inoue M, Honda S, Soeda F, Shirasaki T, Takahama K (December 2009). "The centrally acting non-narcotic antitussive tipepidine produces antidepressant-like effect in the forced swimming test in rats". Behavioural Brain Research. 205 (1): 315–318. doi:10.1016/j.bbr.2009.07.004. PMID 19616036. S2CID 29236491. <a href="https://kumadai.repo.nii.ac.jp/?action=repository_action_common_download&item_id=24712&item_no=1&attribute_id=21&file_no=1" target="_blank">https://kumadai.repo.nii.ac.jp/?action=repository_action_common_download&item_id=24712&item_no=1&attribute_id=21&file_no=1</a> <a href="#fnref:3" class="footnote-back-ref">↩</a></p></li> <li id="fn:4"><p>ES 272195, "Procedure for the preparation of a new piperidine derivative of anti-nutritional activity", published 1 March 1962, assigned to Antonio Gallardo SA. <a href="https://worldwide.espacenet.com/textdoc?DB=EPODOC&IDX=ES272195" target="_blank">https://worldwide.espacenet.com/textdoc?DB=EPODOC&IDX=ES272195</a> <a href="#fnref:4" class="footnote-back-ref">↩</a></p></li> <li id="fn:5"><p>Imai Y, Ishii W, Endo A, Arakawa C, Kohira R, Fujita Y, et al. (October 2011). "Tipepidine hibenzate intoxication". Pediatrics International. 53 (5): 779–781. doi:10.1111/j.1442-200X.2010.03297.x. PMID 21955016. S2CID 205484528. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:5" class="footnote-back-ref">↩</a></p></li> <li id="fn:6"><p>Ganellin CR, Triggle DJ (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. pp. 1988–. ISBN 978-0-412-46630-4. <a href="978-0-412-46630-4" target="_blank">978-0-412-46630-4</a> <a href="#fnref:6" class="footnote-back-ref">↩</a></p></li> <li id="fn:7"><p>Imai Y, Ishii W, Endo A, Arakawa C, Kohira R, Fujita Y, et al. (October 2011). "Tipepidine hibenzate intoxication". Pediatrics International. 53 (5): 779–781. doi:10.1111/j.1442-200X.2010.03297.x. PMID 21955016. S2CID 205484528. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:7" class="footnote-back-ref">↩</a></p></li> <li id="fn:8"><p>Imai Y, Ishii W, Endo A, Arakawa C, Kohira R, Fujita Y, et al. (October 2011). "Tipepidine hibenzate intoxication". Pediatrics International. 53 (5): 779–781. doi:10.1111/j.1442-200X.2010.03297.x. PMID 21955016. S2CID 205484528. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:8" class="footnote-back-ref">↩</a></p></li> <li id="fn:9"><p>Kawaura K, Ogata Y, Inoue M, Honda S, Soeda F, Shirasaki T, Takahama K (December 2009). "The centrally acting non-narcotic antitussive tipepidine produces antidepressant-like effect in the forced swimming test in rats". Behavioural Brain Research. 205 (1): 315–318. doi:10.1016/j.bbr.2009.07.004. PMID 19616036. S2CID 29236491. <a href="https://kumadai.repo.nii.ac.jp/?action=repository_action_common_download&item_id=24712&item_no=1&attribute_id=21&file_no=1" target="_blank">https://kumadai.repo.nii.ac.jp/?action=repository_action_common_download&item_id=24712&item_no=1&attribute_id=21&file_no=1</a> <a href="#fnref:9" class="footnote-back-ref">↩</a></p></li> <li id="fn:10"><p>Kawaura K, Honda S, Soeda F, Shirasaki T, Takahama K (May 2010). "[Novel antidepressant-like action of drugs possessing GIRK channel blocking action in rats]". Yakugaku Zasshi. 130 (5): 699–705. doi:10.1248/yakushi.130.699. PMID 20460867. <a href="https://doi.org/10.1248%2Fyakushi.130.699" target="_blank">https://doi.org/10.1248%2Fyakushi.130.699</a> <a href="#fnref:10" class="footnote-back-ref">↩</a></p></li> <li id="fn:11"><p>Sasaki T, Hashimoto K, Tachibana M, Kurata T, Kimura H, Komatsu H, et al. (2014). "Tipepidine in adolescent patients with depression: a 4 week, open-label, preliminary study". Neuropsychiatric Disease and Treatment. 10: 719–722. doi:10.2147/NDT.S63075. PMC 4015794. PMID 24833905. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015794" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015794</a> <a href="#fnref:11" class="footnote-back-ref">↩</a></p></li> <li id="fn:12"><p>Honda S, Kawaura K, Soeda F, Shirasaki T, Takahama K (January 2011). "The potent inhibitory effect of tipepidine on marble-burying behavior in mice". Behavioural Brain Research. 216 (1): 308–312. doi:10.1016/j.bbr.2010.08.010. PMID 20713091. S2CID 21118027. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:12" class="footnote-back-ref">↩</a></p></li> <li id="fn:13"><p>Sasaki T, Hashimoto K, Tachibana M, Kurata T, Okawada K, Ishikawa M, et al. (2014). "Tipepidine in children with attention deficit/hyperactivity disorder: a 4-week, open-label, preliminary study". Neuropsychiatric Disease and Treatment. 10: 147–151. doi:10.2147/NDT.S58480. PMC 3908907. PMID 24493927. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3908907" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3908907</a> <a href="#fnref:13" class="footnote-back-ref">↩</a></p></li> <li id="fn:14"><p>Hashimoto K, Sasaki T (February 2015). "Old drug tipepidine as new hope for children with ADHD". The Australian and New Zealand Journal of Psychiatry. 49 (2): 181–182. doi:10.1177/0004867414553952. PMID 25280911. S2CID 8496750. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:14" class="footnote-back-ref">↩</a></p></li> <li id="fn:15"><p>Dehbozorghi S, Bagheri S, Moradi K, Shokraee K, Mohammadi MR, Akhondzadeh S (November 2019). "Efficacy and safety of tipepidine as adjunctive therapy in children with attention-deficit/hyperactivity disorder: Randomized, double-blind, placebo-controlled clinical trial". Psychiatry and Clinical Neurosciences. 73 (11): 690–696. doi:10.1111/pcn.12913. PMID 31294924. S2CID 195879810. <a href="https://doi.org/10.1111%2Fpcn.12913" target="_blank">https://doi.org/10.1111%2Fpcn.12913</a> <a href="#fnref:15" class="footnote-back-ref">↩</a></p></li> <li id="fn:16"><p>Hamasaki R, Shirasaki T, Soeda F, Takahama K (November 2013). "Tipepidine activates VTA dopamine neuron via inhibiting dopamine D₂ receptor-mediated inward rectifying K⁺ current". Neuroscience. 252: 24–34. doi:10.1016/j.neuroscience.2013.07.044. PMID 23896570. S2CID 207253362. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:16" class="footnote-back-ref">↩</a></p></li> <li id="fn:17"><p>Hamao K, Kawaura K, Soeda F, Hamasaki R, Shirasaki T, Takahama K (May 2015). "Tipepidine increases dopamine level in the nucleus accumbens without methamphetamine-like behavioral sensitization". Behavioural Brain Research. 284: 118–124. doi:10.1016/j.bbr.2015.02.012. PMID 25687844. S2CID 22324207. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:17" class="footnote-back-ref">↩</a></p></li> </ol>