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Reference.org
SOS response
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<p>The SOS response is a global transcriptional response to <a href="/facts/DNA/nB89Iauz">DNA</a> damage in <a href="/facts/Prokaryote/oYyvaDDH">prokaryotes</a>, in which the <a href="/facts/Cell_cycle/nLMT7K4r">cell cycle</a> is arrested and <a href="/facts/DNA_repair/hsURuYYq">DNA repair</a> mechanisms (error-free as well as error-prone) are induced. The regulation of this response is driven by two proteins, <a href="/facts/RecA/MPHuQLK9">RecA</a> and <a href="/facts/LexA/jPC117wA">LexA</a>. The RecA protein, stimulated by single-stranded DNA, is involved in the inactivation of the repressor (<a href="/facts/LexA/jPC117wA">LexA</a>) of SOS response genes thereby inducing the response. It is an error-prone repair system that contributes significantly to DNA changes observed in a wide range of bacterial species. </p>