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Deoxycytidine diphosphate
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<h2 id="synthesis-of-cytidine-nucleotides">Synthesis of cytidine nucleotides</h2> <p>Deoxycytidine diphosphate is synthesized through the oxidation-reduction reaction of <a href="/facts/Cytidine_5%2527-diphosphocholine/vJM7Rgyl">cytidine 5'-diphosphocholine</a> which is catalyzed by the presence of <a href="/facts/Ribonucleoside-diphosphate_reductase/DlS3f14z">ribonucleoside-diphosphate reductase</a>.<a class="footnote-ref" id="fnref:2" href="#fn:2"><sup>2</sup></a> Additionally, ribonucleoside-diphosphate reductase is capable of binding and catalyzing both the formation of deoxyribonucleotides from ribonucleotide.<a class="footnote-ref" id="fnref:3" href="#fn:3"><sup>3</sup></a> </p> <h2 id="see-also">See also</h2> <ul><li><a href="/facts/DNA/nB89Iauz">DNA</a></li> <li><a href="/facts/Cofactor_(biochemistry)/AGo0PCUU">Cofactor</a></li> <li><a href="/facts/Cytosine/JW20j33u">Cytosine</a></li></ul> <h2 id="further-reading">Further reading</h2> <ul><li>Kennedy, Eugene P.; Louise Fencil Borkenhagen; Sylvia Wagner Smith (1959). <a href="http://www.jbc.org/content/234/8/1998.full.pdf+html">"Possible Metabolic Functions of Deoxycytidine Diphosphate Choline and Deoxycytidine Diphosphate Ethanolamine"</a>. <i>Journal of Biological Chemistry</i>. 234 (8): 1998–2000. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1016%2FS0021-9258%2818%2969855-2">10.1016/S0021-9258(18)69855-2</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/13673002">13673002</a>.</li> <li>Reichard, Peter (1962). <a href="http://www.jbc.org/content/237/11/3513.full.pdf+html">"Enzymatic Synthesis of Deoxyribonucleotides: I. FORMATION OF DEOXYCYTIDINE DIPHOSPHATE FROM CYTIDINE DIPHOSPHATE WITH ENZYMES FROM ESCHERICHIA COLI"</a>. <i>Journal of Biological Chemistry</i>. 237: 3513–3519. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1016%2FS0021-9258%2819%2970849-7">10.1016/S0021-9258(19)70849-7</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/13973714">13973714</a>..</li></ul> <h2 id="references">References</h2> <ol> <li id="fn:1"><p>MeSH term, accessed Dec. 31, 2012 <a href="https://www.nlm.nih.gov/cgi/mesh/2007/MB_cgi?mode=&index=108353" target="_blank">https://www.nlm.nih.gov/cgi/mesh/2007/MB_cgi?mode=&index=108353</a> <a href="#fnref:1" class="footnote-back-ref">↩</a></p></li> <li id="fn:2"><p>Kandeel, Mahmoud; Al-Taher, Abdulla (2020-11-01). "Metabolic drug targets of the cytosine metabolism pathways in the dromedary camel (Camelus dromedarius) and blood parasite Trypanosoma evansi". Tropical Animal Health and Production. 52 (6): 3337–3358. doi:10.1007/s11250-020-02366-8. ISSN 1573-7438. PMID 32926292. S2CID 221722974. <a href="https://doi.org/10.1007/s11250-020-02366-8" target="_blank">https://doi.org/10.1007/s11250-020-02366-8</a> <a href="#fnref:2" class="footnote-back-ref">↩</a></p></li> <li id="fn:3"><p>Torrents, Eduard (2014). "Ribonucleotide reductases: essential enzymes for bacterial life". Frontiers in Cellular and Infection Microbiology. 4: 52. doi:10.3389/fcimb.2014.00052. ISSN 2235-2988. PMC 4009431. PMID 24809024. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009431" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009431</a> <a href="#fnref:3" class="footnote-back-ref">↩</a></p></li> </ol>