Bromhexine

<h2 id="function">Function</h2>
<p>Bromhexine is intended to support the body's mechanisms for clearing <a href="/facts/Mucus/hnlBuHAy">mucus</a> from the <a href="/facts/Respiratory_tract/nnG9UEmr">respiratory tract</a>. It is secretolytic, increasing the production of <a href="/facts/Serous/LLgNVbvp">serous</a> mucus in the respiratory tract, which makes the <a href="/facts/Phlegm/YNavygDU">phlegm</a> thinner and less <a href="/facts/Viscous/QLVfrdCz">viscous</a>. This contributes to a <a href="/facts/Secretomotoric/h1VRf1NK">secretomotoric</a> effect, allowing the <a href="/facts/Cilia/C9l436HM">cilia</a> to more easily transport the phlegm out of the <a href="/facts/Lungs/gTWXI6Fj">lungs</a>. For this reason it is often added to <a href="/facts/Antitussive/2Qe0AjMx">cough syrups</a>.
</p><p>It has been shown to increase the proportion of serous bronchial secretion, making it more easily <a href="/facts/Expectorant/rw9veqmh">expectorated</a>. It is indicated as "secretolytic therapy in bronchopulmonary diseases associated with abnormal mucus secretion and impaired mucus transport".
</p><p>Bromhexine is contained in various formulations, high and low strength syrups 8 mg/5 ml, 4 mg/5 ml, tablets and soluble tablets (both with 8 mg bromhexine) and solution for oral use 10 mg/5 ml, adapted to the need of the patients. The <a href="/facts/Posology/4Rx8s7Ie">posology</a> varies with the age and weight, but there are products for all age groups from infant on. Bromhexine is well established and tolerated.
</p>
<h2 id="brand-names">Brand names</h2>
<ul><li>Barkacin</li>
<li>Benadryl Chesty/Forte</li>
<li>Bisolvon</li>
<li>Brofentol</li>
<li>Brofentol Plus</li>
<li>Bromex</li>
<li>Bromhexin</li>
<li>Bromifar</li>
<li>Broncholyte Elixir</li>
<li>Bronkris</li>
<li>Cofdex</li>
<li>Duro-Tuss Chesty/Forte</li>
<li>Dysolvon</li>
<li>Flegamina</li>
<li>Movex</li>
<li>Mucohexin</li>
<li>Mucolyte</li>
<li>Paxirasol</li>
<li>Robitussin Chesty/Forte</li>
<li>Solvex</li>
<li>Vasican</li>
<li>Ventilate Forte (combination of bromhexine and salbutamol)</li></ul>

<h2 id="references">References</h2>

<ol>
<li id="fn:1"><p>Morton I, Hall J (1999). Concise Dictionary of Pharmacological Agents. Springer. p. 55. ISBN 0-7514-0499-3. Retrieved 2009-06-03. <a href="0-7514-0499-3" target="_blank">0-7514-0499-3</a> <a href="#fnref:1" class="footnote-back-ref">↩</a></p></li>
<li id="fn:2"><p>Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 544. ISBN 9783527607495. <a href="9783527607495" target="_blank">9783527607495</a> <a href="#fnref:2" class="footnote-back-ref">↩</a></p></li>
</ol>

Bromhexine open-in-new

Bromhexine