Flash vacuum pyrolysis

<h2 id="examples">Examples</h2>
<p>The technique is applied to conversions that proceed via unimolecular pathways.  2-Acetoxy<a href="/facts/Dioxane/ILtQeBxC">dioxane</a>, when heated at 425 °C converts to the highly reactive dioxene, via loss of <a href="/facts/Acetic_acid/uyBKA2Pd">acetic acid</a>.
<a class="footnote-ref" id="fnref:3" href="#fn:3"><sup>3</sup></a>  <a href="/facts/2-Furonitrile/fs31SNCD">2-Furonitrile</a> has been prepared by flash-dehydration of 2-furoic acid amide or oxime over <a href="/facts/Molecular_sieve/Lzle8J7k">molecular sieves</a>.<a class="footnote-ref" id="fnref:4" href="#fn:4"><sup>4</sup></a> The <a href="/facts/Ring_strain/seIIaK2k">strained ring</a> benzocyclobutenone has been prepared by FVP from a simple benzoyl chloride precursor.<a class="footnote-ref" id="fnref:5" href="#fn:5"><sup>5</sup></a>
</p>

<h2 id="references">References</h2>

<ol>
<li id="fn:1"><p>McNab, Hamish "Chemistry without reagents: synthetic applications of flash vacuum pyrolysis" Aldrichimica Acta 2004, volume 37, pp. 19–26.  http://www.sigmaaldrich.com/ifb/acta/v37/acta-vol37-2004.html#20 <a href="http://www.sigmaaldrich.com/ifb/acta/v37/acta-vol37-2004.html#20" target="_blank">http://www.sigmaaldrich.com/ifb/acta/v37/acta-vol37-2004.html#20</a> <a href="#fnref:1" class="footnote-back-ref">↩</a></p></li>
<li id="fn:2"><p>Wentrup, Curt "Flash (Vacuum) Pyrolysis Apparatus and Methods" Australian Journal of Chemistry 2014, volume 67, 1150–1165. doi:10.1071/CH14096 <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:2" class="footnote-back-ref">↩</a></p></li>
<li id="fn:3"><p>Matthew M. Kreilein, James C. Eppich, Leo A. Paquette "1,4-Dioxene" Org. Synth. 2005, volume 82, pp. 99. doi:10.15227/orgsyn.082.0099 <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:3" class="footnote-back-ref">↩</a></p></li>
<li id="fn:4"><p>Jacqueline A. Campbell; McDougald, Graham; McNab, Hamish; Rees, Lovat; Tyas, Richard (2007). "Laboratory-scale synthesis of nitriles by catalyzed dehydration of amides and oximes under flash vacuum pyrolysis (FVP) conditions". Synthesis. 2007 (20): 3179–3184. doi:10.1055/s-2007-990782. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:4" class="footnote-back-ref">↩</a></p></li>
<li id="fn:5"><p>Peter Schiess; Ppatibha V. Barve; Franz E. Dussy; Andreas Pfiffner (1995). "Benzocyclobutenone By Flash Vacuum Pyrolysis". Org. Synth. 72: 116. doi:10.15227/orgsyn.072.0116. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:5" class="footnote-back-ref">↩</a></p></li>
</ol>

Flash vacuum pyrolysis open-in-new

Flash vacuum pyrolysis