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Reference.org
Multicopy single-stranded DNA
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<p>Multicopy single-stranded DNA (msDNA) is a type of extrachromosomal <a href="/facts/Satellite_DNA/P4FMjdgB">satellite DNA</a> that consists of a single-stranded <a href="/facts/DNA/nB89Iauz">DNA</a> molecule covalently linked via a 2'-5'<a href="/facts/Phosphodiester_bond/fCjTAnxa">phosphodiester bond</a> to an internal <a href="/facts/Guanosine/P7YVKuzy">guanosine</a> of an <a href="/facts/RNA/HxPeNfNj">RNA</a> molecule. The resultant DNA/RNA chimera possesses two <a href="/facts/Stem-loop/GysAzrX5">stem-loops</a> joined by a branch similar to the branches found in <a href="/facts/RNA_splicing/a2QEvCRI">RNA splicing</a> intermediates. The coding region for msDNA, called a "<a href="/facts/Retron/kBGCQjjU">retron</a>", also encodes a type of <a href="/facts/Reverse_transcriptase/Vc1lGk8P">reverse transcriptase</a>, which is essential for msDNA synthesis. </p>