Glyceraldehyde-3-phosphate dehydrogenase (ferredoxin)

In <a href="/facts/Enzymology/DSI1Fh7y">enzymology</a>, a glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) (<a href="/facts/Enzyme_Commission_number/Y5GNLRKX">EC</a> <a href="https://enzyme.expasy.org/EC/1.2.7.6">1.2.7.6</a>) is an <a href="/facts/Enzyme/DSI1Fh7y">enzyme</a> that <a href="/facts/Catalysis/LPBS7TQC">catalyzes</a> the <a href="/facts/Chemical_reaction/GpqWlKrz">chemical reaction</a>

D-glyceraldehyde-3-phosphate + H2O + 2 oxidized ferredoxin 
 
 
 
 ⇌
 
 
 {\displaystyle \rightleftharpoons }
 
 3-phospho-D-glycerate + 2 H+ + 2 reduced ferredoxin
The 3 <a href="/facts/Substrate_(biochemistry)/6MnaV19h">substrates</a> of this enzyme are <a href="/facts/D-glyceraldehyde-3-phosphate/Wy3FMLzJ">D-glyceraldehyde-3-phosphate</a>, <a href="/facts/Water/0lkXnJPK">H2O</a>, and oxidized <a href="/facts/Ferredoxin/1qJJjQHk">ferredoxin</a>, whereas its 3 <a href="/facts/Product_(chemistry)/8uCoDUdv">products</a> are <a href="/facts/3-phospho-D-glycerate/vI3TSY4D">3-phospho-D-glycerate</a>, <a href="/facts/Hydrogen_ion/6UbSyoz4">H+</a>, and reduced ferredoxin.
This enzyme belongs to the family of <a href="/facts/Oxidoreductase/neW0G5D4">oxidoreductases</a>, specifically those acting on the aldehyde or oxo group of donor with an iron-sulfur protein as acceptor. The <a href="/facts/List_of_enzymes/w2RP6EwU">systematic name</a> of this enzyme class is D-glyceraldehyde-3-phosphate:ferredoxin oxidoreductase. Other names in common use include GAPOR, glyceraldehyde-3-phosphate Fd oxidoreductase, and glyceraldehyde-3-phosphate ferredoxin reductase.

<ul><li>Mukund S, Adams MW (1995). <a href="https://doi.org/10.1074%2Fjbc.270.15.8389">"Glyceraldehyde-3-phosphate ferredoxin oxidoreductase, a novel tungsten-containing enzyme with a potential glycolytic role in the hyperthermophilic archaeon Pyrococcus furiosus"</a>. J. Biol. Chem. 270 (15): 8389–92. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1074%2Fjbc.270.15.8389">10.1074/jbc.270.15.8389</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/7721730">7721730</a>.</li>
<li>Roy R, Menon AL, Adams MW (2001). "Aldehyde Oxidoreductases from Pyrococcus furiosus". Hyperthermophilic enzymes Part B. Methods in Enzymology. Vol. 331. pp. 132–44. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1016%2FS0076-6879%2801%2931052-2">10.1016/S0076-6879(01)31052-2</a>. <a href="/facts/ISBN_(identifier)/15AdSPa9">ISBN</a> 978-0-12-182232-3. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/11265456">11265456</a>.</li></ul>

Glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) open-in-new

Glyceraldehyde-3-phosphate dehydrogenase (ferredoxin)