Frontonasal process

<h2 id="nasal-processes">Nasal processes</h2>

<p>The medial nasal process (nasomedial) on the inner side of each nasal pit merge into the <a href="/facts/Intermaxillary_segment/PETdEmCp">intermaxillary segment</a> and form the <a href="/facts/Upper_lip/cUlpthmx">upper lip</a>, crest, and tip of the <a href="/facts/Human_nose/fmhw8BmP">nose</a>.<a class="footnote-ref" id="fnref:3" href="#fn:3"><sup>3</sup></a> The medial nasal processes merge with the maxillary prominences. The lateral nasal process from each side merge to form the <a href="/facts/Human_nose/fmhw8BmP">alae</a> of the <a href="/facts/Human_nose/fmhw8BmP">nose</a>.<a class="footnote-ref" id="fnref:4" href="#fn:4"><sup>4</sup></a>
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<h2 id="clinical-significance">Clinical significance</h2>
<p>Failure to fuse can cause a <a href="/facts/Cleft_lip/CoLE8Wbu">cleft lip</a>.<a class="footnote-ref" id="fnref:5" href="#fn:5"><sup>5</sup></a>
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<h2 id="genetics">Genetics</h2>
<p>There is some evidence that development involves <a href="/facts/Sonic_hedgehog/Rgp34KCx">Sonic hedgehog</a> and <a href="/facts/Fibroblast_growth_factor_8/ufaC4qhS">Fibroblast growth factor 8</a>.<a class="footnote-ref" id="fnref:6" href="#fn:6"><sup>6</sup></a>
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<p> <i>This article incorporates text in the <a href="/facts/Public_domain/YWKMDKw4">public domain</a> from <a href="https://archive.org/stream/anatomyofhumanbo1918gray#page/67/mode/2up">page 67</a> of the 20th edition of</i> <a href="/facts/Gray%2527s_Anatomy/dLMyjr2p">Gray's Anatomy</a> <i>(1918)</i>
</p>

<h2 id="external-links">External links</h2>
<ul><li><i><a href="https://syllabus.med.unc.edu/courseware/embryo_images/unit-hednk/hednk_htms/hednk027.htm">hednk-027</a></i>—Embryo Images at <a href="/facts/University_of_North_Carolina_at_Chapel_Hill/Wrd3mBWz">University of North Carolina</a></li>
<li><a href="http://www.indiana.edu/~anat550/hnanim/face/face.swf">Flash animation at indiana.edu</a></li>
<li><i><a href="http://www.emedicine.com/ent/topic30.htm#">ent/30</a></i> at <a href="/facts/EMedicine/H9gzz81K">eMedicine</a></li></ul>

<h2 id="references">References</h2>

<ol>
<li id="fn:1"><p>Sadler, T (2006). Langman's Medical Embryology. pp. 280–284. ISBN 9780781790697. <a href="9780781790697" target="_blank">9780781790697</a> <a href="#fnref:1" class="footnote-back-ref">↩</a></p></li>
<li id="fn:2"><p>Larsen, W (2001). Human embryology. pp. 365–368. ISBN 0443065837. <a href="0443065837" target="_blank">0443065837</a> <a href="#fnref:2" class="footnote-back-ref">↩</a></p></li>
<li id="fn:3"><p>Sadler, T (2006). Langman's Medical Embryology. pp. 280–284. ISBN 9780781790697. <a href="9780781790697" target="_blank">9780781790697</a> <a href="#fnref:3" class="footnote-back-ref">↩</a></p></li>
<li id="fn:4"><p>Sadler, T (2006). Langman's Medical Embryology. pp. 280–284. ISBN 9780781790697. <a href="9780781790697" target="_blank">9780781790697</a> <a href="#fnref:4" class="footnote-back-ref">↩</a></p></li>
<li id="fn:5"><p>Sadler, T (2006). Langman's Medical Embryology. pp. 280–284. ISBN 9780781790697. <a href="9780781790697" target="_blank">9780781790697</a> <a href="#fnref:5" class="footnote-back-ref">↩</a></p></li>
<li id="fn:6"><p>Abzhanov A, Cordero DR, Sen J, Tabin CJ, Helms JA (December 2007). "Cross-regulatory interactions between Fgf8 and Shh in the avian frontonasal prominence". Congenit Anom (Kyoto). 47 (4): 136–48. doi:10.1111/j.1741-4520.2007.00162.x. PMID 17988255. S2CID 16272570. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:6" class="footnote-back-ref">↩</a></p></li>
</ol>

Frontonasal process open-in-new

Frontonasal process