Glibenclamide

Glibenclamide, also known as glyburide, is an <a href="/facts/Antidiabetic_medication/KIRV1BHj">antidiabetic medication</a> used to treat <a href="/facts/Type_2_diabetes/zCMXksmt">type 2 diabetes</a>. It is recommended that it be taken together with diet and exercise. It may be used with other <a href="/facts/Antidiabetic_medication/KIRV1BHj">antidiabetic medication</a>. It is not recommended for use by itself in <a href="/facts/Type_1_diabetes/IkuQadGx">type 1 diabetes</a>. It is taken <a href="/facts/Oral_administration/vNQcvLVx">by mouth</a>.
Common side effects include nausea and heartburn. Serious side effects may include <a href="/facts/Angioedema/Wpc7qnTK">angioedema</a> and <a href="/facts/Low_blood_sugar/BlAmuP6k">low blood sugar</a>. It is generally not recommended during <a href="/facts/Pregnancy/vEKYGpep">pregnancy</a> but can be used during <a href="/facts/Breastfeeding/cdWXyYDX">breastfeeding</a>. It is in the <a href="/facts/Sulfonylurea/TJd2qFH3">sulfonylureas</a> class of medications and works by increasing the release of <a href="/facts/Insulin/oXG0myt1">insulin</a> from the <a href="/facts/Pancreas/r0WPGjAq">pancreas</a>.
Glibenclamide was discovered in 1969 and approved for medical use in the United States in 1984. It is available as a <a href="/facts/Generic_medication/IF6AXDVX">generic medication</a>. In 2021, it was the 214th most commonly prescribed medication in the United States, with more than 2 million prescriptions.

Glibenclamide open-in-new

Glibenclamide