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HES5
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<h2 id="further-reading">Further reading</h2> <ul><li>Gazit R, Krizhanovsky V, Ben-Arie N (February 2004). "Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway". <i>Development</i>. 131 (4): 903–913. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1242%2Fdev.00982">10.1242/dev.00982</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/14757642">14757642</a>. <a href="/facts/S2CID_(identifier)/ldJsHa2Y">S2CID</a> <a href="https://api.semanticscholar.org/CorpusID:44769279">44769279</a>.</li> <li>Nakatani T, Mizuhara E, Minaki Y, Sakamoto Y, Ono Y (April 2004). <a href="https://doi.org/10.1074%2Fjbc.M311740200">"Helt, a novel basic-helix-loop-helix transcriptional repressor expressed in the developing central nervous system"</a>. <i>The Journal of Biological Chemistry</i>. 279 (16): 16356–16367. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1074%2Fjbc.M311740200">10.1074/jbc.M311740200</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/14764602">14764602</a>.</li> <li>Kamakura S, Oishi K, Yoshimatsu T, Nakafuku M, Masuyama N, Gotoh Y (June 2004). "Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling". <i>Nature Cell Biology</i>. 6 (6): 547–554. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1038%2Fncb1138">10.1038/ncb1138</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/15156153">15156153</a>. <a href="/facts/S2CID_(identifier)/ldJsHa2Y">S2CID</a> <a href="https://api.semanticscholar.org/CorpusID:36887899">36887899</a>.</li> <li>Katoh M, Katoh M (August 2004). "Identification and characterization of human HES2, HES3, and HES5 genes in silico". <i>International Journal of Oncology</i>. 25 (2): 529–534. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.3892%2Fijo.25.2.529">10.3892/ijo.25.2.529</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/15254753">15254753</a>.</li> <li>Ohtsuka T, Imayoshi I, Shimojo H, Nishi E, Kageyama R, McConnell SK (January 2006). "Visualization of embryonic neural stem cells using Hes promoters in transgenic mice". <i>Molecular and Cellular Neurosciences</i>. 31 (1): 109–122. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1016%2Fj.mcn.2005.09.006">10.1016/j.mcn.2005.09.006</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/16214363">16214363</a>. <a href="/facts/S2CID_(identifier)/ldJsHa2Y">S2CID</a> <a href="https://api.semanticscholar.org/CorpusID:35470002">35470002</a>.</li> <li>Ong CT, Cheng HT, Chang LW, Ohtsuka T, Kageyama R, Stormo GD, Kopan R (February 2006). <a href="https://doi.org/10.1074%2Fjbc.M506108200">"Target selectivity of vertebrate notch proteins. Collaboration between discrete domains and CSL-binding site architecture determines activation probability"</a>. <i>The Journal of Biological Chemistry</i>. 281 (8): 5106–5119. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1074%2Fjbc.M506108200">10.1074/jbc.M506108200</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/16365048">16365048</a>.</li> <li>Karlsson C, Brantsing C, Svensson T, Brisby H, Asp J, Tallheden T, Lindahl A (February 2007). <a href="https://doi.org/10.1002%2Fjor.20287">"Differentiation of human mesenchymal stem cells and articular chondrocytes: analysis of chondrogenic potential and expression pattern of differentiation-related transcription factors"</a>. <i>Journal of Orthopaedic Research</i>. 25 (2): 152–163. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1002%2Fjor.20287">10.1002/jor.20287</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/17072841">17072841</a>.</li> <li>Karlsson C, Jonsson M, Asp J, Brantsing C, Kageyama R, Lindahl A (March 2007). "Notch and HES5 are regulated during human cartilage differentiation". <i>Cell and Tissue Research</i>. 327 (3): 539–551. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1007%2Fs00441-006-0307-0">10.1007/s00441-006-0307-0</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/17093926">17093926</a>. <a href="/facts/S2CID_(identifier)/ldJsHa2Y">S2CID</a> <a href="https://api.semanticscholar.org/CorpusID:33749726">33749726</a>.</li></ul> <h2 id="external-links">External links</h2> <ul><li><a href="https://meshb.nlm.nih.gov/record/ui?name=HES5+protein%2C+human">HES5+protein,+human</a> at the U.S. National Library of Medicine <a href="/facts/Medical_Subject_Headings/C57g2JuF">Medical Subject Headings</a> (MeSH)</li></ul> <p><i>This article incorporates text from the <a href="/facts/United_States_National_Library_of_Medicine/Hzty0MCX">United States National Library of Medicine</a>, which is in the <a href="/facts/Public_domain/YWKMDKw4">public domain</a>.</i> </p> <h2 id="references">References</h2> <ol> <li id="fn:1"><p>Takebayashi K, Akazawa C, Nakanishi S, Kageyama R (January 1995). "Structure and promoter analysis of the gene encoding the mouse helix-loop-helix factor HES-5. Identification of the neural precursor cell-specific promoter element". The Journal of Biological Chemistry. 270 (3): 1342–1349. doi:10.1074/jbc.270.3.1342. PMID 7836401. <a href="https://doi.org/10.1074%2Fjbc.270.3.1342" target="_blank">https://doi.org/10.1074%2Fjbc.270.3.1342</a> <a href="#fnref:1" class="footnote-back-ref">↩</a></p></li> <li id="fn:2"><p>"Entrez Gene: HES5 hairy and enhancer of split 5 (Drosophila)". <a href="https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=388585" target="_blank">https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=388585</a> <a href="#fnref:2" class="footnote-back-ref">↩</a></p></li> <li id="fn:3"><p>Ohtsuka T, Sakamoto M, Guillemot F, Kageyama R (August 2001). "Roles of the basic helix-loop-helix genes Hes1 and Hes5 in expansion of neural stem cells of the developing brain". The Journal of Biological Chemistry. 276 (32): 30467–30474. doi:10.1074/jbc.M102420200. PMID 11399758. <a href="https://doi.org/10.1074%2Fjbc.M102420200" target="_blank">https://doi.org/10.1074%2Fjbc.M102420200</a> <a href="#fnref:3" class="footnote-back-ref">↩</a></p></li> <li id="fn:4"><p>Hatakeyama J, Bessho Y, Katoh K, Ookawara S, Fujioka M, Guillemot F, Kageyama R (November 2004). "Hes genes regulate size, shape and histogenesis of the nervous system by control of the timing of neural stem cell differentiation". Development. 131 (22): 5539–5550. doi:10.1242/dev.01436. hdl:2433/144732. PMID 15496443. <a href="https://doi.org/10.1242%2Fdev.01436" target="_blank">https://doi.org/10.1242%2Fdev.01436</a> <a href="#fnref:4" class="footnote-back-ref">↩</a></p></li> <li id="fn:5"><p>Liu J, Ye F, Chen H, Lü W, Zhou C, Xie X (2007). "Expression of differentiation associated protein Hes1 and Hes5 in cervical squamous carcinoma and its precursors". International Journal of Gynecological Cancer. 17 (6): 1293–1299. doi:10.1111/j.1525-1438.2007.00930.x. PMID 17388915. S2CID 25609083. <a href="https://doi.org/10.1111%2Fj.1525-1438.2007.00930.x" target="_blank">https://doi.org/10.1111%2Fj.1525-1438.2007.00930.x</a> <a href="#fnref:5" class="footnote-back-ref">↩</a></p></li> <li id="fn:6"><p>Karlsson C, Jonsson M, Asp J, Brantsing C, Kageyama R, Lindahl A (March 2007). "Notch and HES5 are regulated during human cartilage differentiation". Cell and Tissue Research. 327 (3): 539–551. doi:10.1007/s00441-006-0307-0. PMID 17093926. S2CID 33749726. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:6" class="footnote-back-ref">↩</a></p></li> </ol>