Although highly toxic to cats, permethrin is recommended as protection against mosquitoes for clothing, gear, or bed nets. In an earlier report, the CDC found oil of lemon eucalyptus to be more effective than other plant-based treatments, with a similar effectiveness to low concentrations of DEET. However, a 2006 published study found in both cage and field studies that a product containing 40% oil of lemon eucalyptus was just as effective as products containing high concentrations of DEET. Research has also found that neem oil is mosquito repellent for up to 12 hours. Citronella oil's mosquito repellency has also been verified by research, including effectiveness in repelling Aedes aegypti, but requires reapplication after 30 to 60 minutes.
Children may be at greater risk for adverse reactions to repellents, in part, because their exposure may be greater.
Children can be at greater risk of accidental eye contact or ingestion.
As with chemical exposures in general, pregnant women should take care to avoid exposures to repellents when practical, as the fetus may be vulnerable.
Some experts also recommend against applying chemicals such as DEET and sunscreen simultaneously since that would increase DEET penetration. Canadian researcher, Xiaochen Gu, a professor at the University of Manitoba's faculty of Pharmacy who led a study about mosquitos, advises that DEET should be applied 30 or more minutes later. Gu also recommends insect repellent sprays instead of lotions which are rubbed into the skin "forcing molecules into the skin".
The EPA states that citronella oil shows little or no toxicity and has been used as a topical insect repellent for 60 years. However, the EPA also states that citronella may irritate skin and cause dermatitis in certain individuals. Canadian regulatory authorities concern with citronella based repellents is primarily based on data-gaps in toxicology, not on incidents.
Within countries of the European Union, implementation of Regulation 98/8/EC, commonly referred to as the Biocidal Products Directive, has severely limited the number and type of insect repellents available to European consumers. Only a small number of active ingredients have been supported by manufacturers in submitting dossiers to the EU Authorities.
In general, only formulations containing DEET, icaridin (sold under the trade name Saltidin and formerly known as Bayrepel or KBR3023), IR3535 and citriodiol (p-menthane-3,8-diol) are available. Most "natural" insect repellents such as citronella, neem oil, and herbal extracts are no longer permitted for sale as insect repellents in the EU due to their lack of effectiveness; this does not preclude them from being sold for other purposes, as long as the label does not indicate they are a biocide (insect repellent).
Many other studies have also investigated the potential of natural compounds from plants as insect repellents. Moreover, there are many preparations from naturally occurring sources that have been used as a repellent to certain insects. Some of these act as insecticides while others are only repellent. Below is a list of some natural products with repellent activity:
People can reduce the number of mosquito bites they receive (to a greater or lesser degree) by:
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Natural & Alternative Mosquito Repellents
https://www.webmd.com/allergies/alternative-mosquito-repellents
Natural & Alternative Mosquito Repellents
https://www.webmd.com/allergies/alternative-mosquito-repellents
Natural & Alternative Mosquito Repellents
https://www.webmd.com/allergies/alternative-mosquito-repellents
Micro Wave: Why Mosquitoes Bite You More Than Your Friends https://www.npr.org/transcripts/911212751
Micro Wave: Why Mosquitoes Bite You More Than Your Friends https://www.npr.org/transcripts/911212751
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