Campbell first became aware of his affliction with Alzheimer's while recording the music in 2009, although his wife Kim had noted memory lapses several years prior. Campbell and producer Julian Raymond decided to record one final studio album of original material while he was in good enough health, with Raymond taking the lead to contact other artists for collaboration.
At the time of the album's release, Campbell expressed interest in possibly recording further material, but thought it unlikely that he would record an entire studio album. He did, however, return to the studio long enough to produce two final albums: 2012's See You There which re-records many of his hits and was largely put to tape at the same time as Ghost on the Canvas and 2017's covers album Adiós, recorded in 2013.
Campbell promoted this album with his final concert tour.
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