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Multicolumn countercurrent solvent gradient purification
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<p>Multicolumn countercurrent solvent gradient purification (MCSGP) is a form of <a href="/facts/Chromatography/2FrvPjNV">chromatography</a> that is used to separate or purify <a href="/facts/Biomolecule/DGvFzN7R">biomolecules</a> from complex mixtures. It was developed at the <a href="/facts/ETH_Zurich/IxHAFGUU">Swiss Federal Institute of Technology Zürich</a> by Aumann and Morbidelli. The process consists of two to six chromatographic columns which are connected to one another in such a way that as the mixture moves through the columns the compound is purified into several fractions. </p>