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Integrin alpha-1
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<h2 id="further-reading">Further reading</h2> <ul><li>Virtanen I, Korhonen M, Kariniemi AL, Gould VE, Laitinen L, Ylänne J (December 1990). "Integrins in human cells and tumors". <i>Cell Differentiation and Development</i>. 32 (3): 215–227. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1016%2F0922-3371%2890%2990034-T">10.1016/0922-3371(90)90034-T</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/2099238">2099238</a>.</li> <li>Plenz GA, Deng MC, Robenek H, Völker W (January 2003). "Vascular collagens: spotlight on the role of type VIII collagen in atherogenesis". <i>Atherosclerosis</i>. 166 (1): 1–11. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1016%2FS0021-9150%2801%2900766-3">10.1016/S0021-9150(01)00766-3</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/12482545">12482545</a>.</li> <li>Clover J, Dodds RA, Gowen M (September 1992). "Integrin subunit expression by human osteoblasts and osteoclasts in situ and in culture". <i>Journal of Cell Science</i>. 103 ( Pt 1) (1): 267–271. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1242%2Fjcs.103.1.267">10.1242/jcs.103.1.267</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/1429908">1429908</a>.</li> <li>Bodary SC, McLean JW (April 1990). <a href="https://doi.org/10.1016%2FS0021-9258%2819%2939269-5">"The integrin beta 1 subunit associates with the vitronectin receptor alpha v subunit to form a novel vitronectin receptor in a human embryonic kidney cell line"</a>. <i>The Journal of Biological Chemistry</i>. 265 (11): 5938–5941. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1016%2FS0021-9258%2819%2939269-5">10.1016/S0021-9258(19)39269-5</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/1690718">1690718</a>.</li> <li>Sonnenberg A, Linders CJ, Modderman PW, Damsky CH, Aumailley M, Timpl R (June 1990). <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2116116">"Integrin recognition of different cell-binding fragments of laminin (P1, E3, E8) and evidence that alpha 6 beta 1 but not alpha 6 beta 4 functions as a major receptor for fragment E8"</a>. <i>The Journal of Cell Biology</i>. 110 (6): 2145–2155. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1083%2Fjcb.110.6.2145">10.1083/jcb.110.6.2145</a>. <a href="/facts/PMC_(identifier)/dX1zMt71">PMC</a> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2116116">2116116</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/1693624">1693624</a>.</li> <li>Belkin VM, Belkin AM, Dol'nikova AE, Tarasova EA, Kotelianskiĭ VE (December 1991). "[Isolation and characteristics of ligand specificity of VLA-1 integrin from human smooth muscles]". <i>Biokhimiia</i>. 56 (12): 2198–2206. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/1807406">1807406</a>.</li> <li>Bank I, Roth D, Book M, Guterman A, Shnirrer I, Block R, et al. (January 1991). "Expression and functions of very late antigen 1 in inflammatory joint diseases". <i>Journal of Clinical Immunology</i>. 11 (1): 29–38. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1007%2FBF00918792">10.1007/BF00918792</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/1827128">1827128</a>. <a href="/facts/S2CID_(identifier)/ldJsHa2Y">S2CID</a> <a href="https://api.semanticscholar.org/CorpusID:6198792">6198792</a>.</li> <li>Tabibzadeh S (September 1990). "Evidence of T-cell activation and potential cytokine action in human endometrium". <i>The Journal of Clinical Endocrinology and Metabolism</i>. 71 (3): 645–649. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1210%2Fjcem-71-3-645">10.1210/jcem-71-3-645</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/2144294">2144294</a>.</li> <li>Tawil NJ, Houde M, Blacher R, Esch F, Reichardt LF, Turner DC, et al. (July 1990). <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2710132">"Alpha 1 beta 1 integrin heterodimer functions as a dual laminin/collagen receptor in neural cells"</a>. <i>Biochemistry</i>. 29 (27): 6540–6544. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1021%2Fbi00479a028">10.1021/bi00479a028</a>. <a href="/facts/PMC_(identifier)/dX1zMt71">PMC</a> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2710132">2710132</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/2169872">2169872</a>.</li> <li>Belkin VM, Belkin AM, Koteliansky VE (November 1990). <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2116325">"Human smooth muscle VLA-1 integrin: purification, substrate specificity, localization in aorta, and expression during development"</a>. <i>The Journal of Cell Biology</i>. 111 (5 Pt 1): 2159–2170. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1083%2Fjcb.111.5.2159">10.1083/jcb.111.5.2159</a>. <a href="/facts/PMC_(identifier)/dX1zMt71">PMC</a> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2116325">2116325</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/2229189">2229189</a>.</li> <li>MacDonald TT, Horton MA, Choy MY, Richman PI (April 1990). <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC502365">"Increased expression of laminin/collagen receptor (VLA-1) on epithelium of inflamed human intestine"</a>. <i>Journal of Clinical Pathology</i>. 43 (4): 313–315. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1136%2Fjcp.43.4.313">10.1136/jcp.43.4.313</a>. <a href="/facts/PMC_(identifier)/dX1zMt71">PMC</a> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC502365">502365</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/2341567">2341567</a>.</li> <li>Takada Y, Strominger JL, Hemler ME (May 1987). <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC304844">"The very late antigen family of heterodimers is part of a superfamily of molecules involved in adhesion and embryogenesis"</a>. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. 84 (10): 3239–3243. <a href="/facts/Bibcode_(identifier)/9HtdQSGB">Bibcode</a>:<a href="https://ui.adsabs.harvard.edu/abs/1987PNAS...84.3239T">1987PNAS...84.3239T</a>. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1073%2Fpnas.84.10.3239">10.1073/pnas.84.10.3239</a>. <a href="/facts/PMC_(identifier)/dX1zMt71">PMC</a> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC304844">304844</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/3033641">3033641</a>.</li> <li>Hemler ME, Huang C, Schwarz L (March 1987). <a href="https://doi.org/10.1016%2FS0021-9258%2818%2961504-2">"The VLA protein family. Characterization of five distinct cell surface heterodimers each with a common 130,000 molecular weight beta subunit"</a>. <i>The Journal of Biological Chemistry</i>. 262 (7): 3300–3309. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1016%2FS0021-9258%2818%2961504-2">10.1016/S0021-9258(18)61504-2</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/3546305">3546305</a>.</li> <li>Kono Y, Yang S, Letarte M, Roberts EA (December 1995). "Establishment of a human hepatocyte line derived from primary culture in a collagen gel sandwich culture system". <i>Experimental Cell Research</i>. 221 (2): 478–485. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1006%2Fexcr.1995.1399">10.1006/excr.1995.1399</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/7493648">7493648</a>.</li> <li>Eglinton BA, Roberton DM, Cummins AG (August 1994). "Phenotype of T cells, their soluble receptor levels, and cytokine profile of human breast milk". <i>Immunology and Cell Biology</i>. 72 (4): 306–313. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1038%2Ficb.1994.46">10.1038/icb.1994.46</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/7806264">7806264</a>. <a href="/facts/S2CID_(identifier)/ldJsHa2Y">S2CID</a> <a href="https://api.semanticscholar.org/CorpusID:25016970">25016970</a>.</li> <li>Salter DM, Godolphin JL, Gourlay MS (April 1995). <a href="https://doi.org/10.1177%2F43.4.7897185">"Chondrocyte heterogeneity: immunohistologically defined variation of integrin expression at different sites in human fetal knees"</a>. <i>The Journal of Histochemistry and Cytochemistry</i>. 43 (4): 447–457. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1177%2F43.4.7897185">10.1177/43.4.7897185</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/7897185">7897185</a>.</li> <li>Pfaff M, Aumailley M, Specks U, Knolle J, Zerwes HG, Timpl R (May 1993). "Integrin and Arg-Gly-Asp dependence of cell adhesion to the native and unfolded triple helix of collagen type VI". <i>Experimental Cell Research</i>. 206 (1): 167–176. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1006%2Fexcr.1993.1134">10.1006/excr.1993.1134</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/8387021">8387021</a>.</li> <li>Briesewitz R, Epstein MR, Marcantonio EE (February 1993). <a href="https://doi.org/10.1016%2FS0021-9258%2818%2953871-0">"Expression of native and truncated forms of the human integrin alpha 1 subunit"</a>. <i>The Journal of Biological Chemistry</i>. 268 (4): 2989–2996. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1016%2FS0021-9258%2818%2953871-0">10.1016/S0021-9258(18)53871-0</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/8428973">8428973</a>.</li> <li>Langholz O, Röckel D, Mauch C, Kozlowska E, Bank I, Krieg T, et al. (December 1995). <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2120685">"Collagen and collagenase gene expression in three-dimensional collagen lattices are differentially regulated by alpha 1 beta 1 and alpha 2 beta 1 integrins"</a>. <i>The Journal of Cell Biology</i>. 131 (6 Pt 2): 1903–1915. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1083%2Fjcb.131.6.1903">10.1083/jcb.131.6.1903</a>. <a href="/facts/PMC_(identifier)/dX1zMt71">PMC</a> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2120685">2120685</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/8557756">8557756</a>.</li> <li>Gardner H, Kreidberg J, Koteliansky V, Jaenisch R (May 1996). <a href="https://doi.org/10.1006%2Fdbio.1996.0116">"Deletion of integrin alpha 1 by homologous recombination permits normal murine development but gives rise to a specific deficit in cell adhesion"</a>. <i>Developmental Biology</i>. 175 (2): 301–313. <a href="/facts/Doi_(identifier)/muM9Etpq">doi</a>:<a href="https://doi.org/10.1006%2Fdbio.1996.0116">10.1006/dbio.1996.0116</a>. <a href="/facts/PMID_(identifier)/JlHAvMHt">PMID</a> <a href="https://pubmed.ncbi.nlm.nih.gov/8626034">8626034</a>.</li></ul> <h2 id="external-links">External links</h2> <ul><li><a href="https://meshb.nlm.nih.gov/record/ui?name=CD49a+antigen">CD49a+antigen</a> at the U.S. National Library of Medicine <a href="/facts/Medical_Subject_Headings/C57g2JuF">Medical Subject Headings</a> (MeSH)</li> <li>Human <a href="https://genome.ucsc.edu/cgi-bin/hgTracks?db=hg38&singleSearch=knownCanonical&position=ITGA1"><i>ITGA1</i></a> genome location and <a href="https://genome.ucsc.edu/cgi-bin/hgGene?db=hg38&hgg_type=knownGene&hgg_gene=ITGA1"><i>ITGA1</i></a> gene details page in the <a href="/facts/UCSC_Genome_Browser/kwumPyLb">UCSC Genome Browser</a>.</li> <li><a href="https://archive.today/20130414132042/http://cmkb.cellmigration.org/report.cgi?report=orth_overview&gene_id=3672">ITGA1</a> Info with links in the <a href="http://www.cellmigration.org/index.shtml">Cell Migration Gateway</a> <a href="https://web.archive.org/web/20141211173306/http://www.cellmigration.org/index.shtml">Archived</a> 2014-12-11 at the <a href="/facts/Wayback_Machine/nmQ3a6JC">Wayback Machine</a></li> <li><a href="https://www.ebi.ac.uk/pdbe/pdbe-kb/proteins/P56199">PDBe-KB</a> provides an overview of all the structure information available in the PDB for Human Integrin alpha-1</li></ul> <h2 id="references">References</h2> <ol> <li id="fn:1"><p>Gardner H (2014). "Integrin α1β1". I Domain Integrins. Advances in Experimental Medicine and Biology. Vol. 819. pp. 21–39. doi:10.1007/978-94-017-9153-3_2. ISBN 978-94-017-9152-6. PMID 25023165. <a href="978-94-017-9152-6" target="_blank">978-94-017-9152-6</a> <a href="#fnref:1" class="footnote-back-ref">↩</a></p></li> <li id="fn:2"><p>Reilly EC, Sportiello M, Emo KL, Amitrano AM, Jha R, Kumar AB, et al. (9 September 2021). "CD49a Identifies Polyfunctional Memory CD8 T Cell Subsets that Persist in the Lungs After Influenza Infection". Frontiers in Immunology. 12: 728669. doi:10.3389/fimmu.2021.728669. PMC 8462271. PMID 34566986. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462271" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462271</a> <a href="#fnref:2" class="footnote-back-ref">↩</a></p></li> <li id="fn:3"><p>Reilly EC, Lambert Emo K, Buckley PM, Reilly NS, Smith I, Chaves FA, et al. (June 2020). "TRM integrins CD103 and CD49a differentially support adherence and motility after resolution of influenza virus infection". Proceedings of the National Academy of Sciences of the United States of America. 117 (22): 12306–12314. doi:10.1073/pnas.1915681117. PMC 7275699. PMID 32439709. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275699" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275699</a> <a href="#fnref:3" class="footnote-back-ref">↩</a></p></li> </ol>