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Carbon monoxide-releasing molecules
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<p>Carbon monoxide-releasing molecules (CORMs) are chemical compounds designed to release controlled amounts of <a href="/facts/Carbon_monoxide/CKuLtEMJ">carbon monoxide</a> (CO). CORMs are being developed as potential therapeutic agents to locally deliver CO to cells and tissues, thus overcoming limitations of CO gas inhalation protocols. </p><p>CO is best known for its toxicity in <a href="/facts/Carbon_monoxide_poisoning/UyjKzy4W">carbon monoxide poisoning</a> at high doses. However, CO is a <a href="/facts/Gasotransmitter/BxUDv71M">gasotransmitter</a> and supplemental low dosage of CO has been linked to therapeutic benefits. Pre-clinical research has focused on CO's <a href="/facts/Anti-inflammatory/W27poSUd">anti-inflammatory</a> activity with significant applications in cardiovascular disease, oncology, transplant surgery, and neuroprotection. </p>