Lead-DBS

<p>Lead-DBS is an <a href="/facts/Open-source_software/HzTaB8E9">open-source</a> toolbox for reconstructions and modeling of <a href="/facts/Deep_brain_stimulation/STmkEI2M">Deep Brain Stimulation</a> electrodes based on pre- and postoperative <a href="/facts/Magnetic_resonance_imaging/Vh9yG9qq">MRI</a> & <a href="/facts/CT_scan/NusPJ2S8">CT</a> imaging.
</p><p>Lead-DBS is available as a <a href="/facts/MATLAB/qPjLISCk">MATLAB</a> toolbox or standalone binary for <a href="/facts/Microsoft_Windows/bwhAhuSL">Windows</a>, <a href="/facts/OS_X/Y93vVpTm">OS X</a> and <a href="/facts/Linux/9FvCKSTq">Linux</a>. Besides MATLAB code, it contains a miniforge Python environment, as well as code modules that were compiled from <a href="/facts/Fortran/m1KqjcMU">Fortran</a> and <a href="/facts/C_/Ky2No763">C</a>. Parts of its code build upon other open-source tools available to the neuroimaging community, such as <a href="/facts/Statistical_parametric_mapping/NDJ7qx6M">SPM</a>, <a href="/facts/FMRIB_Software_Library/hCMGVllw">FSL</a>, <a href="/facts/3D_Slicer/b9YfcRKg">3DSlicer</a>, OSS-DBS, <a href="/facts/FreeSurfer/wV2mL58c">FreeSurfer</a>, <a href="/facts/FieldTrip/my0aTgG1">FieldTrip</a> or Advanced Normalization tools. Lead-DBS was originally developed at the <a href="/facts/Charit%25C3%25A9/N7CFWueP">Charité Berlin</a> beginning in 2012 by <a href="/facts/Andreas_Horn/n8TAjnao">Andreas Horn</a> and has been freely available for research use under the <a href="/facts/GNU_General_Public_License/S75KhLSX">GNU General Public License</a> since 2014.  Since then, the toolbox has grown into an open-source project from an active development and user base at numerous institutions such as <a href="/facts/Mass_General_Brigham/Dt2a7m5k">Mass General Brigham</a> / <a href="/facts/Harvard_Medical_School/jlqWerKX">Harvard Medical School</a>, <a href="/facts/University_of_Cologne/PrcKaGv2">University of Cologne</a>, <a href="/facts/University_of_Luxembourg/JR9qcyB6">University of Luxembourg</a> and <a href="/facts/University_of_Melbourne/KbwoHgto">University of Melbourne</a>. According to the toolbox website, the software has been downloaded over 65,000 times and has been used in over 500 scientific publications. Funding for continued development included an <a href="/facts/Emmy_Noether_Program/0rRs8lFS">Emmy Noether</a> award by the <a href="/facts/German_Research_Foundation/fHRjppq8">German Research Foundation</a> as well as an <a href="/facts/R01_grant/G3Eytfcc">R01</a> grant by the <a href="/facts/National_Institute_of_Mental_Health/EqxY3XXy">National Institute of Mental Health</a>. Since 2014, Lead-DBS has been extended by the group analysis module Lead Group, the <a href="/facts/Connectome/X5tjEwwl">connectome</a> processing tools Lead Connectome and Lead Mapper, the intraoperative module Lead-OR, as well as an interface with the biophysical modeling toolbox OSS-DBS. In 2018 and 2023, scientific articles describing versions 2 and 3 of the software have been published, respectively.
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Lead-DBS open-in-new

Lead-DBS