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Transcriptional noise
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<h2 id="notes">Notes</h2> <h2 id="references">References</h2> <ol> <li id="fn:1"><p>Raj, A; Van Oudenaarden, A (2008). "Nature, nurture, or chance: stochastic gene expression and its consequences". Cell. 135 (2): 216–26. doi:10.1016/j.cell.2008.09.050. PMC 3118044. PMID 18957198. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118044" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118044</a> <a href="#fnref:1" class="footnote-back-ref">↩</a></p></li> <li id="fn:2"><p>Golding, I; Paulsson, J; Zawilski, SM; Cox, EC (2005). "Real-time kinetics of gene activity in individual bacteria". Cell. 123 (6): 1025–36. doi:10.1016/j.cell.2005.09.031. PMID 16360033. <a href="https://doi.org/10.1016%2Fj.cell.2005.09.031" target="_blank">https://doi.org/10.1016%2Fj.cell.2005.09.031</a> <a href="#fnref:2" class="footnote-back-ref">↩</a></p></li> <li id="fn:3"><p>Chubb, JR; Trcek, T; Shenoy, SM; Singer, RH (2006). "Transcriptional pulsing of a developmental gene". Current Biology. 16 (10): 1018–25. Bibcode:2006CBio...16.1018C. doi:10.1016/j.cub.2006.03.092. PMC 4764056. PMID 16713960. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764056" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764056</a> <a href="#fnref:3" class="footnote-back-ref">↩</a></p></li> <li id="fn:4"><p>Raj, A; Peskin, CS; Tranchina, D; Vargas, DY; Tyagi, S (2006). "Stochastic mRNA synthesis in mammalian cells". PLOS Biology. 4 (10): e309. doi:10.1371/journal.pbio.0040309. PMC 1563489. PMID 17048983. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1563489" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1563489</a> <a href="#fnref:4" class="footnote-back-ref">↩</a></p></li> <li id="fn:5"><p>Huh, D.; Paulsson, J. (2010). "Non-genetic heterogeneity from stochastic partitioning at cell division". Nature Genetics. 43 (2): 95–100. doi:10.1038/ng.729. PMC 3208402. PMID 21186354. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208402" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208402</a> <a href="#fnref:5" class="footnote-back-ref">↩</a></p></li> <li id="fn:6"><p>Weinberger, L. S.; Burnett, J. C.; Toettcher, J. E.; Arkin, A. P.; Schaffer, D. V. (2005). "Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1 Tat fluctuations drive phenotypic diversity". Cell. 122 (2): 169–82. arXiv:q-bio/0608002. doi:10.1016/j.cell.2005.06.006. PMID 16051143. S2CID 8061716. <a href="/wiki/ArXiv_(identifier)" target="_blank">/wiki/ArXiv_(identifier)</a> <a href="#fnref:6" class="footnote-back-ref">↩</a></p></li> <li id="fn:7"><p>Losick, R.; Desplan, C. (2008). "Stochasticity and cell fate". Science. 320 (5872): 65–68. Bibcode:2008Sci...320...65L. doi:10.1126/science.1147888. PMC 2605794. PMID 18388284. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605794" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605794</a> <a href="#fnref:7" class="footnote-back-ref">↩</a></p></li> <li id="fn:8"><p>Lewis, K. (2010). "Persister Cells". Annual Review of Microbiology. 64: 357–372. doi:10.1146/annurev.micro.112408.134306. PMID 20528688. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:8" class="footnote-back-ref">↩</a></p></li> <li id="fn:9"><p>Blake, William J; Balázsi, Gábor; Kohanski, Michael A; Isaacs, Farren J; Murphy, Kevin F; Kuang, Yina; Cantor, Charles R; Walt, David R; Collins, James J (2006). "Phenotypic Consequences of Promoter-Mediated Transcriptional Noise". Molecular Cell. 24 (6): 853–865. doi:10.1016/j.molcel.2006.11.003. PMID 17189188. <a href="https://doi.org/10.1016%2Fj.molcel.2006.11.003" target="_blank">https://doi.org/10.1016%2Fj.molcel.2006.11.003</a> <a href="#fnref:9" class="footnote-back-ref">↩</a></p></li> <li id="fn:10"><p>Sharma, S. V.; Lee, D. Y.; Li, B.; Quinlan, M. P.; Takahashi, F.; Maheswaran, S.; McDermott, U.; Azizian, N.; Zou, L.; Fischbach, M. A.; Wong, K. K.; Brandstetter, K.; Wittner, B.; Ramaswamy, S.; Classon, M.; Settleman, J. (2010). "A chromatin-mediated reversible drug tolerant state in cancer cell subpopulations". Cell. 141 (1): 69–80. doi:10.1016/j.cell.2010.02.027. PMC 2851638. PMID 20371346. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851638" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851638</a> <a href="#fnref:10" class="footnote-back-ref">↩</a></p></li> <li id="fn:11"><p>Weinberger, A. D.; Weinberger, L. S. (2013). "Stochastic fate selection in HIV-infected patients". Cell. 155 (3): 497–9. doi:10.1016/j.cell.2013.09.039. PMID 24243007. <a href="https://doi.org/10.1016%2Fj.cell.2013.09.039" target="_blank">https://doi.org/10.1016%2Fj.cell.2013.09.039</a> <a href="#fnref:11" class="footnote-back-ref">↩</a></p></li> </ol>