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Morgan Sheng
open-in-new
<h2 id="education">Education</h2> <p>Sheng received a PhD in molecular genetics from <a href="/facts/Harvard_University/Lhy9L1cx">Harvard University</a>. </p> <h2 id="career">Career</h2> <p>His postdoc was performed at the <a href="/facts/University_of_California%2c_San_Francisco/tPU2yHuW">University of California, San Francisco</a>.<a class="footnote-ref" id="fnref:5" href="#fn:5"><sup>5</sup></a> Following that, Sheng was an assistant professor and associate professor at the <a href="/facts/Massachusetts_General_Hospital/SsCtKfrU">Massachusetts General Hospital</a> and <a href="/facts/Harvard_Medical_School/jlqWerKX">Harvard Medical School</a>, an investigator at the <a href="/facts/Howard_Hughes_Medical_Institute/YEu3w6qy">Howard Hughes Medical Institute</a>,<a class="footnote-ref" id="fnref:6" href="#fn:6"><sup>6</sup></a> professor of neuroscience at Massachusetts Institute of Technology, and vice president of neuroscience at <a href="/facts/Genentech/DPahQBr4">Genentech</a>.<a class="footnote-ref" id="fnref:7" href="#fn:7"><sup>7</sup></a><a class="footnote-ref" id="fnref:8" href="#fn:8"><sup>8</sup></a><a class="footnote-ref" id="fnref:9" href="#fn:9"><sup>9</sup></a> His research has focused on pathogenic mechanisms of neurodegenerative diseases and molecular cellular biology of synapses and synaptic plasticity.<a class="footnote-ref" id="fnref:10" href="#fn:10"><sup>10</sup></a> </p> <h2 id="honors-and-awards">Honors and awards</h2> <ul><li>2023: Member, <a href="/facts/National_Academy_of_Medicine/FdIo0Nd4">National Academy of Medicine</a><a class="footnote-ref" id="fnref:11" href="#fn:11"><sup>11</sup></a><a class="footnote-ref" id="fnref:12" href="#fn:12"><sup>12</sup></a></li> <li>2020: Julius Axelrod Prize, <a href="/facts/Society_for_Neuroscience/LPxz9w6q">Society for Neuroscience</a><a class="footnote-ref" id="fnref:13" href="#fn:13"><sup>13</sup></a><a class="footnote-ref" id="fnref:14" href="#fn:14"><sup>14</sup></a></li> <li>2010: Honorary fellow, <a href="/facts/Corpus_Christi_College%2c_Oxford/9xIA55ER">University of Oxford Corpus Christi College</a></li> <li>2009: Fellow, <a href="/facts/Academy_of_Medical_Sciences_(United_Kingdom)/1Gp8XQl1">Academy of Medical Sciences</a><a class="footnote-ref" id="fnref:15" href="#fn:15"><sup>15</sup></a></li> <li>2007: <a href="/facts/Fellow_of_the_Royal_Society/cWs8TdC5">Fellow</a>, <a href="/facts/Royal_Society/KI5yXCuV">Royal Society</a><a class="footnote-ref" id="fnref:16" href="#fn:16"><sup>16</sup></a></li> <li>2006: Neuronal Plasticity Prize, Fondation IPSEN</li> <li>2005: Outstanding Achievement Award, Neuroscience Division, Society of Chinese Bioscientists in America</li> <li>2004: Fellow, <a href="/facts/American_Association_for_the_Advancement_of_Science/zfWYugCg">American Association for the Advancement of Science</a></li> <li>1999: Young Investigator Award, Society for Neuroscience</li> <li>1995: Member, Society for Neuroscience</li></ul> <h2 id="selected-publications">Selected publications</h2> <ul><li>Sheng, Morgan; <a href="/facts/Michael_E._Greenberg/JA0RWMYQ">Greenberg, Michael E.</a> (1 April 1990). <a href="https://www.sciencedirect.com/science/article/abs/pii/089662739090106P">"The regulation and function of c-fos and other immediate early genes in the nervous system"</a>. <i><a href="/facts/Neuron_(journal)/KaDy3oqf">Neuron</a></i>. 4 (4). <a href="/facts/Cell_Press/pRgSUENP">Cell Press</a>: 477–485. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1016%2F0896-6273%2890%2990106-P">10.1016/0896-6273(90)90106-P</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/1969743">1969743</a>. Retrieved 1 November 2023.</li> <li><a href="/facts/Eunjoon_Kim/98y099Nq">Kim, Eunjoon</a>; Sheng, Morgan (1 October 2004). <a href="https://www.nature.com/articles/nrn1517">"PDZ domain proteins of synapses"</a>. <i><a href="/facts/Nature_Reviews_Neuroscience/zlapRAIb">Nature Reviews Neuroscience</a></i>. 5 (10): 771–781. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1038%2Fnrn1517">10.1038/nrn1517</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/15378037">15378037</a>. Retrieved 1 November 2023.</li> <li>Sheng, Morgan; Thompson, Margaret A.; <a href="/facts/Michael_E._Greenberg/JA0RWMYQ">Greenberg, Michael E.</a> (7 June 1991). <a href="https://www.science.org/doi/abs/10.1126/science.1646483">"CREB: a Ca2+-Regulated Transcription Factor Phosphorylated by Calmodulin-Dependent Kinases"</a>. <i><a href="/facts/Science_(journal)/uTyzjkwD">Science</a></i>. 252 (5011): 1427–1430. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1126%2Fscience.1646483">10.1126/science.1646483</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/1646483">1646483</a>. Retrieved 1 November 2023.</li> <li>Morgan, Sheng; Cummings, Jennifer; Roldan, Leslie Ann; <a href="/facts/Yuh_Nung_Jan/epYmyXNX">Jan, Yuh Nung</a>; <a href="/facts/Lily_Jan/PToEgkDD">Jan, Lily Yeh</a> (10 March 1994). <a href="https://www.nature.com/articles/368144a0">"Changing subunit composition of heteromeric NMDA receptors during development of rat cortex"</a>. <i><a href="/facts/Nature_(journal)/XmlJXkFx">Nature</a></i>. 368 (6467). <a href="/facts/Nature_Portfolio/eTRtG9m7">Nature Publishing Group UK</a>: 144–147. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1038%2F368144a0">10.1038/368144a0</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/8139656">8139656</a>. Retrieved 1 November 2023.</li> <li>Li, Zheng; Okamoto, Ken-Ichi; <a href="/facts/Yasunori_Hayashi/c9b1B3UH">Hayashi, Yasunori</a>; Sheng, Morgan (17 December 2004). <a href="https://doi.org/10.1016%2Fj.cell.2004.11.003">"The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses"</a>. <i><a href="/facts/Cell_(journal)/426bf9ue">Cell</a></i>. 119 (6). <a href="/facts/Elsevier/jkPSAEmR">Elsevier</a>: 873–887. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1016%2Fj.cell.2004.11.003">10.1016/j.cell.2004.11.003</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/15607982">15607982</a>.</li></ul> <h2 id="see-also">See also</h2> <ul><li><a href="/facts/Paul_Blainey/IaredHQL">Paul Blainey</a></li> <li><a href="/facts/Feng_Zhang/aEF0flUr">Feng Zhang</a></li> <li><a href="/facts/Eunjoon_Kim/98y099Nq">Eunjoon Kim</a></li> <li><a href="/facts/Steven_Hyman/P3yoU6oG">Steven Hyman</a></li></ul> <h2 id="external-links">External links</h2> <ul><li><a href="https://www.gene.com/stories/a-mind-for-the-brain">A Mind for the Brain</a>, <a href="/facts/Genentech/DPahQBr4">Genentech</a></li> <li><a href="https://neuromab.ucdavis.edu/advisoryBoard.cfm">UC Davis/NIH NeuroMab Facility Advisory Board</a></li></ul> <h2 id="references">References</h2> <ol> <li id="fn:1"><p>"Morgan Sheng, M.D., Ph.D." Broad Institute. 2 May 2019. Retrieved 1 November 2023. <a href="https://www.broadinstitute.org/bios/morgan-sheng" target="_blank">https://www.broadinstitute.org/bios/morgan-sheng</a> <a href="#fnref:1" class="footnote-back-ref">↩</a></p></li> <li id="fn:2"><p>"Morgan Sheng". Nature Reviews Drug Discovery. 8 (10): 766. 2009. doi:10.1038/nrd3014. PMID 19794439. Retrieved 1 November 2023. <a href="https://www.nature.com/articles/nrd3014" target="_blank">https://www.nature.com/articles/nrd3014</a> <a href="#fnref:2" class="footnote-back-ref">↩</a></p></li> <li id="fn:3"><p>"About". Broad Institute. Retrieved 1 November 2023. <a href="https://shenglab.broadinstitute.org/about" target="_blank">https://shenglab.broadinstitute.org/about</a> <a href="#fnref:3" class="footnote-back-ref">↩</a></p></li> <li id="fn:4"><p>"Strategic & Scientific Advisors". Cure Shark. Retrieved 1 November 2023. <a href="https://www.cureshank.org/scientific-advisory-board" target="_blank">https://www.cureshank.org/scientific-advisory-board</a> <a href="#fnref:4" class="footnote-back-ref">↩</a></p></li> <li id="fn:5"><p>"Co-Director of the Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard". Vanqua Bio. Retrieved 1 November 2023. <a href="https://www.vanquabio.com/team/morgan-sheng" target="_blank">https://www.vanquabio.com/team/morgan-sheng</a> <a href="#fnref:5" class="footnote-back-ref">↩</a></p></li> <li id="fn:6"><p>"Morgan Sheng" (PDF). Cell. 27 June 2018. Retrieved 1 November 2023. <a href="https://www.cell.com/neuron/pdf/S0896-6273(18)30484-7.pdf" target="_blank">https://www.cell.com/neuron/pdf/S0896-6273(18)30484-7.pdf</a> <a href="#fnref:6" class="footnote-back-ref">↩</a></p></li> <li id="fn:7"><p>"Morgan Sheng". Nature Reviews Drug Discovery. 17 (2): 88–89. 19 January 2018. doi:10.1038/nrd.2017.271. PMID 29348680. Retrieved 1 November 2023. <a href="https://www.nature.com/articles/nrd.2017.271" target="_blank">https://www.nature.com/articles/nrd.2017.271</a> <a href="#fnref:7" class="footnote-back-ref">↩</a></p></li> <li id="fn:8"><p>"Morgan Sheng, Ph.D." Simons Foundation. 21 July 2017. Retrieved 1 November 2023. <a href="https://www.sfari.org/people/morgan-sheng/" target="_blank">https://www.sfari.org/people/morgan-sheng/</a> <a href="#fnref:8" class="footnote-back-ref">↩</a></p></li> <li id="fn:9"><p>"Morgan Sheng Appointed VP Neuroscience Research at Genentech". BioPharm. 8 October 2008. Retrieved 1 November 2023. <a href="https://www.biopharminternational.com/view/morgan-sheng-appointed-vp-neuroscience-research-genentech" target="_blank">https://www.biopharminternational.com/view/morgan-sheng-appointed-vp-neuroscience-research-genentech</a> <a href="#fnref:9" class="footnote-back-ref">↩</a></p></li> <li id="fn:10"><p>"Morgan Sheng". Picower Institute for Learning and Memory. Massachusetts Institute of Technology. Retrieved 1 November 2023. <a href="https://picower.mit.edu/morgan-sheng" target="_blank">https://picower.mit.edu/morgan-sheng</a> <a href="#fnref:10" class="footnote-back-ref">↩</a></p></li> <li id="fn:11"><p>"Twelve with MIT ties elected to the National Academy of Medicine for 2023". MIT News. Massachusetts Institute of Technology. 10 October 2023. Retrieved 1 November 2023. <a href="https://news.mit.edu/2023/researchers-elected-national-academy-medicine-1010" target="_blank">https://news.mit.edu/2023/researchers-elected-national-academy-medicine-1010</a> <a href="#fnref:11" class="footnote-back-ref">↩</a></p></li> <li id="fn:12"><p>"National Academy of Medicine Elects 100 New Members". National Academy of Sciences. 9 October 2023. Retrieved 1 November 2023. <a href="https://nam.edu/national-academy-of-medicine-elects-100-new-members-2023" target="_blank">https://nam.edu/national-academy-of-medicine-elects-100-new-members-2023</a> <a href="#fnref:12" class="footnote-back-ref">↩</a></p></li> <li id="fn:13"><p>Tristan Davies (27 October 2020). "Morgan Sheng wins Julius Axelrod Prize for distinguished achievements in neuropharmacology". Department of Brain and Cognitive Sciences. Massachusetts Institute of Technology. Retrieved 1 November 2023. <a href="https://bcs.mit.edu/news/morgan-sheng-wins-julius-axelrod-prize-distinguished-achievements-neuropharmacology" target="_blank">https://bcs.mit.edu/news/morgan-sheng-wins-julius-axelrod-prize-distinguished-achievements-neuropharmacology</a> <a href="#fnref:13" class="footnote-back-ref">↩</a></p></li> <li id="fn:14"><p>"Society for Neuroscience Presents Julius Axelrod Prize to Morgan Sheng". Society for Neuroscience. 26 October 2020. Retrieved 1 November 2023. <a href="https://www.sfn.org/publications/latest-news/2020/10/26/society-for-neuroscience-presents-julius-axelrod-prize-to-morgan-sheng" target="_blank">https://www.sfn.org/publications/latest-news/2020/10/26/society-for-neuroscience-presents-julius-axelrod-prize-to-morgan-sheng</a> <a href="#fnref:14" class="footnote-back-ref">↩</a></p></li> <li id="fn:15"><p>"Fellow: Professor Morgan Sheng FRS FMedSci". Academy of Medical Sciences. 2009. Retrieved 1 November 2023. <a href="https://acmedsci.ac.uk/fellows/fellows-directory/ordinary-fellows/fellow/Professor-Morgan-Sheng-0009142" target="_blank">https://acmedsci.ac.uk/fellows/fellows-directory/ordinary-fellows/fellow/Professor-Morgan-Sheng-0009142</a> <a href="#fnref:15" class="footnote-back-ref">↩</a></p></li> <li id="fn:16"><p>"Fellowship of the Royal Society 1660–2015". London: Royal Society. Archived from the original on 2015-10-15. <a href="https://web.archive.org/web/20151015185820/https://docs.google.com/spreadsheets/d/1RVVZY00MZNrK2YCTTzVrbTFH2t3RxoAZah128gQR-NM/pubhtml" target="_blank">https://web.archive.org/web/20151015185820/https://docs.google.com/spreadsheets/d/1RVVZY00MZNrK2YCTTzVrbTFH2t3RxoAZah128gQR-NM/pubhtml</a> <a href="#fnref:16" class="footnote-back-ref">↩</a></p></li> </ol>