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RNA recognition motif
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<h2 id="human-proteins-containing-this-domain">Human proteins containing this domain</h2> <p><a href="/facts/RBFOX1/LdzUhs1D">A2BP1</a>; <a href="/facts/ACF_(gene)/wMAzRJlr">ACF</a>; <a href="/facts/BOLL/BLpjapoM">BOLL</a>; <a href="/facts/BRUNOL4/N4vyWUEY">BRUNOL4</a>; BRUNOL5; BRUNOL6; CCBL2; CGI-96; <a href="/facts/CIRBP/ecYMcKLD">CIRBP</a>; <a href="/facts/CNOT4/atbs1DKp">CNOT4</a>; CPEB2; CPEB3; CPEB4; <a href="/facts/CPSF7/UxThaYLQ">CPSF7</a>; <a href="/facts/CSTF2/1XyH8WGR">CSTF2</a>; <a href="/facts/CSTF2T/Lk1HPGcy">CSTF2T</a>; <a href="/facts/CUGBP1/706BzkVD">CUGBP1</a>; <a href="/facts/CUGBP2/YbwQDrwk">CUGBP2</a>; D10S102; <a href="/facts/DAZ1/Up3UyI17">DAZ1</a>; <a href="/facts/DAZ2/sFkUBvdE">DAZ2</a>; <a href="/facts/DAZ3/JbFNNzFh">DAZ3</a>; DAZ4; <a href="/facts/DAZAP1/XQJnFShh">DAZAP1</a>; <a href="/facts/DAZL/6wfGXuzA">DAZL</a>; DNAJC17; DND1; EIF3S4; EIF3S9; <a href="/facts/EIF4B/uyfVrXUy">EIF4B</a>; <a href="/facts/EIF4H/4BWF1umF">EIF4H</a>; <a href="/facts/ELAVL1/aSUM4l9e">ELAVL1</a>; <a href="/facts/ELAVL2/VdFLweYp">ELAVL2</a>; <a href="/facts/ELAVL3/64v5yBaq">ELAVL3</a>; <a href="/facts/ELAVL4/auQ2vF2f">ELAVL4</a>; ENOX1; <a href="/facts/ENOX2/S9vTwSUP">ENOX2</a>; <a href="/facts/EWSR1/YEMEaKFx">EWSR1</a>; <a href="/facts/FUS_(gene)/guvWctqt">FUS</a>; <a href="/facts/FUSIP1/CdjrXhKt">FUSIP1</a>; G3BP; <a href="/facts/G3BP1/IyvKPKLe">G3BP1</a>; <a href="/facts/G3BP2/pYSMgmWG">G3BP2</a>; GRSF1; <a href="/facts/HNRNPL/4keKdURT">HNRNPL</a>; HNRPA0; <a href="/facts/HNRPA1/h0rJkpwj">HNRPA1</a>; <a href="/facts/HNRPA2B1/ChGcgd1l">HNRPA2B1</a>; <a href="/facts/HNRPA3/ePbAax4W">HNRPA3</a>; <a href="/facts/HNRPAB/NNGjodAl">HNRPAB</a>; <a href="/facts/HNRPC/kesGsFgt">HNRPC</a>; HNRPCL1; <a href="/facts/HNRPD/0srgVQEk">HNRPD</a>; <a href="/facts/HNRPDL/gapj4w43">HNRPDL</a>; <a href="/facts/HNRPF/UYDzcU1e">HNRPF</a>; <a href="/facts/HNRPH1/jwxyIahz">HNRPH1</a>; <a href="/facts/HNRPH2/onWGUxtc">HNRPH2</a>; <a href="/facts/HNRPH3/TmRNrzn5">HNRPH3</a>; HNRPL; HNRPLL; HNRPM; HNRPR; HRNBP1; HSU53209; <a href="/facts/HTATSF1/eq8M8KXV">HTATSF1</a>; <a href="/facts/IGF2BP1/kB6LobyD">IGF2BP1</a>; <a href="/facts/IGF2BP2/olVY6dQ4">IGF2BP2</a>; <a href="/facts/IGF2BP3/rpwB2g0B">IGF2BP3</a>; LARP7; <a href="/facts/MKI67IP/9tBvdfqU">MKI67IP</a>; <a href="/facts/MSI1/cxVK6jLa">MSI1</a>; <a href="/facts/MSI2/N7ILynak">MSI2</a>; MSSP-2; MTHFSD; <a href="/facts/MYEF2/jjhjNhkw">MYEF2</a>; NCBP2; <a href="/facts/Nucleolin/nIfNa9l6">NCL</a>; <a href="/facts/NOL8/grc6GogG">NOL8</a>; <a href="/facts/NONO/EHX7KKS2">NONO</a>; P14; <a href="/facts/PABPC1/GKBfnzJK">PABPC1</a>; PABPC1L; <a href="/facts/PABPC3/7tgLhVKc">PABPC3</a>; <a href="/facts/PABPC4/BIsNQVc6">PABPC4</a>; <a href="/facts/PABPC5/nPfHBF42">PABPC5</a>; <a href="/facts/PABPN1/rDg2oEce">PABPN1</a>; <a href="/facts/POLDIP3/lu1ujMbw">POLDIP3</a>; PPARGC1; <a href="/facts/PPARGC1A/dEgNkMAx">PPARGC1A</a>; <a href="/facts/PPARGC1B/NwoNaNH0">PPARGC1B</a>; <a href="/facts/PPIE_(gene)/4b9gx1Ks">PPIE</a>; <a href="/facts/PPIL4/Nr7dUDYh">PPIL4</a>; <a href="/facts/PPRC1/AxElCcba">PPRC1</a>; PSPC1; <a href="/facts/PTBP1/3cFVpd7W">PTBP1</a>; <a href="/facts/PTBP2/h18CmU8G">PTBP2</a>; <a href="/facts/PUF60/659ShIlC">PUF60</a>; <a href="/facts/RALY/BFSsfApv">RALY</a>; <a href="/facts/RALYL/H7KE4PGa">RALYL</a>; <a href="/facts/RAVER1/0uzwg40X">RAVER1</a>; RAVER2; <a href="/facts/RBM10/4Cvh2qm1">RBM10</a>; <a href="/facts/RBM11/dQNrugta">RBM11</a>; <a href="/facts/RBM12/K7Py9HQ4">RBM12</a>; RBM12B; <a href="/facts/RBM14/hjPuTgI1">RBM14</a>; <a href="/facts/RBM15/XQW52jgG">RBM15</a>; RBM15B; RBM16; <a href="/facts/RBM17/lL7RWAYb">RBM17</a>; RBM18; <a href="/facts/RBM19/p9Y1Glml">RBM19</a>; <a href="/facts/RBM22/pFAnrXn9">RBM22</a>; <a href="/facts/RBM23/WbtFL9py">RBM23</a>; RBM24; <a href="/facts/RBM25/p3t2n9H9">RBM25</a>; <a href="/facts/RBM26/aj2vHD0F">RBM26</a>; RBM27; <a href="/facts/RBM28/bN3vqSD7">RBM28</a>; <a href="/facts/RBM3/gXw5SnLM">RBM3</a>; RBM32B; <a href="/facts/RBM33/X3BCMIH2">RBM33</a>; <a href="/facts/RBM34/PPpdyH0T">RBM34</a>; RBM35A; RBM35B; RBM38; <a href="/facts/RBM39/NxA0Xapp">RBM39</a>; <a href="/facts/RBM4/zyxzSkhQ">RBM4</a>; RBM41; RBM42; RBM44; RBM45; RBM46; <a href="/facts/RBM47/aAkqRTxJ">RBM47</a>; RBM4B; <a href="/facts/RBM5/68VaCAnY">RBM5</a>; <a href="/facts/RBM7/went4Je3">RBM7</a>; <a href="/facts/RBM8A/I0XjRqKt">RBM8A</a>; <a href="/facts/RBM9/pz5utnUM">RBM9</a>; <a href="/facts/RBMS1/95JdbWzF">RBMS1</a>; RBMS2; <a href="/facts/RBMS3/NHK1XpVJ">RBMS3</a>; <a href="/facts/RBMX/YEPeBoaS">RBMX</a>; RBMX2; RBMXL2; <a href="/facts/RBMY1A1/qf08zcXc">RBMY1A1</a>; RBMY1B; RBMY1E; RBMY1F; RBMY2FP; <a href="/facts/RBPMS/o5MzpF9W">RBPMS</a>; RBPMS2; <a href="/facts/RDBP/xVsosdrk">RDBP</a>; RNPC3; RNPC4; <a href="/facts/RNPS1/BF807cjN">RNPS1</a>; ROD1; <a href="/facts/SAFB/ezKqCujK">SAFB</a>; <a href="/facts/SAFB2/pCHtsnUd">SAFB2</a>; <a href="/facts/SART3/Wfp8zyss">SART3</a>; <a href="/facts/SETD1A/423BpxGf">SETD1A</a>; <a href="/facts/SF3B6/1T5cIUHX">SF3B6</a>; <a href="/facts/SF3B4/TuKfdelK">SF3B4</a>; <a href="/facts/SFPQ/HvXaJvgm">SFPQ</a>; <a href="/facts/SFRS1/jUMRPGrU">SFRS1</a>; <a href="/facts/SFRS10/E7m5HHfo">SFRS10</a>; <a href="/facts/SFRS11/HpNFIH0o">SFRS11</a>; <a href="/facts/SFRS12/wEv7y8Ec">SFRS12</a>; SFRS15; <a href="/facts/SRSF2/bb15cCFa">SRSF2</a>; SFRS2B; <a href="/facts/SFRS3/Acb2L3SH">SFRS3</a>; <a href="/facts/SFRS4/yoFlvxG3">SFRS4</a>; <a href="/facts/SFRS5/Sh484nfB">SFRS5</a>; <a href="/facts/SFRS6/A7mBXDRE">SFRS6</a>; <a href="/facts/SFRS7/TywR0uep">SFRS7</a>; <a href="/facts/SFRS9/DGPQ3HcL">SFRS9</a>; SLIRP; SLTM; <a href="/facts/SNRP70/I9HybcHj">SNRP70</a>; <a href="/facts/SNRPA/oSJTLCJs">SNRPA</a>; <a href="/facts/SNRPB2/cUw25WfK">SNRPB2</a>; <a href="/facts/SPEN/9RQtg87C">SPEN</a>; <a href="/facts/SR140/4j3J9T63">SR140</a>; SRRP35; <a href="/facts/Sj%C3%B6gren_syndrome_antigen_B/QgQST5Gv">SSB</a>; <a href="/facts/SYNCRIP/Pb7l2oMn">SYNCRIP</a>; <a href="/facts/TAF15/vrIkdHGl">TAF15</a>; <a href="/facts/TARDBP/6yWs5erA">TARDBP</a>; <a href="/facts/THOC4/s8x5YdAG">THOC4</a>; <a href="/facts/TIA1/VCKYFuAl">TIA1</a>; <a href="/facts/TIAL1/tjospCSp">TIAL1</a>; TNRC4; TNRC6C; <a href="/facts/TRA2A/tqoxbqNJ">TRA2A</a>; TRSPAP1; TUT1; U1SNRNPBP; <a href="/facts/U2AF1/k6GNkVY3">U2AF1</a>; <a href="/facts/U2AF2/VysWf36y">U2AF2</a>; <a href="/facts/UHMK1/x6RmGbdJ">UHMK1</a>; ZCRB1; <a href="/facts/ZNF638/gX2m6LDq">ZNF638</a>; <a href="/facts/ZRSR1/mW7J4EjG">ZRSR1</a>; <a href="/facts/ZRSR2/wzvoI5Dh">ZRSR2</a>; </p> <h2 id="external-links">External links</h2> <ul><li><a href="/facts/Eukaryotic_Linear_Motif_resource/MFaIocDu">Eukaryotic Linear Motif resource</a> motif class <a href="http://elm.eu.org/elms/elmPages/LIG_ULM_U2AF65_1.html">LIG_ULM_U2AF65_1</a></li></ul> This article incorporates text from the public domain <a href="/facts/Pfam/BKJa293w">Pfam</a> and <a href="/facts/InterPro/pKwNm8t7">InterPro</a>: <a href="https://www.ebi.ac.uk/interpro/entry/IPR000504">IPR000504</a> <h2 id="references">References</h2> <ol> <li id="fn:1"><p>Swanson MS, Dreyfuss G, Pinol-Roma S (1988). "Heterogeneous nuclear ribonucleoprotein particles and the pathway of mRNA formation". Trends Biochem. Sci. 13 (3): 86–91. doi:10.1016/0968-0004(88)90046-1. PMID 3072706. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:1" class="footnote-back-ref">↩</a></p></li> <li id="fn:2"><p>Keene JD, Chambers JC, Kenan D, Martin BJ (1988). "Genomic structure and amino acid sequence domains of the human La autoantigen". J. Biol. Chem. 263 (34): 18043–51. doi:10.1016/S0021-9258(19)81321-2. PMID 3192525. <a href="https://doi.org/10.1016%2FS0021-9258%2819%2981321-2" target="_blank">https://doi.org/10.1016%2FS0021-9258%2819%2981321-2</a> <a href="#fnref:2" class="footnote-back-ref">↩</a></p></li> <li id="fn:3"><p>Davis RW, Sachs AB, Kornberg RD (1987). "A single domain of yeast poly(A)-binding protein is necessary and sufficient for RNA binding and cell viability". Mol. Cell. Biol. 7 (9): 3268–76. doi:10.1128/mcb.7.9.3268. PMC 367964. PMID 3313012. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC367964" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC367964</a> <a href="#fnref:3" class="footnote-back-ref">↩</a></p></li> <li id="fn:4"><p>Bandziulis RJ, Swanson MS, Dreyfuss G (1989). "RNA-binding proteins as developmental regulators". Genes Dev. 3 (4): 431–437. doi:10.1101/gad.3.4.431. PMID 2470643. <a href="https://doi.org/10.1101%2Fgad.3.4.431" target="_blank">https://doi.org/10.1101%2Fgad.3.4.431</a> <a href="#fnref:4" class="footnote-back-ref">↩</a></p></li> <li id="fn:5"><p>Keene JD, Query CC, Bentley RC (1989). "A common RNA recognition motif identified within a defined U1 RNA binding domain of the 70K U1 snRNP protein". Cell. 57 (1): 89–101. doi:10.1016/0092-8674(89)90175-X. PMID 2467746. S2CID 22127152. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:5" class="footnote-back-ref">↩</a></p></li> <li id="fn:6"><p>Keene JD, Chambers JC, Kenan D, Martin BJ (1988). "Genomic structure and amino acid sequence domains of the human La autoantigen". J. Biol. Chem. 263 (34): 18043–51. doi:10.1016/S0021-9258(19)81321-2. PMID 3192525. <a href="https://doi.org/10.1016%2FS0021-9258%2819%2981321-2" target="_blank">https://doi.org/10.1016%2FS0021-9258%2819%2981321-2</a> <a href="#fnref:6" class="footnote-back-ref">↩</a></p></li> <li id="fn:7"><p>Davis RW, Sachs AB, Kornberg RD (1987). "A single domain of yeast poly(A)-binding protein is necessary and sufficient for RNA binding and cell viability". Mol. Cell. Biol. 7 (9): 3268–76. doi:10.1128/mcb.7.9.3268. PMC 367964. PMID 3313012. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC367964" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC367964</a> <a href="#fnref:7" class="footnote-back-ref">↩</a></p></li> <li id="fn:8"><p>Keene JD, Query CC, Bentley RC (1989). "A common RNA recognition motif identified within a defined U1 RNA binding domain of the 70K U1 snRNP protein". Cell. 57 (1): 89–101. doi:10.1016/0092-8674(89)90175-X. PMID 2467746. S2CID 22127152. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:8" class="footnote-back-ref">↩</a></p></li> <li id="fn:9"><p>Green MR, Kielkopf CL, Lucke S (2004). "U2AF homology motifs: protein recognition in the RRM world". Genes Dev. 18 (13): 1513–1526. doi:10.1101/gad.1206204. PMC 2043112. PMID 15231733. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2043112" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2043112</a> <a href="#fnref:9" class="footnote-back-ref">↩</a></p></li> <li id="fn:10"><p>Kumar S, Birney E, Krainer AR (1993). "Analysis of the RNA-recognition motif and RS and RGG domains: conservation in metazoan pre-mRNA splicing factors". Nucleic Acids Res. 21 (25): 5803–5816. doi:10.1093/nar/21.25.5803. PMC 310458. PMID 8290338. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC310458" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC310458</a> <a href="#fnref:10" class="footnote-back-ref">↩</a></p></li> <li id="fn:11"><p>Keene JD, Kenan DJ, Query CC (1991). "RNA recognition: towards identifying determinants of specificity". Trends Biochem. Sci. 16 (6): 214–20. doi:10.1016/0968-0004(91)90088-d. PMID 1716386. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:11" class="footnote-back-ref">↩</a></p></li> <li id="fn:12"><p>Allain FH, Dominguez C, Maris C (2005). "The RNA recognition motif, a plastic RNA-binding platform to regulate post-transcriptional gene expression". FEBS J. 272 (9): 2118–31. doi:10.1111/j.1742-4658.2005.04653.x. PMID 15853797. S2CID 46680279. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:12" class="footnote-back-ref">↩</a></p></li> <li id="fn:13"><p>Teplova M, Yuan YR, Patel DJ, Malinina L, Teplov A, Phan AT, Ilin S (2006). "Structural basis for recognition and sequestration of UUU(OH) 3' temini of nascent RNA polymerase III transcripts by La, a rheumatic disease autoantigen". Mol. Cell. 21 (1): 75–85. doi:10.1016/j.molcel.2005.10.027. PMC 4689297. PMID 16387655. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689297" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689297</a> <a href="#fnref:13" class="footnote-back-ref">↩</a></p></li> </ol>