The Office of the Assistant Secretary for Health and Scientific Affairs was established on January 1, 1967, following Reorganization Plan No. 3 of 1966. The new position supplanted the surgeon general as the head of the PHS, with all PHS component heads now reporting to the assistant secretary. This was seen as undermining the chain of command of the PHS Commissioned Corps, beginning a long-term shift where Commissioned Corps officers were more responsible to the agencies they were stationed in than to the corps itself.
In 1995, supervision of the agencies within PHS was shifted to report directly to the secretary of health and human services. This transformed the assistant secretary for health from a supervisory position in the direct chain of command, into an advisory one.
In 2010, the office's name was changed from Office of Public Health and Science to Office of the Assistant Secretary for Health.
As of 2018, the Office of the Assistant Secretary for Health oversees 12 core public health offices, 10 regional health offices, and 10 presidential and secretarial advisory committees.
"PHSCC Uniforms". Archived from the original on May 13, 2008. Retrieved January 19, 2008. https://web.archive.org/web/20080513175033/http://www.usphs.gov/AboutUs/uniforms.aspx
"42 USC 207. Grades, ranks, and titles of commissioned corps". Retrieved January 19, 2008. https://www.law.cornell.edu/uscode/text/42/207
"42 USC 207. Grades, ranks, and titles of commissioned corps". Retrieved January 19, 2008. https://www.law.cornell.edu/uscode/text/42/207
"Regular Corps Assimilation Program" (PDF). Archived from the original (PDF) on May 8, 2010. Retrieved January 19, 2008. https://web.archive.org/web/20100508142058/http://dcp.psc.gov/eccis/documents/CCPM23_3_7.pdf
"Records of the Office of the Assistant Secretary for Health [OASH]". National Archives. August 15, 2016. Retrieved August 29, 2020. https://www.archives.gov/research/guide-fed-records/groups/514.html
"Records of the Office of the Assistant Secretary for Health [OASH]". National Archives. August 15, 2016. Retrieved August 29, 2020. https://www.archives.gov/research/guide-fed-records/groups/514.html
History, mission, and organization of the Public Health Service. U.S. Public Health Service. 1976. pp. 3–4, 20, 22. https://books.google.com/books?id=M-n4arYE5ScC
"A Common Thread of Service: A History of the Department of Health, Education, and Welfare". U.S. Department of Health, Education, and Welfare. July 1, 1972. Secretary Cohen. Retrieved September 1, 2020 – via HHS Office of the Assistant Secretary for Planning and Evaluation. https://aspe.hhs.gov/report/common-thread-service/history-department-health-education-and-welfare
Landman, Keren (August 29, 2019). "For America's Public Health Officers, Questions of Duty and Purpose". Undark Magazine. Retrieved July 11, 2020. https://undark.org/2019/06/24/public-health-service-commissioned-corps/
Landman, Keren (August 29, 2019). "For America's Public Health Officers, Questions of Duty and Purpose". Undark Magazine. Retrieved July 11, 2020. https://undark.org/2019/06/24/public-health-service-commissioned-corps/
"Records of the Office of the Assistant Secretary for Health [OASH]". National Archives. August 15, 2016. Retrieved August 29, 2020. https://www.archives.gov/research/guide-fed-records/groups/514.html
Landman, Keren (August 29, 2019). "For America's Public Health Officers, Questions of Duty and Purpose". Undark Magazine. Retrieved July 11, 2020. https://undark.org/2019/06/24/public-health-service-commissioned-corps/
"Office of the Assistant Secretary for Health (ASH)". September 22, 2010. Archived from the original on September 22, 2010. Retrieved October 17, 2018. https://web.archive.org/web/20100922085609/http://www.hhs.gov/ophs
"Office of the Assistant Secretary for Health (OASH)". HHS.gov. March 30, 2016. Retrieved October 17, 2018. https://www.hhs.gov/ash/index.html
"Rear Admiral Arthur J. Lawrence". Council on Strategic Risks. April 24, 2020. Retrieved April 27, 2021. https://councilonstrategicrisks.org/rear-admiral-arthur-j-lawrence/
Received a recess appointment extension on January 1, 2016, under 5 U.S.C. § 3346(b)(2), to continue serving as the Acting Assistant Secretary for Health until the end of fiscal year 2016. /wiki/Title_5_of_the_United_States_Code
Received her commission and four-star rank on October 19, 2021.
"Leith J. States, M.D., M.P.H." U.S. Department of Health and Human Services. January 20, 2025. Retrieved January 25, 2025. https://www.hhs.gov/about/leadership/leith-states.html
"Dr. Dorothy Fink". U.S. Department of Health and Human Services. Retrieved May 31, 2025. https://health.gov/about-oash/oash-leadership