Menu
Home
People
Places
Arts
History
Plants & Animals
Science
Life & Culture
Technology
Reference.org
C1-inhibitor
open-in-new
<p>C1-inhibitor (C1-inh, C1 esterase inhibitor) is a <a href="/facts/Protease_inhibitor_(biology)/YcXcAS48">protease inhibitor</a> belonging to the <a href="/facts/Serpin/nTzzQk18">serpin</a> superfamily. Its main function is the inhibition of the <a href="/facts/Complement_system/vRSrQDUv">complement system</a> (C1r, C1s) to prevent spontaneous activation but also as the major regulator of the contact system (PK, FXIIa, and FXIa). </p>