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Reference.org
Selective receptor modulator
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<p>In the field of <a href="/facts/Pharmacology/4Rx8s7Ie">pharmacology</a>, a selective receptor modulator or SRM is a type of <a href="/facts/Drug/FFFUI9n4">drug</a> that has different effects in different tissues. An SRM may behave as an <a href="/facts/Agonist/nz8U5NNp">agonist</a> in some tissues while as an <a href="/facts/Receptor_antagonist/PuXHVNdV">antagonist</a> in others. Hence selective receptor modulators are sometimes referred to as tissue selective drugs or mixed agonists / antagonists. This tissue selective behavior is in contrast to many other drugs that behave either as agonists or antagonists regardless of the tissue in question. </p>