Material Protection, Control and Accounting (MPC&A) refers to the safeguarding of nuclear assets, including nuclear fuel and weapons. In the United States, the National Nuclear Security Administration (NNSA), a component of the Department of Energy, oversees MPC&A as part of its non-proliferation program.
The United States-Russia MPC&A program began in 1944, separate and in parallel with the United States Department of Defence (DOD) Cooperative Threat Reduction Program, following the passage of the Soviet Nuclear Threat Reduction Act of 1991. It sought to improve the security of nuclear weapons and nuclear weapons' material through upgrades to material protection, material control and accounting at nuclear sites in Russia and other countries of the former Soviet Union, through cooperation between the United States Department of Energy and the Russian Federal Agency on Atomic Energy (Rosatom). The program improved the security of thousands of tons of weapons-grade nuclear material in the Former Soviet countries (FSU).