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Coprine
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<p>Coprine is a <a href="/facts/Mycotoxin/11dL2teq">mycotoxin</a>. It was first isolated from <a href="/facts/Coprinopsis_atramentaria/JUlfjJhz">common inkcap</a> (<i>Coprinopsis atramentaria</i>). It occurs in mushrooms in the genera <i><a href="/facts/Coprinopsis/oWoe3W52">Coprinopsis</a></i>. When combined with <a href="/facts/Ethanol/3lCLfBSP">alcohol</a>, it causes "Coprinus syndrome".: 284 It inhibits the enzyme <a href="/facts/Aldehyde_dehydrogenase/qNWTxjtR">aldehyde dehydrogenase</a>, which is involved in the metabolism of alcohol. This inhibition leads to a buildup of <a href="/facts/Acetaldehyde/QllLbSUe">acetaldehyde</a>, causing an <a href="/facts/Alcohol_flush_reaction/YjegYSUD">alcohol flush reaction</a>. Because of this, the mushroom is commonly referred to as Tippler's Bane. </p>