Serial time-encoded amplified microscopy

<p>Time stretch microscopy, also known as serial time-encoded amplified imaging/microscopy or stretched time-encoded amplified imaging/microscopy' (STEAM), is a fast real-time optical imaging method that provides MHz frame rate, ~100 ps shutter speed, and ~30 dB (× 1000) optical image gain. Based on the photonic time stretch technique, STEAM holds world records for <a href="/facts/Shutter_speed/5CMJNBop">shutter speed</a> and <a href="/facts/Frame_rate/sbRkc9xa">frame rate</a> in continuous real-time imaging. STEAM employs the <a href="/facts/Time-stretch_analog-to-digital_converter/rlYgQ1Yj">Photonic Time Stretch</a> with internal <a href="/facts/Raman_amplification/c2cNDHyc">Raman amplification</a> to realize optical image amplification to circumvent the fundamental trade-off between sensitivity and speed that affects virtually all optical imaging and sensing systems. This method uses a single-pixel <a href="/facts/Photodetector/7cSkXS6s">photodetector</a>, eliminating the need for the detector array and readout time limitations. Avoiding this problem and featuring the optical image amplification for improvement in sensitivity at high image acquisition rates, STEAM's shutter speed is at least 1000 times faster than the best <a href="/facts/Charge-coupled_device/l6xffIcz">CCD</a> and <a href="/facts/Complementary_metal%25E2%2580%2593oxide%25E2%2580%2593semiconductor/NJIWYgBl">CMOS</a> cameras. Its frame rate is 1000 times faster than the fastest <a href="/facts/Charge-coupled_device/l6xffIcz">CCD cameras</a> and 10–100 times faster than the fastest <a href="/facts/Active-pixel_sensor/6Trt4SWj">CMOS cameras</a>.
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Serial time-encoded amplified microscopy open-in-new

Serial time-encoded amplified microscopy