Congenital adrenal hyperplasia

<p>Congenital adrenal hyperplasia (CAH) is a group of <a href="/facts/Genetic_disorder/hFqt2NLn">autosomal recessive disorders</a> characterized by impaired <a href="/facts/Cortisol/5IvRV0cm">cortisol</a> synthesis. It results from the deficiency of one of the five <a href="/facts/Enzymes/DSI1Fh7y">enzymes</a> required for the <a href="/facts/Biosynthesis/aFk7Tk7f">synthesis</a> of cortisol in the <a href="/facts/Adrenal_cortex/t4EkJgdy">adrenal cortex</a>. Most of these disorders involve excessive or deficient production of <a href="/facts/Hormone/WFnBnINJ">hormones</a> such as <a href="/facts/Glucocorticoid/2P91Aj3S">glucocorticoids</a>, <a href="/facts/Mineralocorticoid/Ruj1B1Mv">mineralocorticoids</a>, or <a href="/facts/Sex_steroid/mI6bkHII">sex steroids</a>, and can alter development of <a href="/facts/Primary_sex_characteristic/c2ypY14E">primary</a> or <a href="/facts/Secondary_sex_characteristic/lV2Fl3uA">secondary sex characteristics</a> in some affected <a href="/facts/Infant/gaEL1QL4">infants</a>, children, or adults. It is one of the most common autosomal recessive disorders in humans.
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Congenital adrenal hyperplasia open-in-new

Congenital adrenal hyperplasia