Intestinal mucosal barrier

<p>The intestinal mucosal barrier, also referred to as intestinal barrier, refers to the property of the <a href="/facts/Human_gastrointestinal_tract/nK2zwqBS">intestinal mucosa</a> that ensures adequate containment of undesirable <a href="/facts/Lumen_(anatomy)/3thJT4Hf">luminal</a> contents within the intestine while preserving the ability to absorb <a href="/facts/Nutrient/34bn4skK">nutrients</a>. The separation it provides between the body and the gut prevents the uncontrolled translocation of luminal contents into the body proper. Its role in protecting the mucosal tissues and <a href="/facts/Circulatory_system/WXwudzzc">circulatory system</a> from exposure to <a href="/facts/Inflammation/Ura86MIy">pro-inflammatory molecules</a>, such as <a href="/facts/Microorganism/pysJYcE2">microorganisms</a>, <a href="/facts/Toxin/11oUNk7n">toxins</a>, and <a href="/facts/Antigen/9JlAernG">antigens</a> is vital for the maintenance of health and well-being. Intestinal mucosal barrier dysfunction has been implicated in numerous health conditions such as: <a href="/facts/Food_allergy/Nkf1e70o">food allergies</a>, <a href="/facts/Infection/182XrncP">microbial infections</a>, <a href="/facts/Irritable_bowel_syndrome/FW24EYbP">irritable bowel syndrome</a>, <a href="/facts/Inflammatory_bowel_disease/RuxcPW5A">inflammatory bowel disease</a>, <a href="/facts/Coeliac_disease/AKd5PkTc">celiac disease</a>, <a href="/facts/Metabolic_syndrome/jI70tRBv">metabolic syndrome</a>, <a href="/facts/Non-alcoholic_fatty_liver_disease/WoAmAUmV">non-alcoholic fatty liver disease</a>, <a href="/facts/Diabetes_mellitus/2xeHXbsI">diabetes</a>, and <a href="/facts/Septic_shock/yc9mgmrz">septic shock</a>.
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Intestinal mucosal barrier open-in-new

Intestinal mucosal barrier