Padmini Rout (born 5 January 1994) is an Indian chess player. She holds the titles of International Master (IM) and Woman Grandmaster (WGM). She has won the National Women's Premier Championship five times, consecutively from 2014 to 2017 and again in 2023, and was the Asian women's champion in 2018.
Rout was honoured with the Biju Patnaik Sports Award for the year 2007 and the Ekalavya Award in 2009.