Menu
Home
People
Places
Arts
History
Plants & Animals
Science
Life & Culture
Technology
Reference.org
Diglyceride acyltransferase
open-in-new
<p>Diglyceride acyltransferase (or <i>O</i>-acyltransferase), DGAT, catalyzes the formation of <a href="/facts/Triglycerides/BQmjv4A0">triglycerides</a> (triacylglycerols) from <a href="/facts/Diacylglycerol/hRnhfVIk">diacylglycerol</a> and <a href="/facts/Acyl-CoA/uWNxxzSj">acyl-CoA</a>. The reaction catalyzed by DGAT is considered the terminal and only <a href="/facts/Committed_step/v2Y7dwsL">committed step</a> in the acyl-CoA-dependent triglyceride synthesis, universally important in animal, plants, and microorganisms. The conversion is essential for intestinal absorption (i.e. DGAT1) and adipose tissue formation (i.e. DGAT2) in mammalian. DGAT1 are homologous to other <a href="/facts/MBOAT/PUgqw4ID">membrane-bound <i>O</i>-acyltransferases</a>, but not all other DGATs. </p>