Conformational dynamics data bank

<p>The conformational dynamics data bank (CDDB) is a <a href="/facts/Database/VYcpkevb">database</a> about <a href="/facts/Conformational_change/q23CgKgo">conformational dynamics</a> of <a href="/facts/Immunoglobulin_heavy_chain/3H7Axuu5">heavy proteins</a> and <a href="/facts/Protein_complex/GW11Ee34">protein assemblies</a>. The CDDB is useful when used alongside static structural data to aid research into <a href="/facts/Protein_function/Jxmagu3E">protein function</a>. It is also helpful in identifying protein assemblies that are essential to <a href="/facts/Cell_(biology)/bLM9UQvy">cell function</a>.
</p><p>Analysis is carried out by <a href="/facts/Granularity/kBqMRzaj">coarse-grained computation</a> of the structures present in the <a href="/facts/Electron_microscopy_data_bank/7CbcRYmp">electron microscopy data bank</a> (EMDB). This analysis shows <a href="/facts/Thermal_fluctuations/P71QXc2l">equilibrium thermal fluctuations</a> and <a href="/facts/Elastic_and_plastic_strain/2VKo6keA">elastic strain</a> energy distributions, which allows for identification of rigid and flexible protein domains. The results also provide information on correlations in <a href="/facts/Database_of_Molecular_Motions/k0HswqsF">molecular motions</a> which can be used to identify molecular regions that are highly coupled dynamically.
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Conformational dynamics data bank open-in-new

Conformational dynamics data bank