CoRR hypothesis

The CoRR hypothesis states that the location of <a href="/facts/Genetic_information/qAf4kTee">genetic information</a> in <a href="/facts/Cytoplasmic/Wa0sE6xf">cytoplasmic</a> <a href="/facts/Organelles/vhDFnGbs">organelles</a> permits regulation of its expression by the reduction-oxidation ("<a href="/facts/Redox/Pyd5RVcj">redox</a>") state of its <a href="/facts/Gene_product/GItmzEpH">gene products</a>.
CoRR is short for "co-location for redox regulation", itself a shortened form of "co-location (of gene and gene product) for (evolutionary) continuity of redox regulation of <a href="/facts/Gene_expression/alCPohLR">gene expression</a>".
CoRR was put forward explicitly in 1993 in a paper in the <a href="/facts/Journal_of_Theoretical_Biology/HKeLn54K">Journal of Theoretical Biology</a> with the title "Control of gene expression by redox potential and the requirement for chloroplast and mitochondrial genomes". The central concept had been outlined in a review of 1992. The term CoRR was introduced in 2003 in a paper in <a href="/facts/Philosophical_Transactions_of_the_Royal_Society/a0l7M7RR">Philosophical Transactions of the Royal Society</a> entitled "The function of genomes in bioenergetic organelles".

CoRR hypothesis open-in-new

CoRR hypothesis