Acyl halide

<p>An acyl halide (also known as an acid halide) is a <a href="/facts/Chemical_compound/37FXqqtv">chemical compound</a> derived from an <a href="/facts/Oxoacid/p0bMdwSx">oxoacid</a> by replacing a <a href="/facts/Hydroxyl/1Hs2QAEv">hydroxyl</a> group (−OH) with a <a href="/facts/Halide/ujYu8kGD">halide</a> group (−X, where X is a <a href="/facts/Halogen/YeFgWHeA">halogen</a>).
</p><p>In <a href="/facts/Organic_chemistry/djxhxaNg">organic chemistry</a>, the term typically refers to acyl halides of <a href="/facts/Carboxylic_acid/U4xuMosy">carboxylic acids</a> (−C(=O)OH), which contain a −C(=O)X <a href="/facts/Functional_group/GXkSPsjM">functional group</a> consisting of a <a href="/facts/Carbonyl/KJ71bo3X">carbonyl</a> group (C=O) singly bonded to a halogen atom. The general formula for such an acyl halide can be written RCOX, where R may be, for example, an <a href="/facts/Alkyl/vmEk8X4v">alkyl</a> group, CO is the carbonyl group, and X represents the halide, such as <a href="/facts/Chloride/m9NUaUDR">chloride</a>. <a href="/facts/Acyl_chloride/R4ppUXre">Acyl chlorides</a> are the most commonly encountered acyl halides, but <a href="/facts/Acetyl_iodide/9UIUblMB">acetyl iodide</a> is the one produced (transiently) on the largest scale.  Billions of kilograms are generated annually in the production of <a href="/facts/Acetic_acid/uyBKA2Pd">acetic acid</a>.
</p>

Acyl halide open-in-new

Acyl halide