There is a genetic element in individual susceptibility to cellulite. Researchers have traced the genetic component of cellulite to particular polymorphisms in the angiotensin converting enzyme (ACE) and hypoxia-inducible factor 1A (HIF1a) genes. Evidence for the heredity of cellulite is supported by studies showing that both the presence and degree of cellulite is similar between females within the same family.
Cellulite can be resistant to a variety of treatments. Aside from "topical" products (creams, ointments) and injectables (collagenase), treatments for cellulite include non-invasive therapy such as mechanical suction or mechanical massage. Energy-based devices include radio frequency with deep penetration of the skin, ultrasound, cryotherapy chambers, laser and pulsed-light devices. Combinations of mechanical treatments and energy-based procedures are widely used. Ionithermie, a form of electrotherapy using electrical muscle stimulation, has been described as ineffective. More invasive 'subcision' techniques utilize a needle-sized microscalpel to cut through the causative fibrous bands of connective tissue. Subcision procedures (manual, vacuum-assisted, or laser-assisted) are performed in specialist clinics with patients given local anaesthetic.
In European populations, cellulite is thought to occur in 80–90% of post-adolescent females. Its existence as a real disorder has been challenged, and the prevailing medical opinion is that it is merely the "normal condition of many women". It is rarely seen in males.
The growing interest in cellulite has historically been linked to the growth of the cosmetic industry in the West, as well as globalization. The term was first used in the 1920s by spa and beauty services to promote their services, and began appearing in English-language publications in the late 1960s, with the earliest reference in Vogue magazine, "Like a swift migrating fish, the word cellulite has suddenly crossed the Atlantic." According to Italian researcher Martina Grimaldi, cellulite has often been pathologized as a "disease" in Western European news media, and it has been shown that French magazines promoting this misinformation are often funded by pharmaceutical companies that manufacture anti-cellulite skincare products. American journalist Susan Faludi notes that the Western beauty advertisements have attempted to portray cellulite as a symptom of women's social progress, that cellulite is caused by being a working, independent woman. Faludi writes that such messaging is motivated by a fear within the cosmetic industry that women's social progress might lead to declining profits in the beauty industry as a whole, noting that profits did decline in the 1970s and 1980s, the era of second-wave feminism.
Rossi, Ana Beatris R; Vergnanini, Andre Luiz (2000). "Cellulite: A review". Journal of the European Academy of Dermatology and Venereology. 14 (4): 251–62. doi:10.1046/j.1468-3083.2000.00016.x. PMID 11204512. S2CID 18504078. https://onlinelibrary.wiley.com/doi/abs/10.1046/j.1468-3083.2000.00016.x
Pinna, K. (2007). Nutrition and diet therapy. Belmont, CA: Wadsworth. p. 178.
Avram, Mathew M (2004). "Cellulite: A review of its physiology and treatment". Journal of Cosmetic and Laser Therapy. 6 (4): 181–5. CiteSeerX 10.1.1.506.7997. doi:10.1080/14764170410003057. PMID 16020201. S2CID 20205700. /wiki/CiteSeerX_(identifier)
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Young, V Leroy; DiBernardo, Barry E (18 May 2021). "Comparison of Cellulite Severity Scales and Imaging Methods". Aesthetic Surgery Journal. 41 (6): NP521 – NP537. doi:10.1093/asj/sjaa226. PMC 8129470. PMID 32785706. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129470
Rao, Jaggi; Gold, Michael H; Goldman, Mitchel P (2005). "A two-center, double-blinded, randomized trial testing the tolerability and efficacy of a novel therapeutic agent for cellulite reduction". Journal of Cosmetic Dermatology. 4 (2). Wiley: 96. doi:10.1111/j.1473-2165.2005.40208.x. ISSN 1473-2130. PMID 17166206. S2CID 10123904. "heredity: empirically, it has been found that the degree and presence of cellulite, as with body habitus, is often similar between females within the same family; race: Caucasian women are more likely to develop cellulite than Asian or African American women;9 /wiki/Doi_(identifier)
Rossi, Ana Beatris R; Vergnanini, Andre Luiz (2000). "Cellulite: A review". Journal of the European Academy of Dermatology and Venereology. 14 (4): 251–62. doi:10.1046/j.1468-3083.2000.00016.x. PMID 11204512. S2CID 18504078. https://onlinelibrary.wiley.com/doi/abs/10.1046/j.1468-3083.2000.00016.x
Avram, Mathew M (2004). "Cellulite: A review of its physiology and treatment". Journal of Cosmetic and Laser Therapy. 6 (4): 181–5. CiteSeerX 10.1.1.506.7997. doi:10.1080/14764170410003057. PMID 16020201. S2CID 20205700. /wiki/CiteSeerX_(identifier)
Terranova, F.; Berardesca, E.; Maibach, H. (2006). "Cellulite: Nature and aetiopathogenesis". International Journal of Cosmetic Science. 28 (3): 157–67. doi:10.1111/j.1467-2494.2006.00316.x. PMID 18489272. S2CID 15618447. https://doi.org/10.1111%2Fj.1467-2494.2006.00316.x
Bissoon, Lionel (October 2006). The Cellulite Cure. Meso Press. p. 74. ISBN 978-0-9764821-0-9. 978-0-9764821-0-9
Rossi, Ana Beatris R; Vergnanini, Andre Luiz (2000). "Cellulite: A review". Journal of the European Academy of Dermatology and Venereology. 14 (4): 251–62. doi:10.1046/j.1468-3083.2000.00016.x. PMID 11204512. S2CID 18504078. https://onlinelibrary.wiley.com/doi/abs/10.1046/j.1468-3083.2000.00016.x
Rossi, Ana Beatris R; Vergnanini, Andre Luiz (2000). "Cellulite: A review". Journal of the European Academy of Dermatology and Venereology. 14 (4): 251–62. doi:10.1046/j.1468-3083.2000.00016.x. PMID 11204512. S2CID 18504078. https://onlinelibrary.wiley.com/doi/abs/10.1046/j.1468-3083.2000.00016.x
Emanuele, E; Bertona, M; Geroldi, D (2010). "A multilocus candidate approach identifies ACE and HIF1A as susceptibility genes for cellulite". Journal of the European Academy of Dermatology and Venereology. 24 (8): 930–5. doi:10.1111/j.1468-3083.2009.03556.x. PMID 20059631. S2CID 26214159. /wiki/Doi_(identifier)
Rao, Jaggi; Gold, Michael H; Goldman, Mitchel P (2005). "A two-center, double-blinded, randomized trial testing the tolerability and efficacy of a novel therapeutic agent for cellulite reduction". Journal of Cosmetic Dermatology. 4 (2). Wiley: 96. doi:10.1111/j.1473-2165.2005.40208.x. ISSN 1473-2130. PMID 17166206. S2CID 10123904. "heredity: empirically, it has been found that the degree and presence of cellulite, as with body habitus, is often similar between females within the same family; race: Caucasian women are more likely to develop cellulite than Asian or African American women;9 /wiki/Doi_(identifier)
Rossi, Ana Beatris R; Vergnanini, Andre Luiz (2000). "Cellulite: A review". Journal of the European Academy of Dermatology and Venereology. 14 (4): 251–62. doi:10.1046/j.1468-3083.2000.00016.x. PMID 11204512. S2CID 18504078. https://onlinelibrary.wiley.com/doi/abs/10.1046/j.1468-3083.2000.00016.x
Young, V Leroy; DiBernardo, Barry E (18 May 2021). "Comparison of Cellulite Severity Scales and Imaging Methods". Aesthetic Surgery Journal. 41 (6): NP521 – NP537. doi:10.1093/asj/sjaa226. PMC 8129470. PMID 32785706. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129470
Rossi, Ana Beatris R; Vergnanini, Andre Luiz (2000). "Cellulite: A review". Journal of the European Academy of Dermatology and Venereology. 14 (4): 251–62. doi:10.1046/j.1468-3083.2000.00016.x. PMID 11204512. S2CID 18504078. https://onlinelibrary.wiley.com/doi/abs/10.1046/j.1468-3083.2000.00016.x
Young, V Leroy; DiBernardo, Barry E (18 May 2021). "Comparison of Cellulite Severity Scales and Imaging Methods". Aesthetic Surgery Journal. 41 (6): NP521 – NP537. doi:10.1093/asj/sjaa226. PMC 8129470. PMID 32785706. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129470
Young, V Leroy; DiBernardo, Barry E (18 May 2021). "Comparison of Cellulite Severity Scales and Imaging Methods". Aesthetic Surgery Journal. 41 (6): NP521 – NP537. doi:10.1093/asj/sjaa226. PMC 8129470. PMID 32785706. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129470
Rossi, Anthony M.; Katz, Bruce E. (2014). "A Modern Approach to the Treatment of Cellulite". Dermatologic Clinics. 32 (1): 51–9. doi:10.1016/j.det.2013.09.005. PMID 24267421. /wiki/Doi_(identifier)
Juhász M, Korta D, Mesinkovska NA (2018). "A Review of the Use of Ultrasound for Skin Tightening, Body Contouring, and Cellulite Reduction in Dermatology". Dermatol Surg. 44 (7): 949–963. doi:10.1097/DSS.0000000000001551. PMID 29846343. S2CID 44101405. /wiki/Doi_(identifier)
Ingargiola, Michael J.; Motakef, Saba; Chung, Michael T.; Vasconez, Henry C.; Sasaki, Gordon H. (2015). "Cryolipolysis for Fat Reduction and Body Contouring". Plastic and Reconstructive Surgery. 135 (6). Ovid Technologies (Wolters Kluwer Health): 1581–1590. doi:10.1097/prs.0000000000001236. ISSN 0032-1052. PMC 4444424. PMID 26017594. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444424
Gold, Michael H. (2012). "Cellulite – an overview of non-invasive therapy with energy-based systems". Journal der Deutschen Dermatologischen Gesellschaft. 10 (8): 553–8. doi:10.1111/j.1610-0387.2012.07950.x. PMID 22726640. S2CID 21099081. https://doi.org/10.1111%2Fj.1610-0387.2012.07950.x
Friedmann DP, Vick GL, Mishra V (2017). "Cellulite: a review with a focus on subcision". Clin Cosmet Investig Dermatol. 10: 17–23. doi:10.2147/CCID.S95830. PMC 5234561. PMID 28123311. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234561
Gold, Michael H. (2012). "Cellulite – an overview of non-invasive therapy with energy-based systems". Journal der Deutschen Dermatologischen Gesellschaft. 10 (8): 553–8. doi:10.1111/j.1610-0387.2012.07950.x. PMID 22726640. S2CID 21099081. https://doi.org/10.1111%2Fj.1610-0387.2012.07950.x
Feldman, Melissa (2018-03-09). "Ionithermie Cellulite Treatment Reviews: Does It Work?". Consumer Health Digest. Retrieved 2023-12-24. https://www.consumerhealthdigest.com/cellulite-cream-reviews/ionithermie-cellulite-treatment.html
Coleman, Kyle M.; Coleman, William P.; Benchetrit, Arie (December 2009). "Non-Invasive, External Ultrasonic Lipolysis". Seminars in Cutaneous Medicine and Surgery. 28 (4): 263–267. doi:10.1016/j.sder.2009.10.004. ISSN 1085-5629. https://dx.doi.org/10.1016/j.sder.2009.10.004
Friedmann DP, Vick GL, Mishra V (2017). "Cellulite: a review with a focus on subcision". Clin Cosmet Investig Dermatol. 10: 17–23. doi:10.2147/CCID.S95830. PMC 5234561. PMID 28123311. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234561
Emanuele, E; Bertona, M; Geroldi, D (2010). "A multilocus candidate approach identifies ACE and HIF1A as susceptibility genes for cellulite". Journal of the European Academy of Dermatology and Venereology. 24 (8): 930–5. doi:10.1111/j.1468-3083.2009.03556.x. PMID 20059631. S2CID 26214159. /wiki/Doi_(identifier)
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MedlinePlus Encyclopedia: Cellulite /wiki/MedlinePlus
Rossi, Ana Beatris R; Vergnanini, Andre Luiz (2000). "Cellulite: A review". Journal of the European Academy of Dermatology and Venereology. 14 (4): 251–62. doi:10.1046/j.1468-3083.2000.00016.x. PMID 11204512. S2CID 18504078. https://onlinelibrary.wiley.com/doi/abs/10.1046/j.1468-3083.2000.00016.x
Vogue 15 Apr 1968 110/1[non-primary source needed] /wiki/Wikipedia:No_original_research#Primary,_secondary_and_tertiary_sources
Hackett, Paul M. W.; Hayre, Christopher M. (2 December 2020). Handbook of Ethnography in Healthcare Research. Routledge. p. 166. ISBN 978-1-000-26398-5. In the text "The female body between science and guilt: The story of cellulite", Ghigi (2004) explains the role of French magazines in the construction of the concept of cellulite. It shows how two French magazines, "Votre Beaute" and "Marie Claire" have helped to show cellulite as a disease. These are two newspapers funded by pharmaceutical companies that manufacture anti-cellulite products. 978-1-000-26398-5
Faludi, Susan (18 November 2009). Backlash: The Undeclared War Against American Women. Crown. p. 213. ISBN 978-0-307-42687-1. 978-0-307-42687-1