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CACNB1
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<h2 id="see-also">See also</h2> <ul><li><a href="/facts/Voltage-dependent_calcium_channel/H9nAybJJ">Voltage-dependent calcium channel</a></li></ul> <h2 id="further-reading">Further reading</h2> <ul><li>Williams ME, Feldman DH, McCue AF, Brenner R, Velicelebi G, Ellis SB, et al. (January 1992). "Structure and functional expression of alpha 1, alpha 2, and beta subunits of a novel human neuronal calcium channel subtype". <i>Neuron</i>. 8 (1): 71–84. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1016%2F0896-6273%2892%2990109-Q">10.1016/0896-6273(92)90109-Q</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/1309651">1309651</a>. <a href="/facts/S2CID_(identifier)/ldJsHa2Y">S2CID</a> <a href="https://api.semanticscholar.org/CorpusID:39341712">39341712</a>.</li> <li>Perez-Reyes E, Castellano A, Kim HS, Bertrand P, Baggstrom E, Lacerda AE, et al. (January 1992). <a href="https://doi.org/10.1016%2FS0021-9258%2818%2946015-2">"Cloning and expression of a cardiac/brain beta subunit of the L-type calcium channel"</a>. <i>The Journal of Biological Chemistry</i>. 267 (3): 1792–1797. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1016%2FS0021-9258%2818%2946015-2">10.1016/S0021-9258(18)46015-2</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/1370480">1370480</a>.</li> <li>Powers PA, Liu S, Hogan K, Gregg RG (November 1992). <a href="https://doi.org/10.1016%2FS0021-9258%2818%2950042-9">"Skeletal muscle and brain isoforms of a beta-subunit of human voltage-dependent calcium channels are encoded by a single gene"</a>. <i>The Journal of Biological Chemistry</i>. 267 (32): 22967–22972. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1016%2FS0021-9258%2818%2950042-9">10.1016/S0021-9258(18)50042-9</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/1385409">1385409</a>.</li> <li>Pragnell M, Sakamoto J, Jay SD, Campbell KP (October 1991). <a href="https://doi.org/10.1016%2F0014-5793%2891%2981296-K">"Cloning and tissue-specific expression of the brain calcium channel beta-subunit"</a>. <i>FEBS Letters</i>. 291 (2): 253–258. <a href="/facts/Bibcode_(identifier)/9HtdQSGB">Bibcode</a>:<a href="https://ui.adsabs.harvard.edu/abs/1991FEBSL.291..253P">1991FEBSL.291..253P</a>. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1016%2F0014-5793%2891%2981296-K">10.1016/0014-5793(91)81296-K</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/1657644">1657644</a>. <a href="/facts/S2CID_(identifier)/ldJsHa2Y">S2CID</a> <a href="https://api.semanticscholar.org/CorpusID:84984587">84984587</a>.</li> <li>Collin T, Wang JJ, Nargeot J, Schwartz A (June 1993). <a href="https://doi.org/10.1161%2F01.res.72.6.1337">"Molecular cloning of three isoforms of the L-type voltage-dependent calcium channel beta subunit from normal human heart"</a>. <i>Circulation Research</i>. 72 (6): 1337–1344. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1161%2F01.res.72.6.1337">10.1161/01.res.72.6.1337</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/7916667">7916667</a>.</li> <li>Fukuda K, Kaneko S, Yada N, Kikuwaka M, Akaike A, Satoh M (October 1996). "Cyclic AMP-dependent modulation of N- and Q-type Ca2+ channels expressed in Xenopus oocytes". <i>Neuroscience Letters</i>. 217 (1): 13–16. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1016%2F0304-3940%2896%2913055-X">10.1016/0304-3940(96)13055-X</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/8905728">8905728</a>. <a href="/facts/S2CID_(identifier)/ldJsHa2Y">S2CID</a> <a href="https://api.semanticscholar.org/CorpusID:40498858">40498858</a>.</li> <li>Gregg RG, Messing A, Strube C, Beurg M, Moss R, Behan M, et al. (November 1996). <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC19477">"Absence of the beta subunit (cchb1) of the skeletal muscle dihydropyridine receptor alters expression of the alpha 1 subunit and eliminates excitation-contraction coupling"</a>. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. 93 (24): 13961–13966. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1073%2Fpnas.93.24.13961">10.1073/pnas.93.24.13961</a>. <a href="/facts/PMC_(identifier)/dX1zMt71">PMC</a> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC19477">19477</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/8943043">8943043</a>.</li> <li>Brice NL, Dolphin AC (March 1999). <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2269176">"Differential plasma membrane targeting of voltage-dependent calcium channel subunits expressed in a polarized epithelial cell line"</a>. <i>The Journal of Physiology</i>. 515 (Pt 3): 685–694. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1111%2Fj.1469-7793.1999.685ab.x">10.1111/j.1469-7793.1999.685ab.x</a>. <a href="/facts/PMC_(identifier)/dX1zMt71">PMC</a> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2269176">2269176</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/10066897">10066897</a>.</li> <li>Lie AA, Blümcke I, Volsen SG, Wiestler OD, Elger CE, Beck H (1999). "Distribution of voltage-dependent calcium channel beta subunits in the hippocampus of patients with temporal lobe epilepsy". <i>Neuroscience</i>. 93 (2): 449–456. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1016%2FS0306-4522%2899%2900162-1">10.1016/S0306-4522(99)00162-1</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/10465427">10465427</a>. <a href="/facts/S2CID_(identifier)/ldJsHa2Y">S2CID</a> <a href="https://api.semanticscholar.org/CorpusID:12890647">12890647</a>.</li> <li>Hogan K, Greg RG, Powers PA (December 1999). "Structure and alternative splicing of the gene encoding the human beta1 subunit of voltage dependent calcium channels". <i>Neuroscience Letters</i>. 277 (2): 111–114. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1016%2FS0304-3940%2899%2900851-4">10.1016/S0304-3940(99)00851-4</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/10624822">10624822</a>. <a href="/facts/S2CID_(identifier)/ldJsHa2Y">S2CID</a> <a href="https://api.semanticscholar.org/CorpusID:32210526">32210526</a>.</li> <li>Finlin BS, Crump SM, Satin J, Andres DA (November 2003). <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC283615">"Regulation of voltage-gated calcium channel activity by the Rem and Rad GTPases"</a>. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. 100 (24): 14469–14474. <a href="/facts/Bibcode_(identifier)/9HtdQSGB">Bibcode</a>:<a href="https://ui.adsabs.harvard.edu/abs/2003PNAS..10014469F">2003PNAS..10014469F</a>. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1073%2Fpnas.2437756100">10.1073/pnas.2437756100</a>. <a href="/facts/PMC_(identifier)/dX1zMt71">PMC</a> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC283615">283615</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/14623965">14623965</a>.</li> <li>Navarro-Lérida I, Martínez Moreno M, Roncal F, Gavilanes F, Albar JP, Rodríguez-Crespo I (February 2004). "Proteomic identification of brain proteins that interact with dynein light chain LC8". <i>Proteomics</i>. 4 (2): 339–346. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1002%2Fpmic.200300528">10.1002/pmic.200300528</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/14760703">14760703</a>. <a href="/facts/S2CID_(identifier)/ldJsHa2Y">S2CID</a> <a href="https://api.semanticscholar.org/CorpusID:8868600">8868600</a>.</li> <li>Foell JD, Balijepalli RC, Delisle BP, Yunker AM, Robia SL, Walker JW, et al. (April 2004). "Molecular heterogeneity of calcium channel beta-subunits in canine and human heart: evidence for differential subcellular localization". <i>Physiological Genomics</i>. 17 (2): 183–200. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1152%2Fphysiolgenomics.00207.2003">10.1152/physiolgenomics.00207.2003</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/14762176">14762176</a>. <a href="/facts/S2CID_(identifier)/ldJsHa2Y">S2CID</a> <a href="https://api.semanticscholar.org/CorpusID:38889757">38889757</a>.</li> <li>Lim J, Hao T, Shaw C, Patel AJ, Szabó G, Rual JF, et al. (May 2006). <a href="https://doi.org/10.1016%2Fj.cell.2006.03.032">"A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration"</a>. <i>Cell</i>. 125 (4): 801–814. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1016%2Fj.cell.2006.03.032">10.1016/j.cell.2006.03.032</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/16713569">16713569</a>. <a href="/facts/S2CID_(identifier)/ldJsHa2Y">S2CID</a> <a href="https://api.semanticscholar.org/CorpusID:13709685">13709685</a>.</li> <li>Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, et al. (November 2006). <a href="https://doi.org/10.1016%2Fj.cell.2006.09.026">"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks"</a>. <i>Cell</i>. 127 (3): 635–648. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1016%2Fj.cell.2006.09.026">10.1016/j.cell.2006.09.026</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/17081983">17081983</a>. <a href="/facts/S2CID_(identifier)/ldJsHa2Y">S2CID</a> <a href="https://api.semanticscholar.org/CorpusID:7827573">7827573</a>.</li></ul> <h2 id="external-links">External links</h2> <ul><li><a href="https://meshb.nlm.nih.gov/record/ui?name=CACNB1+protein%2C+human">CACNB1+protein,+human</a> at the U.S. National Library of Medicine <a href="/facts/Medical_Subject_Headings/C57g2JuF">Medical Subject Headings</a> (MeSH)</li> <li>Human <a href="https://genome.ucsc.edu/cgi-bin/hgTracks?db=hg38&singleSearch=knownCanonical&position=CACNB1"><i>CACNB1</i></a> genome location and <a href="https://genome.ucsc.edu/cgi-bin/hgGene?db=hg38&hgg_type=knownGene&hgg_gene=CACNB1"><i>CACNB1</i></a> gene details page in the <a href="/facts/UCSC_Genome_Browser/kwumPyLb">UCSC Genome Browser</a>.</li></ul> <p><i>This article incorporates text from the <a href="/facts/United_States_National_Library_of_Medicine/Hzty0MCX">United States National Library of Medicine</a>, which is in the <a href="/facts/Public_domain/YWKMDKw4">public domain</a>.</i> </p> <h2 id="references">References</h2> <ol> <li id="fn:1"><p>Gregg RG, Powers PA, Hogan K (January 1993). "Assignment of the human gene for the beta subunit of the voltage-dependent calcium channel (CACNLB1) to chromosome 17 using somatic cell hybrids and linkage mapping". Genomics. 15 (1): 185–187. doi:10.1006/geno.1993.1029. PMID 8381767. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:1" class="footnote-back-ref">↩</a></p></li> <li id="fn:2"><p>Iles DE, Segers B, Sengers RC, Monsieurs K, Heytens L, Halsall PJ, et al. (July 1993). "Genetic mapping of the beta 1- and gamma-subunits of the human skeletal muscle L-type voltage-dependent calcium channel on chromosome 17q and exclusion as candidate genes for malignant hyperthermia susceptibility". Human Molecular Genetics. 2 (7): 863–868. doi:10.1093/hmg/2.7.863. PMID 8395940. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:2" class="footnote-back-ref">↩</a></p></li> <li id="fn:3"><p>"CACNB1 calcium channel, voltage-dependent, beta 1 subunit". Entrez Gene. <a href="https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=782" target="_blank">https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=782</a> <a href="#fnref:3" class="footnote-back-ref">↩</a></p></li> <li id="fn:4"><p>"CACNB1 calcium channel, voltage-dependent, beta 1 subunit". Entrez Gene. <a href="https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=782" target="_blank">https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=782</a> <a href="#fnref:4" class="footnote-back-ref">↩</a></p></li> <li id="fn:5"><p>"CACNB1 Gene: Diseases". GeneCards. <a href="https://www.genecards.org/cgi-bin/carddisp.pl?gene=CACNB1#diseases" target="_blank">https://www.genecards.org/cgi-bin/carddisp.pl?gene=CACNB1#diseases</a> <a href="#fnref:5" class="footnote-back-ref">↩</a></p></li> </ol>