Important distinctions exist between different types of open projects.
Projects that provide open data but don't offer open collaboration are referred to as "open access" rather than open research. Providing open data is a necessary but not sufficient condition for open research, because although the data may be used by anyone, there is no requirement for subsequent research to take place openly. For example, though there have been many calls for more open collaborative research in drug discovery and the open deposition of large amounts of data, there are very few active, openly collaborative projects in this area.
Most open research is conducted within existing research groups. Primary research data are posted which can be added to, or interpreted by, anyone who has the necessary expertise and who can therefore join the collaborative effort. Thus the "end product" of the project (which may still be subject to future expansion or modification) arises from many contributions across multiple research groups, rather than the effort of one group or individual. Open research is therefore distinct from open access in that the output of open research is prone to change with time.
Unlike open access, true open research must demonstrate live, online collaboration. Project websites that demonstrate this capability have started to become available.
In 2005, several examples arose in the area of the search for new/improved medical treatments of Neglected Diseases.
While first attempts towards opening research were primarily aimed at opening areas such as scientific data, methodologies, software and publications, now increasingly other artifacts of the scientific workflow are also tackled, such as scientific meta-data and funding ideas.
The Transparency and Openness Promotion (TOP) Committee met in 2014 to address one key element of the incentive systems: journals' procedures and policies for publication. The committee consisted of disciplinary leaders, journal editors, funding agency representatives, and disciplinary experts largely from the social and behavioral sciences. By developing shared standards for open practices across journals, the committee said it hopes to translate scientific norms and values into concrete actions and change the current incentive structures to drive researchers' behavior toward more openness. The committee said it sought to produce guidelines that (a) focus on the commonalities across disciplines, and that (b) define what aspects of the research process should be made available to the community to evaluate, critique, reuse, and extend. The committee added that the guidelines aim to help improve journal policies in order to help transparency, openness, and reproducibility "become more evident in daily practice and ultimately improve the public trust in science, and science itself."
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