The club initially competed in the Dnipropetrovsk Oblast competition as FC Dnipro-2 Dnipropetrovsk .
In 1997 the club was entered into the professional leagues to compete in the Second League.
In 2004, when the PFL organised a competition for reserve teams of Premier League clubs the club moved into that competition.
In 2010 the club was entered as Dnipro's third team in the professional leagues as Dnipro-2.
Since the 2000–01 season 2nd clubs or reserve clubs could not enter the Ukrainian Cup competition ↩
Deducted 3 points by the PFL on February 9, 2011 due to failure of payment of league dues. "ДК ПФЛ позбавив шість клубів по 3 очки (Disciplinary Committee deducts 3 points from 6 clubs)" (in Ukrainian). ua-football.com. 2011-03-10. Retrieved 2011-06-04. http://www.ua-football.com/ukrainian/news/4d78d6c7.html ↩