Microbial pathogenesis

<p>Microbial pathogenesis is a field of <a href="/facts/Microbiology/k7udsq81">microbiology</a> that started at least as early as 1988, with the identification of the triune <a href="/facts/Falkow%2527s_criteria/7KCEr47g">Falkow's criteria</a>, aka <a href="/facts/Molecular_Koch%2527s_postulates/7KCEr47g">molecular Koch's postulates</a>. In 1996, Fredricks and Relman proposed a seven-point list of "Molecular Guidelines for Establishing Microbial Disease Causation," because of "the discovery of <a href="/facts/Nucleic_acids/2tTgcI0v">nucleic acids</a>" by <a href="/facts/Watson_and_Crick/V471Vbwb">Watson and Crick</a> "as the source of <a href="/facts/Genetic_information/qAf4kTee">genetic information</a> and as the basis for precise characterization of an <a href="/facts/Organism/j8JkL09u">organism</a>." The subsequent development of the "ability to detect and manipulate these nucleic acid molecules in microorganisms has created a powerful means for identifying previously unknown microbial pathogens and for studying the host-parasite relationship."
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Microbial pathogenesis open-in-new

Microbial pathogenesis